| Identification | More | [Name]
BROMODICHLOROMETHANE | [CAS]
75-27-4 | [Synonyms]
BROMODICHLOROMETHANE
DICHLOROBROMOMETHANE
Bdcm
Bromdichlormethan
bromodichloro-methan
Bromodichoromethane
CHBrCl2
Dichloromonobromomethane
methane,bromodichloro-
Monobromodichloromethane
NCI-C55243
FC-20B1
BROMODICHLOROMETHANE, 1X1ML, MEOH, 5000U G/ML
BROMODICHLOROMETHANE, 1000MG, NEAT
BROMODICHLOROMETHANE, 98+%
BROMODICHLOROMETHANE, 1X1ML, MEOH, 200UG /ML
BROMODICHLOROMETHANE, STAB.
BROMODICHLOROMETHANE OEKANAL, AMYLENE STABILIZED, 1G
3ROMODICHLOROMETHANE, 98%, STAB. WITH POTASSIUM CARBONATE
Bromodicloromethane | [EINECS(EC#)]
200-856-7 | [Molecular Formula]
CHBrCl2 | [MDL Number]
MFCD00000824 | [Molecular Weight]
163.83 | [MOL File]
75-27-4.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to yellowish liquid | [Melting point ]
−55 °C(lit.) | [Boiling point ]
87 °C(lit.) | [density ]
1.98 g/mL at 25 °C(lit.)
| [vapor pressure ]
50 at 20 °C (Dreisbach, 1952) | [refractive index ]
n20/D 1.497(lit.)
| [Fp ]
87-89°C | [storage temp. ]
0-6°C
| [solubility ]
water: insoluble | [form ]
neat | [color ]
Clear, colorless liquid | [Water Solubility ]
3.032g/L(30 ºC) | [Merck ]
14,1417 | [BRN ]
1697005 | [Henry's Law Constant]
In seawater (salinity 30.4‰): 5.52, 10.51, and 18.97 at 0, 10, and 20 °C, respectively (Moore et
al., 1995) | [Stability:]
Light Sensitive, Volatile | [CAS DataBase Reference]
75-27-4(CAS DataBase Reference) | [IARC]
2B (Vol. 52, 71) 1999 | [EPA Substance Registry System]
Dichlorobromomethane (75-27-4) |
| Hazard Information | Back Directory | [Chemical Properties]
Bromodichloromethane (BDCM) is a colorless, heavy, non-burnable/non-flammable liquid. It was formerly used as a flame retardant, a solvent for fats and waxes and because
of its high density for mineral separation. Now, it is only used as a reagent or intermediate in organic chemistry. Small amounts of BDCM are also made in chemical plants for
use in laboratories or in making other chemicals. On contact with hot surfaces or flames,
BDMC decomposes forming toxic and corrosive gases, including hydrogen bromide and
hydrogen chloride and reacts with strong bases, strong oxidants, and magnesium. BDMC
is found in chlorinated drinking water as a consequence of the reaction between chlorine,
added during water treatme | [General Description]
Clear colorless liquid. | [Reactivity Profile]
DICHLOROBROMOMETHANE(75-27-4) may react with strong bases and magnesium. Incompatible with oxidizing materials . | [Air & Water Reactions]
Slightly water soluble. | [Health Hazard]
On ingestion, BDMC causes damage to the kidneys, liver, and impaired functio | [Health Hazard]
SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, mucous membranes and respiratory tract. It may also cause narcosis. Other symptoms may include nausea, dizziness and headache. It may also cause liver and kidney damage. Central nervous system effects may also occur. | [Fire Hazard]
Literature sources indicate that this chemical is nonflammable. | [Description]
Bromodichloromethane is a liquid. Molecularweight=163.8; Specific gravity (H2O:1)=1.98; Boilingpoint=90℃. Odor threshold=about 1675 mg/m3. Solublein water. | [Uses]
A volatile halogenated methane present in trace amounts in drinking water as a result of the water treatment process. It is also present in swimming pools due to chlorination and can be used as tracers to identify water leaks. It is useful as chain transfer agents in PVC polymerization. | [Uses]
As a chemical intermediate for organic
synthesis and as a laboratory reagent; formerly
used as a solvent and flame retardant.
Currently, the major source of bromodichloromethane
in the environment is from its formation as a by-product during chlorination
of water. | [Uses]
Chemical reagent, intermediate in organic synthesis. | [Definition]
ChEBI: A one-carbon compound that is methane substituted by a bromo and two chloro groups. It occurs as a contaminant in drinking water. | [Synthesis Reference(s)]
Tetrahedron Letters, 28, p. 2769, 1987 DOI: 10.1016/S0040-4039(00)96205-1 | [Biochem/physiol Actions]
Bromodichloromethane (BDCM) induces steatohepatitic injury in human liver. BDCM induces the cell proliferation in different tissues and kidney damage by renal tuble cell proliferation in male F344 rats. | [Potential Exposure]
This compound may find applicationin organic synthesis. | [First aid]
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contactsthe skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove fromexposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing hasstopped and CPR if heart action has stopped. Transferpromptly to a medical facility. When this chemical hasbeen swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. | [Carcinogenicity]
Bromodichloromethane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. | [Source]
MCLG: zero; MCL: 0.08 mg/L. Total for all trihalomethanes
cannot exceed a concentration of 0.08 mg/L. In addition, a DWEL of 700 μg/L was recommended
(U.S. EPA, 2000).
By-product in chlorination of drinking water and use of fire extinguishers (quoted,
Verschueren, 1983). | [Environmental Fate]
Biological. Bromodichloromethane showed significant degradation with gradual adaptation in a
static-culture flask-screening test (settled domestic wastewater inoculum) conducted at 25 °C. At
concentrations of 5 and 10 mg/L, percent losses after 4 wk of incubation were 59 and 51,
respectively. At a substrate concentration of 5 mg/L, 8% was lost due to volatilization after 10 d
(Tabak et al., 1981).
Chemical/Physical. The estimated hydrolysis half-life in water at 25 °C and pH 7 is 137 yr
(Mabey and Mill, 1978). Reported products of hydrolysis include carbon monoxide, hydrochloric
and hydrobromic acids (Ellington et al., 1993; Kollig, 1993).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities at
pH 5.3 were 7.9, 1.9, 0.47, and 0.12 mg/g, respectively (Dobbs and Cohen, 1980). | [storage]
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in a refrigerated space in a tightly closedcontainer. Protect from light. A regulated, marked areashould be established where this chemical is handled,used, or stored in compliance with OSHA Standard1910.1045. | [Shipping]
Toxic, liquids, organic, n.o.s. requires a shippinglabel of “POISONOUS/TOXIC MATERIALS.” It falls intoHazard Class 6.1 and Packing Group III. |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,F | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R40:Limited evidence of a carcinogenic effect.
R41:Risk of serious damage to eyes.
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/39:Wear suitable protective clothing and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves .
S16:Keep away from sources of ignition-No smoking .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
2810 | [WGK Germany ]
3
| [RTECS ]
PA5310000
| [F ]
8 | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29037990 | [Safety Profile]
Confirmed carcinogen
with experimental carcinogenic data.
Moderately toxic by ingestion. Human
mutation data reported. When heated to
decomposition it emits very toxic fumes of
Brand Cl-. See also CHLORINATED
HYDROCARBONS, ALIPHATIC; and
BROMIDES. | [Hazardous Substances Data]
75-27-4(Hazardous Substances Data) | [Toxicity]
LD50 in male, female mice (mg/kg): 450, 900 orally (Bowman) |
|
| Company Name: |
Alfa Aesar
|
| Tel: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|