| Identification | More | [Name]
Palmitic acid ethyl ester | [CAS]
628-97-7 | [Synonyms]
Ethyl cetylate
ETHYL HEXADECANOATE
ETHYL N-HEXADECANOATE
ETHYL PALMITATE
FEMA 2451
HEXADECANOIC ACID ETHYL ESTER
PALMITIC ACID ETHYL ESTER
Ethyl palmitate, (Ethyl hexadecanoate
Palmitic aci
FATTY ALCOHOLS ETHOXYLATED
ETHYL PALMITATE 95+%
Ethylpalmitate,97%
Ethyl palmita
ETHYL PALMITATE, NATURAL
Hexadecanoic acid ethyl
Palmitic acid ethyl | [EINECS(EC#)]
211-064-6 | [Molecular Formula]
C18H36O2 | [MDL Number]
MFCD00008996 | [Molecular Weight]
284.48 | [MOL File]
628-97-7.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless oily liquid after melting | [Melting point ]
24-26 °C (lit.) | [Boiling point ]
192-193 °C/10 mmHg (lit.) | [density ]
0.857 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.01Pa at 25℃ | [FEMA ]
2451 | [refractive index ]
n20/D 1.440(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
−20°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
neat | [color ]
Colourless to Off-White | [Specific Gravity]
0.857 | [Odor]
at 100.00 %. mild waxy fruity creamy milky balsamic greasy oily | [Odor Type]
waxy | [Water Solubility ]
IMMISCIBLE | [JECFA Number]
39 | [BRN ]
1782663 | [Dielectric constant]
2.7（103℃） | [LogP]
7.74 | [CAS DataBase Reference]
628-97-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Hexadecanoic acid, ethyl ester(628-97-7) | [EPA Substance Registry System]
628-97-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29157020 |
| Questions and Answers (Q&A) | Back Directory | [Description]
Palmitic acid ethyl ester, also known as ethyl palmitate, it the ethyl ester form of palmitic acid. It can be used as a hair- and skin-conditioning agent. It has been shown that the combination between palmitic acid ethyl ester and cobra venom factor can enhance the survival of heterologous erythrocyte. Recent study has also demonstrated the potential anti-inflammatory activity of palmitic acid ethyl ester in several animal models.
| [References]
Beste, Russell D, and R. D. Hamlin. "Skin permeation enhancer compositions comprising a monoglyceride and ethyl palmitate." US, US6267984. 2001.
Castro, O, et al. "Mechanism of ethyl palmitate and cobra venom factor enhancement of heterologous erythrocyte survival. " Proceedings of the Society for Experimental Biology & Medicine Society for Experimental Biology & Medicine 147.1(1974):106.
Saeed, N. M., et al. "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. " Toxicology & Applied Pharmacology 264.1(2012):84-93.
|
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless oily liquid after melting | [Chemical Properties]
Ethyl palmitate has a mild, waxy sweet odor. It is nearly tasteless and has a creamy mouthfeel. | [Occurrence]
Reported found in mutton, rye bread, rice, bourbon, vanilla, red sage, lemon balm, bilberry, Parmesan cheese,
maple syrup, Jamaican rum, whiskey, grape wine, cognac, cocoa, green tea, mango, corn oil and mastic gum leaf oil. | [Uses]
A fatty acid found in Amaranth oil; it shows inhibitory activity. | [Definition]
ChEBI: A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of palmitic acid with the hydroxy group of ethanol. | [Aroma threshold values]
Detection: 2 ppm | [Taste threshold values]
Taste characteristics at 30 ppm: waxy, fruity, creamy and fermented with a vanilla, balsamic nuance. | [Synthesis Reference(s)]
Tetrahedron, 48, p. 8775, 1992 DOI: 10.1016/S0040-4020(01)89450-3 | [General Description]
Ethyl palmitate is a one of the major volatile compounds found in cooked rice and Luzhou-flavor raw liquor. It occurs naturally in licorice root and chamomile. | [Synthesis]
Synthesized by immobilized lipase-catalyzed alcoholysis and esterification in organic solvents. |
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