| Identification | More | [Name]
2-Bromoethanol | [CAS]
540-51-2 | [Synonyms]
2-bromo-1-ethanol
2-BROMOETHANOL
2-Bromoethyl alcohol
beta-Bromoethyl alcohol
BROMOETHANOL-2
ETHYLENE BROMOHYDRIN
1-Bromo-2-ethanol
2-bromo-ethano
2-Hydroxyethyl bromide
2-hydroxyethylbromide
bromoethanol
-Bromoethylalcohol
CH2BrCH2OH(trans)
Glycol bromohydrin
glycolbromohydrin
Glycolbromo-hydrine
2-Bromo Ethenol
2-Bromorthanol
2-BROMOETHANOL, 1X1ML, TOL, 2000UG/ML
2-BROMOETHANOL, 1000MG, NEAT | [EINECS(EC#)]
208-748-1 | [Molecular Formula]
C2H5BrO | [MDL Number]
MFCD00002827 | [Molecular Weight]
124.96 | [MOL File]
540-51-2.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Melting point ]
-80 °C
| [Boiling point ]
56-57 °C/20 mmHg (lit.) | [density ]
1.763 g/mL at 25 °C(lit.)
| [vapor density ]
4.3 (vs air)
| [vapor pressure ]
2.4 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.492(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
1-5 g/100 mL at 19°C | [form ]
Liquid | [pka]
13.82±0.10(Predicted) | [color ]
Clear colorless to yellow | [Specific Gravity]
1.7629 (20/4℃) | [Stability:]
Stable, but probably light sensitive. Hygroscopic. Incompatible with strong oxidizing agents. Flammable. Forms an azeotrope with water. | [Water Solubility ]
1-5 g/100 mL at 19 ºC | [Sensitive ]
Light Sensitive | [Merck ]
14,3792 | [BRN ]
878140 | [InChIKey]
LDLCZOVUSADOIV-UHFFFAOYSA-N | [CAS DataBase Reference]
540-51-2(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethanol, 2-bromo-(540-51-2) | [EPA Substance Registry System]
540-51-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,T+ | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R34:Causes burns.
R40:Limited evidence of a carcinogenic effect.
R36/37/38:Irritating to eyes, respiratory system and skin .
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed .
R10:Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 2922 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
KJ8225000
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29055900 | [Safety Profile]
Poison by
intraperitoneal route. Questionable
carcinogen with experimental neoplastigenic
and tumorigenic data. Mutation data
reported. When heated to decomposition it
emits toxic fumes of Br-. See also |
| Questions And Answer | Back Directory | [Toxicity]
2-Bromoethanol can damage human body. The invasive ways of 2-bromoethanol include inhalation, ingestion and percutaneous absorption. 2-Bromoethanol has strong irritation to mucosa, upper respiratory tract, eyes and skin. Inhalation of 2-bromoethanol can cause death due to spasm, inflammation and edema of larynx and bronchus, chemical pneumonia and pulmonary edema. The manifestations of 2-bromoethanol poisoning include burning sensation, cough, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. |
| Hazard Information | Back Directory | [General Description]
Colorless to dark brown liquid. Sweet burning taste. | [Reactivity Profile]
2-BROMOETHANOL(540-51-2) forms an azeotrope with water; hydrolysis of aqueous solutions is accelerated by heat, alkalis and acids. | [Air & Water Reactions]
Hygroscopic. Water soluble. | [Hazard]
Irritant to eyes and mucous membranes. | [Fire Hazard]
This compound is combustible. | [Chemical Properties]
colourless liquid | [Uses]
2-Bromoethanol is used in selective reduction of nitroarenes (PcFe(II)/NaBH4/2-bromoethanol catalyst system). | [Uses]
Ethylene bromohydrin is not used much forany commercial purpose. The risk of expo sure to this compound arises when ethyleneoxide reacts with hydrobromic acid. | [Health Hazard]
The vapors of ethylene bromohydrin are anirritant to the eyes and mucous membranes.It is corrosive to the skin. Ingestion of thiscompound can produce moderate to severetoxic effects. The target organs are the CNS,gastrointestinal tract, and liver. The lethaldose in mice by the intraperitoneal route was80 mg/kg.
Ethylene bromohydrin manifested car cinogenicity in test animals. It caused tumorsin lungs and the gastrointestinal tract in micefrom intraperitoneal (150 mg/kg/8 weeks)and oral (43 mg/kg/80 weeks) dosages,respectively. It is a mutagen, positive to thehistidine reversion–Ames test. | [Waste Disposal]
Ethylene bromohydrin is mixed with a combustible solvent and burned in a chemicalincinerator. |
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