Cobalamine
- CAS No.
- 68-19-9
- Chemical Name:
- Cobalamine
- Synonyms
- CYANOCOBALAMIN;Vb12;METHYLCOBALAMIN;CYANOCOBALAMINE;hemomin;cyanocobalamin (b12);COBALAMINE;hydroxycobalamin chloride;VIT B12;lldfactor
- CBNumber:
- CB00129347
- Molecular Formula:
- C63H88CoN14O14P
- Molecular Weight:
- 1355.37
- MDL Number:
- MFCD00151092
- MOL File:
- 68-19-9.mol
- MSDS File:
- SDS
Melting point | >300°C |
---|---|
alpha | 23656 -59 ± 9° (dil aq soln) |
Boiling point | >300 °C |
Flash point | 9℃ |
storage temp. | 2-8°C |
solubility | Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in acetone. The anhydrous substance is very hygroscopic. |
pka | pKa 3.28±0.04(H2O,D2O t=23±0.5 Iunspeci?ed) (Uncertain) |
form | Crystalline Powder or Crystals |
color | Red to dark red |
Odor | dark red cryst. or powd., odorless and tasteless |
Water Solubility | Soluble |
Sensitive | Hygroscopic |
Merck | 14,10014 |
BRN | 4122889 |
Exposure limits | NIOSH: IDLH 25 mg/m3 |
Stability | Hygroscopic. Keep cold and dry. |
InChIKey | RMRCNWBMXRMIRW-WZHZPDAFSA-L |
LogP | 3.570 (est) |
Substances Added to Food (formerly EAFUS) | VITAMIN B-12 |
SCOGS (Select Committee on GRAS Substances) | Vitamin B12 (cyanocobalamin) |
NCI Dictionary of Cancer Terms | cyanocobalamin |
FDA UNII | P6YC3EG204 |
NCI Drug Dictionary | Berubigen |
ATC code | B03BA01,B03BA51 |
EPA Substance Registry System | Vitamin B12 (68-19-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS06,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H225-H301+H311+H331-H370 | |||||||||
Precautionary statements | P210-P260-P280-P301+P310-P311 | |||||||||
Hazard Codes | ||||||||||
HS Code | 2936260000 | |||||||||
Toxicity | LD50 intravenous in mouse: 2gm/kg | |||||||||
NFPA 704 |
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Cobalamine price More Price(55)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | V-019 | Cyanocobalamin (Vitamin B12) solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 68-19-9 | 1mL | $85.2 | 2024-03-01 | Buy |
Sigma-Aldrich | C3607 | Cyanocobalamin meets USP testing specifications | 68-19-9 | 5g | $762 | 2024-03-01 | Buy |
Sigma-Aldrich | 47869 | Cyanocobalamin (B12) analytical standard | 68-19-9 | 100mg | $44.9 | 2024-03-01 | Buy |
Sigma-Aldrich | 43107 | Cyanocobalamin tested according to Ph. Eur. | 68-19-9 | 10G | $1460 | 2024-03-01 | Buy |
Sigma-Aldrich | 1152011 | Cyanocobalamin (crystallline) United States Pharmacopeia (USP) Reference Standard | 68-19-9 | 2X150MG | $447 | 2024-03-01 | Buy |
Cobalamine Chemical Properties,Uses,Production
Description
Cobalamine is a synthetic compound of vitamin B12 used to treat vitamin deficiencies. Chemically, cyanocobalamin is classified as a "corrinoid," representing a crystallizable cobalt complex. The name "cyanocobalamin" is derived from including a cyanide group within the molecule. Cyanocobalamin is approved by the United States Food and Drug Administration (FDA) for pernicious anemia, malabsorption, atrophic gastritis, gastrectomy, Helicobacter pylori infection, and other conditions.
Uses
Cyanocobalamin injection is used to treat and prevent a lack of vitamin B12 that may be caused by any of the following: pernicious anemia (lack of a natural substance needed to absorb vitamin B12 from the intestine); certain diseases, infections, or medications that decrease the amount of vitamin B12 absorbed from food; or a vegan diet (strict vegetarian diet that does not allow any animal products, including dairy products and eggs). Cyanocobalamin injection is in a class of medications called vitamins. Because it is injected straight into the bloodstream, it can be used to supply vitamin B12 to people who cannot absorb this vitamin through the intestine.
Side effects
Shortness of breath (even with mild exertion), swelling, rapid weight gain. Pulmonary edema, congestive heart failure, peripheral vascular thrombosis. Hypokalemia--leg cramps, irregular heartbeats, tingling/numbness, muscle weakness, or limp feeling.
Cobalamine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
APOLLO HEALTHCARE RESOURCES | +6596580999 | sales@apollo-healthcare.com.sg | Singapore | 400 | 58 |
Siyang Liaoning Biochemical Products Co. Ltd | +86-15221114306; +8615221114306 | 2594582574@qq.com | China | 574 | 58 |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9329 | 58 |
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 | yuxin@yuxchem.com | China | 158 | 58 |
Guangzhou Tosun Pharmaceutical Limited | +8618922120635 | sales@toref-standards.com | China | 1000 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6011 | 58 |
Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 | admin@china-yime.com | China | 563 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
Suzhou Sanyi Polymer Chemical Technology Co., Ltd. | +8615571922873 | 15571922873@163.com | China | 106 | 58 |
shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
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View Lastest Price from Cobalamine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-02-27 | pure vitamin b12 powder CAS NO.13408-78-1 Cobalamine kf-wang(at)kf-chem.com
13408-78-1
|
US $25.00 / Kg/Drum | 10g | 99.8% | 5000 | Hebei Aicrowe Biotech Co., Ltd |
- pure vitamin b12 powder CAS NO.13408-78-1 Cobalamine kf-wang(at)kf-chem.com
13408-78-1
- US $25.00 / Kg/Drum
- 99.8%
- Hebei Aicrowe Biotech Co., Ltd