| Identification | More | [Name]
alpha-Chloralose | [CAS]
15879-93-3 | [Synonyms]
1,2-O-[2,2,2-TRICHLOROETHYLIDENE]-ALPHA-D-GLUCOFURANOSE
1,2-O-(2,2,2-TRICHLOROETHYLIDENE)-D-GLUCOFURANOSE
A-CHLORALOSE
A-D-GLUCOCHLORALOSE
A-D-GLUCOCHLOROLOSE
ALFA-4(R)
ALFAMAT(R)
ALFA Z(R)
ALPHA-CHLORALOSE
ALPHA-D-CHLORALOSE
ALPHA-D-(+)-GLUCOCHLORALOSE
ALPHA-D-GLUCOCHLORALOSE
ANHYDRO-D-GLUCOCHLORAL
ANHYDROGLUCOCHLORAL
CHLORALOSE
CHLORALOSE, A-
GLUCOCHLORAL
GLUCOCHLORALOSE
(R)-1,2-O-(2,2,2-TRICHLOROETHYLIDENE)-A-D-GLUCOFURANOSE
(r)-1,2-o-(2,2,2-trichloroethylidene)-alpha-d-glucofuranose | [EINECS(EC#)]
240-016-7 | [Molecular Formula]
C8H11Cl3O6 | [MDL Number]
MFCD00005542 | [Molecular Weight]
309.53 | [MOL File]
15879-93-3.mol |
| Chemical Properties | Back Directory | [Appearance]
needle-like crystals or powder | [Melting point ]
178-182 °C
| [alpha ]
18 º (c=2, 95% C2H5OH) | [Boiling point ]
424.33°C (rough estimate) | [density ]
1.6066 (rough estimate) | [vapor pressure ]
Negligible at room temperature | [refractive index ]
1.5320 (estimate) | [solubility ]
ethanol: 10 mg/mL or yellow-brown, clear to slightly hazy, colorless to faintly yellow
| [form ]
neat | [pka]
12.89±0.60(Predicted) | [color ]
White to Almost white | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [optical activity]
[α]20/D +17±2°, 5 hr, c = 2% in ethanol | [Water Solubility ]
0.44 g/100 mL (15 ºC) | [Merck ]
14,2072 | [BRN ]
85418 | [LogP]
1.020 | [Uses]
Coating seeds to protect them from birds. | [CAS DataBase Reference]
15879-93-3(CAS DataBase Reference) | [EPA Substance Registry System]
15879-93-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/22:Harmful by inhalation and if swallowed . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S24/25:Avoid contact with skin and eyes .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . | [RIDADR ]
3249 | [WGK Germany ]
1
| [RTECS ]
FM9450000
| [TSCA ]
Yes | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29400090 | [Safety Profile]
Poison by ingestion,
subcutaneous, and intraperitoneal routes.
Questionable carcinogen with experimental
tumorigenic data. When heated to
decomposition it emits toxic fumes of Cl-. | [Toxicity]
LD50 orally in mice: 400 mg/kg (Schafer) |
| Hazard Information | Back Directory | [Hazard]
May cause addiction, highly toxic. | [Description]
Chloralose, (R)-1,2-O-(2,2,2-trichloroethylidene)-
α-D-glucofuranose, is a crystalline powder which is soluble in water,
fairly soluble in alcohol, diethyl ether, glacial acetic acid,
sparingly soluble in chloroform, practically insoluble in
petroleum ether.
Chloralose is produced by reaction of glucose with waterfree
chloral under heating (21). | [Chemical Properties]
needle-like crystals or powder | [Metabolic pathway]
Chloralose is effectively a chloral generator which, in turn, affords trichloroethanol
by metabolism. This is the narcotic agent. Sleep is induced in
mice before death and therefore the compound is regarded as a humane
mouse killer. It is particularly effective when a quick clearout is required
but there is evidence that mice can become tolerant. | [Degradation]
Chloralose is hydrolysed by acid and base to glucose and chloral (2, trichloroacetaldehyde). |
|
|