ChemicalBook--->CAS DataBase List--->588-36-3

588-36-3

588-36-3 Structure

588-36-3 Structure
IdentificationBack Directory
[Name]

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL
[CAS]

588-36-3
[Synonyms]

Methioprim
(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)ME...
4-AMINO-2-(METHYLTHIO)-5-PYRIMIDINEMETHANOL
(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL
4-AMINO-2-METHYLMERCAPTO-PYRIMIDINE-4-CARBINOL
4-AMINO-5-HYDROXYMETHYL-2-(METHYLTHIO)PYRIMIDINE
(4-AMINO-2-METHYLSULFANYL-PYRIMIDIN-5-YL)-METHANOL
(4-azanyl-2-methylsulfanyl-pyrimidin-5-yl)methanol
[Molecular Formula]

C6H9N3OS
[MDL Number]

MFCD08236793
[MOL File]

588-36-3.mol
[Molecular Weight]

171.22
Chemical PropertiesBack Directory
[Melting point ]

126-127°
[Boiling point ]

408.6±30.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[pka]

13.08±0.10(Predicted)
Hazard InformationBack Directory
[Chemical Properties]

White cryst powder
[Uses]

An intermediate used in the synthesis of Thiamine (T344185). Also, used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.
[Uses]

Tumor antagonist in mice.
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H332-H335
[Precautionary statements ]

P280-P305+P351+P338-P310
[HS Code ]

29335990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Tetrahydrofuran-->Sodium-->Toluene-->Acetic anhydride-->Lithium Aluminum Hydride-->Isopropyl alcohol-->Triethyl orthoformate-->Ethyl cyanoacetate-->Thiourea-->N,N-Dimethylformamide dimethyl acetal
Spectrum DetailBack Directory
[Spectrum Detail]

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL(588-36-3)1HNMR
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