ChemicalBook--->CAS DataBase List--->73334-07-3

73334-07-3

73334-07-3 Structure

73334-07-3 Structure
IdentificationMore
[Name]

Iopromide
[CAS]

73334-07-3
[Synonyms]

IOPROMIDE
N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N'-methylbenzene-1,3-dicarboxamide
1,3-benzenedicarboxamide,n,n’-bis(2,3-dihydroxypropyl)-5-((methoxyacetyl)amino
6-triiodo-)-n-methyl-4
shl414c
1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-
Ultravist
Ultravist 300
Ultravist 370
ZK 35760
N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N'-methylbenzene-1,3-dicarboxamide
N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetylamino)-N-methylisophthalamide
N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-1,3-benzenedicarboxamide
Proscope
[EINECS(EC#)]

277-385-9
[Molecular Formula]

C18H24I3N3O8
[MDL Number]

MFCD00867924
[Molecular Weight]

791.11
[MOL File]

73334-07-3.mol
Chemical PropertiesBack Directory
[Melting point ]

broad (160?C transition)
[Boiling point ]

840.9±65.0 °C(Predicted)
[density ]

2.173±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

Freely soluble in water and in dimethyl sulfoxide, practically insoluble in ethanol (96 per cent) and in acetone.
[form ]

neat
[pka]

10.62±0.70(Predicted)
[Stability:]

Hygroscopic
[CAS DataBase Reference]

73334-07-3(CAS DataBase Reference)
[EPA Substance Registry System]

1,3-Benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N1-methyl- (73334-07-3)
Safety DataBack Directory
[Hazard Codes ]

N
[Risk Statements ]

50/53
[Safety Statements ]

60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
[RTECS ]

CZ2230000
[HS Code ]

2924296000
[Toxicity]

LD50 in mice, rats (g iodine/kg body weight): 16.5, 11.4 i.v. (Muetzel)
Hazard InformationBack Directory
[Description]

Iopromide is a non-ionic, water-soluble X-ray contrast agent for intravascular administration. Iopromide can cause acute kidney injury and is used in animal models of contrast-induced nephropathy.
[Chemical Properties]

White Solid
[Uses]

Contrast molecule
[Uses]

Labelled Iopromide. Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).
[Definition]

ChEBI: A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A ater soluble x-ray contrast agent for intravascular administration.
[Brand name]

Ultravist (Berlex).
[General Description]

Iopromide is a low-osmolar,nonionic monomer with 48% bound iodine content. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.
[Side effects]

Most common adverse reactions (>1%) are headache, nausea, injection site and infusion site reactions, vasodilatation, vomiting, back pain, urinary urgency, chest pain, pain, dysgeusia, and abnormal vision.
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