Back to ChemicalBook Home--->CAS DataBase List--->1185-57-5

1185-57-5

1185-57-5 Structure

1185-57-5 Structure
IdentificationMore
[Name]

Ammonium ferric citrate
[CAS]

1185-57-5
[Synonyms]

AMMONIUM FERRIC CITRATE
AMMONIUM FERRIC CITRATE, BROWN
AMMONIUM FERRIC CITRATE, GREEN
AMMONIUM IRON(+3)CITRATE, BROWN
AMMONIUM IRON(+3)CITRATE, GREEN
AMMONIUM IRON(III) CITRATE
AMMONIUM IRON(III) CITRATE, BROWN
AMMONIUM IRON(III) CITRATE GREEN
AMMONIUM IRON(III) CITRATE RED-BROWN
CITRIC ACID AMMONIUM IRON(III) SALT
FERRIC AMMONIUM CITRATE
FERRIC AMMONIUM CITRATE, GREEN
IRON(+3)AMMONIUM CITRATE, BROWN
IRON(+3)AMMONIUM CITRATE, GREEN
IRON AMMONIUM CITRATE
IRON AMMONIUM CITRATE, BROWN
IRON AMMONIUM CITRATE, GREEN
IRON (III) AMMONIUM CITRATE
IRON (III) AMMONIUM CITRATE, BROWN
IRON (III) AMMONIUM CITRATE, GREEN
[EINECS(EC#)]

214-686-6
[Molecular Formula]

C12H22FeN3O14
[MDL Number]

MFCD00013099
[Molecular Weight]

488.16
[MOL File]

1185-57-5.mol
Chemical PropertiesBack Directory
[Appearance]

brownish-yellow to brown powder
[storage temp. ]

Store at RT.
[form ]

powder
[Water Solubility ]

1200 g/L (20 ºC)
[Sensitive ]

Hygroscopic
[Merck ]

14,4017
[CAS DataBase Reference]

1185-57-5(CAS DataBase Reference)
[EPA Substance Registry System]

1185-57-5(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[RIDADR ]

UN 9118
[WGK Germany ]

3
[RTECS ]

GE7540000
[F ]

3-8
[HS Code ]

29181500
[Hazardous Substances Data]

1185-57-5(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium chlorate-->Ferrous sulfate heptahydrate-->Red prussiate-->Paste-->LIMONIN(SH)
[Preparation Products]

Nicotinic acid
Hazard InformationBack Directory
[General Description]

FERRIC AMMONIUM CITRATE(1185-57-5) is a yellowish brown to red solid with a faint odor of ammonia. FERRIC AMMONIUM CITRATE(1185-57-5) is soluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. FERRIC AMMONIUM CITRATE(1185-57-5) is used in medicine, in making blueprints, and as a feed additive.
[Reactivity Profile]

Acidic salts, such as FERRIC AMMONIUM CITRATE, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions. Special Hazards of Combustion Products: Toxic oxides of nitrogen or ammonia gas may be formed in fires [USCG, 1999].
[Air & Water Reactions]

Water soluble.
[Health Hazard]

Inhalation of dust irritates nose and throat. Ingestion causes irritation of mouth and stomach. Dust irritates eyes and causes mild irritation of skin on prolonged contact.
[Fire Hazard]

Special Hazards of Combustion Products: Toxic oxides of nitrogen or ammonia gas may be formed in fires.
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Ferric ammonium citrate(1185-57-5).msds
Questions And AnswerBack Directory
[Maximal allowable residue and maximal allowable usage amount]

Name of additive: Ammonium ferric citrate [Mineral]

Function of additive: Nutrition Enhancer

 Maximal allowable residue(g/kg): /

Food allowed to use it as additive Maximal allowable amount(g/kg)
Salt, sandwich sugar 4000 ~ 8000mg (1: strengthened amount calculated on the element iron: cereal and its products 24 ~ 48mg / kg; beverage:10 ~ 20mg / kg dairy products; infant food 60 ~ 100mg / kg; sandwich sugar 600 ~ 1200 mg; 2. the iron content in various kinds of salts: ferrous sulfate (contains seven crystal water molecules),  ferrous lactate (Including three crystal water molecules) 19.39%; iron citrate (containing 5 crystal water molecules ) 16.67%; ferrous fumarate:32.9%; ferrous gluconic acid:12%; ferric ammonium citrate 16% 3. Iron source can also be applied of the heme iron extracted from the pig blood with calculation on the iron elements upon strengthening 4. Other iron salts such as ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous succinate, reduced iron, electrolytic iron can also apply it; calculated on the element iron upon strengthening.
High-iron cereals and their products (daily limit of such food: 50g)   1200 ~ 1350mg (1 the strengthening amount is calculated on the element iron: cereals and their products: 24 ~ 48mg / kg; drinks 10 ~ 20mg / kg; dairy products, infant food: 60 ~ 100mg / kg; sandwich sugar: 600 ~ 1200mg 2. The iron content in various kinds of iron salts ferrous sulfate (contains seven crystal water molecules),  ferrous lactate (Including three crystal water molecules) 19.39%; iron citrate (containing 5 crystal water molecules ) 16.67%; ferrous fumarate:32.9%; ferrous gluconic acid:12%; ferric ammonium citrate 16% 3. Iron source can also be applied of the heme iron extracted from the pig blood with calculation on the iron elements upon strengthening 4. Other iron salts such as ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous succinate, reduced iron, electrolytic iron can also apply it; calculated on the element iron upon strengthening.
    Dairy products, infant food 400~800mg (1 the strengthening amount is calculated on the element iron: cereals and their products: 24 ~ 48mg / kg; drinks 10 ~ 20mg / kg; dairy products, infant food: 60 ~ 100mg / kg; sandwich sugar: 600 ~ 1200mg 2. The iron content in various kinds of iron salts ferrous sulfate (contains seven crystal water molecules),  ferrous lactate (Including three crystal water molecules) 19.39%; iron citrate (containing 5 crystal water molecules ) 16.67%; ferrous fumarate:32.9%; ferrous gluconic acid:12%; ferric ammonium citrate 16% 3. Iron source can also be applied of the heme iron extracted from the pig blood with calculation on the iron elements upon strengthening 4. Other iron salts such as ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous succinate, reduced iron, electrolytic iron can also apply it; calculated on the element iron upon strengthening.
Drink 70 ~ 140mg (1 the strengthening amount is calculated on the element iron: cereals and their products: 24 ~ 48mg / kg; drinks 10 ~ 20mg / kg; dairy products, infant food: 60 ~ 100mg / kg; sandwich sugar: 600 ~ 1200mg 2. The iron content in various kinds of iron salts ferrous sulfate (contains seven crystal water molecules),  ferrous lactate (Including three crystal water molecules) 19.39%; iron citrate (containing 5 crystal water molecules ) 16.67%; ferrous fumarate:32.9%; ferrous gluconic acid:12%; ferric ammonium citrate 16% 3. Iron source can also be applied of the heme iron extracted from the pig blood with calculation on the iron elements upon strengthening 4. Other iron salts such as ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous succinate, reduced iron, electrolytic iron can also apply it; calculated on the element iron upon strengthening.
  Cereals and their products 160 ~ 330mg (1 the strengthening amount is calculated on the element iron: cereals and their products: 24 ~ 48mg / kg; drinks 10 ~ 20mg / kg; dairy products, infant food: 60 ~ 100mg / kg; sandwich sugar: 600 ~ 1200mg 2. The iron content in various kinds of iron salts ferrous sulfate (contains seven crystal water molecules),  ferrous lactate (Including three crystal water molecules) 19.39%; iron citrate (containing 5 crystal water molecules ) 16.67%; ferrous fumarate:32.9%; ferrous gluconic acid:12%; ferric ammonium citrate 16% 3. Iron source can also be applied of the heme iron extracted from the pig blood with calculation on the iron elements upon strengthening 4. Other iron salts such as ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous succinate, reduced iron, electrolytic iron can also apply it; calculated on the element iron upon strengthening.
[Uses]

1.  Nutritional supplements. Iron enhancer, anti-anemia iron agent (each oral 1 ~ 2g). It can be added to biscuits, milk powder, being not suitable for being applied to food that is not colored.
2.  Ammonium ferric citrate, as a food iron fortifier, has its absorption effect be better than inorganic iron. China provides that it can be used for salt and sandwich sugar with the usage amount of 4000 ~ 8000mg / kg; in high-iron cereal and its products (daily limit: 50 g of such food): 1200 ~ 1350mg / kg; dairy and infant food: 400 to 800 mg / kg; in cereals and their products, 160 to 330 mg / kg; beverages: 70 to 140 mg / kg.
3.  It can be used for the pharmaceutical industry
4.  It is used in the photographic industry and the pharmaceutical industry
5.  It can be used as the nutritional supplements (iron fortifier). For dairy products, bread and wheat flour. Also used as anti-caking agent.
6.  It can be used in bacterial culture medium for measuring aluminum, photography, blue print, blood and so on.
7.  The brown product can be used as a hematinic drug for the treatment of iron deficiency anemia; it can be used as food additives; according to the provision of Japanese, "Food Additives", iron content: 16.5% -21.2%. The brown product and green product are both chemical-sensitive substances with the green goods being more sensitive to light than brown goods. Paper coated with green ferric ammonium citrate and red blood salt (potassium ferricyanide) is called blue blueprint paper. Upon the exposure, the trivalent iron in the citric acid salt is converted to bivalent, coming across water to give turnbull's blue, so the lightened part exhibits blue color while the rest part is still white, yielding a blue matrix white line pattern.
[Production method]

The ferric hydroxide is dissolved in citric acid, neutralized with ammonia solution, followed by drying to obtain it. (1) Preparation of ferric hydroxide Ferrous sulfate was added to the water, and sulfuric acid was slowly added thereto under stirring, followed by addition of an aqueous sodium chlorate solution. Then stir vigorously and raise the temperature to above 80 ℃; further add sodium chlorate. Stir until the reaction is terminated (no further ferrous reaction through ferricyanide test) to obtain the ferric sulfate solution. Add this solution to the reaction tank, add sodium hydroxide solution and stir vigorously with the reaction temperature of 80-90 °; when the reaction solution turns from viscous to thin, add water for washing until the sulfate and chlorine meet the requirements. Dry to get the iron hydroxide. (2) Preparation of ferric ammonium citrate; add citrate, ferric hydroxide and water into the reaction tank, stir and control the temperature at 95 ℃ above and maintain the temperature for 1h. And then cooled to 50?C and sent into ammonia under stirring. Stand for more than 48h. The supernatant was filtered and the filtrate was concentrated to a paste and dried at 80 ° C to obtain ferric ammonium citrate. The total yield of ferrous sulfate is 73-75%.
The same procedure as in preparation method 2 of brown ferric ammonium citrate.
Adding ammonium hydroxide to the ferric sulfate to generate ferrous hydroxide precipitate; filter and wash with water to no sulfate reaction anymore; then add  citrate and heat to 60?C to completely dissolve the precipitate; neutralize with ammonia hydroxide and concentrate to a syrupy state, and coat on a glass plate, and dry to obtain a small sheet product.
Fe2 (SO4) 3 + 6NH3 + 6H2O → 3 (NH4) 2SO4 + 2Fe (OH) 3 ↓
2C6H8O7 + 3NH4OH + Fe (OH) 3 → (C6H5O7) 2Fe (NH4) 3 + 6H2O
It can also taken of ferrous sulfate as raw materials. 28g FeSO4 • 7H2O was dissolved in 4 mL water; add 3 mL 98% concentrated sulfuric acid and then drop 5mL 36% hydrogen peroxide; heat to 83 ℃ and stir for 0.5h; the blue color upon potassium ferricyanide test can tell the termination of the reaction; further add 100 mL distilled water, and 40% NaOH was added at 80 ° C with stirring to make the solution be alkaline. The precipitate was suction filtered and washed with hot water until no sulfate was present any more. The prepared Fe (OH) 3 was added to a citric acid solution (14 g/100 mL water) and stirred at 95 ° C for 1 h. The solution was then cooled to 50 ° C and an appropriate amount of aqueous ammonia was added. The solution was cooled to room temperature. Evaporate the supernatant to a paste with drying at 60 ~ 80 ° C to obtain the product with a yield of 91%.
A considerable amount of citric acid solution was added to ferric hydroxide produced from reaction between the ferric sulfate and aqueous ammonia; the concentrated slurry was coated on a glass plate, dried, and then peeled off from the glass plate.
Ferric hydroxide is dissolved in citric acid, with neutralization with ammonia hydroxide and evaporation at 60 ° C to obtain.
[Hazards & Safety Information]

Category:  Toxic substances
Toxic classification:   poisoning
Acute toxicity :  Oral - rat LD:> 2000 mg / kg
Flammable and hazardous characteristics:   being combustible with fire discharging iron and nitrogen oxide-containing spicy smoke
Storage and transport characteristics:   Treasury: low temperature, ventilated, dry
Fire extinguishing agent :  water, carbon dioxide, dry powder, sand
Occupational Standard:   TWA 1 mg / m3
Spectrum DetailBack Directory
[Spectrum Detail]

Ammonium ferric citrate(1185-57-5)IR1
Ammonium ferric citrate(1185-57-5)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Ammonium iron(III) citrate, 16.5 to 18.5% Fe(1185-57-5)
[Alfa Aesar]

Ammonium iron(III) citrate, brown(1185-57-5)
[Sigma Aldrich]

1185-57-5(sigmaaldrich)
Company Name:J & K SCIENTIFIC LTD.  
Telephone:400-666-7788 +86-10-82848833
Contact Fax:+86-10-82849933
Website:www.jkchemical.com
Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.  
Telephone:+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)
Contact Fax:+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)
Website:www.meryer.com
Company Name:Alfa Aesar  
Telephone:400-610-6006; 021-67582000
Contact Fax:021-67582001/03/05
Website:www.alfachina.cn
Company Name:Energy Chemical  
Telephone:021-58432009 / 400-005-6266
Contact Fax:021-58436166-800
Website:www.energy-chemical.com
Company Name:JinYan Chemicals(ShangHai) Co.,Ltd.  
Telephone:13817811078,021-50426030
Contact Fax:86-021-50426522,50426273
Website:www.jingyan-chemical.com
Company Name:Adamas Reagent, Ltd.   
Telephone:400-600-9262
Contact Fax:021-51701678
Website:www.tansoole.com
Company Name:Shanghai Hanhong Chemical Co., Ltd.  
Telephone:021-61521197,021-54302127,021-54306202,021-61525701,021-54308259
Contact Fax:+86-21-54291107
Website:www.hanhonggroup.com
Company Name:Chengdu XiYa Chemical Technology Co., Ltd.  
Telephone:4008-626-111
Contact Fax:028-84752058
Website:www.xiyashiji.com
Company Name:BEST-REAGENT  
Telephone:028-85973071 028-85973075
Contact Fax:028-85973075
Website:www.best-reagent.com
Company Name:Tianjin heowns Biochemical Technology Co., Ltd.  
Telephone:400 638 7771
Contact Fax:
Website:www.heowns.com
Company Name:Sinopharm Chemical Reagent Co,Ltd.  
Telephone:86-21-63210123
Contact Fax:86-21-63290778 86-21-63218885
Website:www.reagent.com.cn
Company Name:Spectrum Chemical Manufacturing Corp.  
Telephone:021-67601398-808
Contact Fax:021-57711696
Website:www.spectrumchina.com.cn
Company Name:Chengdu Ai Keda Chemical Technology Co., Ltd.  
Telephone:4008-755-333 ; 028-86676798 ; 028-86757656
Contact Fax:028-86757656
Website:www.aikeshiji.com
Company Name:Thermo Fisher Scientific  
Telephone:800-810-5118
Contact Fax:+86-10-84193589
Website:www.thermo.com.cn
Company Name:Beijing innoChem Science & Technology Co.,Ltd.  
Telephone:400-810-7969 010-59572699
Contact Fax:010-59572688
Website:www.inno-chem.com.cn
Company Name:Cheng Du Micxy Chemical Co.,Ltd  
Telephone:028-85632863 028-64559668 18048500443
Contact Fax:028-85632863 QQ: 2509670926
Website:www.micxy.com
Company Name:9ding chemical ( Shanghai) Limited  
Telephone:4009209199
Contact Fax:86-021-52271987
Website:www.9dingchem.com
Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD  
Telephone:021-20337333/400-620-6333
Contact Fax:021-50323701
Website:www.aladdin-e.com
Tags:1185-57-5 Related Product Information
2338-05-8 7705-08-0 1336-21-6 3522-50-7 77-92-9 7782-91-4 6484-52-2 7783-20-2 12125-02-9 3458-72-8 10138-04-2 1185-57-5 631-61-8