| Identification | Back Directory | [Name]
1-METHOXY-4-NITRONAPHTHALENE | [CAS]
4900-63-4 | [Synonyms]
methyl4-nitronaphthylether
1-Methoxy-4-nitronaphthalin
1-Nitro-4-methoxynaphthalene
4-Methoxy-1-nitronaphthalene
1-METHOXY-4-NITRONAPHTHALENE
Naphthalene,1-methoxy-4-nitro-
1-Methoxy-4-nitronaphthalene,99%
1-Methoxy-4-nitronaphthalene 99% | [EINECS(EC#)]
225-528-0 | [Molecular Formula]
C11H9NO3 | [MDL Number]
MFCD00003926 | [MOL File]
4900-63-4.mol | [Molecular Weight]
203.19 |
| Chemical Properties | Back Directory | [Appearance]
yellow to orange crystalline powder | [Melting point ]
83-85 °C(lit.)
| [Boiling point ]
341.49°C (rough estimate) | [density ]
1.2621 (rough estimate) | [refractive index ]
1.4950 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature |
| Hazard Information | Back Directory | [Chemical Properties]
yellow to orange crystalline powder | [Uses]
1-Methoxy-4-nitronaphthalene is used as a reagent in the synthesis of UMI-77 (U700850); a small molecule inhibitor of Mcl-1 which blocks and attenuates pancreatic cell cancer growth. Also an anticancer agent. | [Synthesis Reference(s)]
Synthesis, p. 70, 1985 DOI: 10.1055/s-1985-31110 | [Purification Methods]
Purify it by chromatography on silica gel, then recrystallise it from MeOH or EtOH (yellow needles). [Hodgson & Habeshaw J Chem Soc 47 1942, Bunce et al. J Org Chem 52 4214 1987, Beilstein 6 H 616, 6 III 2938.] |
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| Company Name: |
Qingfeng Chem Gold
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| Tel: |
18672943286 |
| Website: |
https://www.whqfchem.com |
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