| Identification | More | [Name]
1-Dodecanethiol | [CAS]
112-55-0 | [Synonyms]
1-DODECANETHIOL
1-MERCAPTODODECANE
DODECYL MERCAPTAN
LAURYL MERCAPTAN
MERCAPTAN C12
NDM
N-DODECANETHIOL
N-DODECYL MERCAPTAN
1-Dodecyl mercaptan
1-dodecylmercaptan
Dodecane-1-thiol
Dodecanethiol-(1)
dodecanethiol(non-specificname)
dodecanethiolnormal
Dodecylthiol
laurylmercaptide
m-dodecylmercaptan
m-laurylmercaptan
NCI-C60935
n-Dodecylthiol | [EINECS(EC#)]
203-984-1 | [Molecular Formula]
C12H26S | [MDL Number]
MFCD00004885 | [Molecular Weight]
202.4 | [MOL File]
112-55-0.mol |
| Chemical Properties | Back Directory | [Appearance]
clear liquid | [Melting point ]
-7 °C | [Boiling point ]
266-283 °C(lit.)
| [density ]
0.845 g/mL at 25 °C(lit.)
| [vapor density ]
7 (vs air)
| [vapor pressure ]
0.002 hPa (20 °C) | [FEMA ]
4581 | DODECANETHIOL | [refractive index ]
n20/D 1.459(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Liquid | [pka]
10.49±0.10(Predicted) | [color ]
Clear | [Odor]
Stench | [Odor Type]
sulfurous | [Water Solubility ]
IMMISCIBLE | [Sensitive ]
Air Sensitive | [λmax]
205nm(lit.) | [JECFA Number]
1924 | [BRN ]
969337 | [Exposure limits]
ACGIH: TWA 0.1 ppm
NIOSH: Ceiling 0.5 ppm(4.1 mg/m3) | [Stability:]
Air Sensitive | [InChIKey]
WNAHIZMDSQCWRP-UHFFFAOYSA-N | [LogP]
6.18 | [CAS DataBase Reference]
112-55-0(CAS DataBase Reference) | [NIST Chemistry Reference]
1-Dodecanethiol(112-55-0) | [EPA Substance Registry System]
112-55-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi,N,F | [Risk Statements ]
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R42/43:May cause sensitization by inhalation and skin contact .
R36/37/38:Irritating to eyes, respiratory system and skin .
R67:Vapors may cause drowsiness and dizziness.
R65:Harmful: May cause lung damage if swallowed.
R62:Possible risk of impaired fertility.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R48/20:Harmful: danger of serious damage to health by prolonged exposure through inhalation .
R38:Irritating to the skin.
R11:Highly Flammable. | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S37/39:Wear suitable gloves and eye/face protection .
S63:In case of accident by inhalation, remove casualty to fresh air and keep at rest.
S62:If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S36/37:Wear suitable protective clothing and gloves .
S33:Take precautionary measures against static discharges .
S29:Do not empty into drains .
S16:Keep away from sources of ignition-No smoking .
S9:Keep container in a well-ventilated place . | [RIDADR ]
UN 1208 3/PG 2 | [WGK Germany ]
3
| [RTECS ]
JR3155000
| [Autoignition Temperature]
230 °C | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29309070 | [Hazardous Substances Data]
112-55-0(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: > 2000 mg/kg |
| Hazard Information | Back Directory | [General Description]
Oily colorless liquid with a mild skunk odor. Freezing point 19°F. | [Reactivity Profile]
LAURYL MERCAPTAN(112-55-0) is incompatible with bases, oxidizing agents, reducing agents and alkali metals. Easily oxidized to disulfide. | [Air & Water Reactions]
Air and moisture sensitive. Insoluble in water. Reacts vigorously with water or steam. | [Health Hazard]
Liquid is irritating to skin, eyes, and mucous membranes. Ingestion may cause nausea. Repeated skin exposure can cause dermatitis and may produce a sensitizing effect. | [Fire Hazard]
Special Hazards of Combustion Products: Poisonous and irritating gases (e.g., sulfur dioxide) are generated in fires. | [Chemical Properties]
clear liquid | [Uses]
1-Dodecanethiol can be used for the synthesis of thiol-stabilized metal nanoparticles (NPs), such as gold nanoparticles and silver nanoparticles, which have been produced for use as catalysts, electronic devices, fillers, sensors and active components in composite materials, and other applications.
This molecule is used for the production of hydrophobic SAMs. It can also be used in mixed SAMs to give a hydrophobic background and act as a spacer to move other functional groups or domains farther apart. | [Uses]
1-Dodecanethiol is used in the preparation of hydrophobic or mixed self-assembled monolayers. It is also employed as a chain transfer agent for radical polymerization. Further, it is utilized as a polymerization inhibitor in polyurethane and neoprene adhesives, which finds application in the footwear industry. In addition to this, it acts as a protein regenerating agent used for the regeneration of native proteins from mercuribenzoate. | [Uses]
Dodecyl mercaptan is a poymerization inhibitor added to polyurethane resins and Neoprene glues for use, e.g., in the shoe industry. | [Preparation]
Preparation of 1-dodecanethiol: 1-Bromododecane, thiourea and 95% ethanol are heated to reflux reaction, then sodium hydroxide solution is added and heated. After the reaction is finished, cooled and left to stratify, the oil layer is the crude thiol. The crude product is washed with water, dried, distilled, and distilled under reduced pressure, which is 1-dodecanethiol. | [Purification Methods]
Dry it with CaO for several days, then distil it from CaO. [Beilstein 1 IV 1851.] |
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