| Identification | More | [Name]
6-ANILINO-5,8-QUINOLINEDIONE | [CAS]
91300-60-6 | [Synonyms]
LY 83583
91300-60-6
LY-83583
(LY83583)
6-ANILINO-5,8-QUINOLINEDIONE
6-ANILINO-5,8-QUINOLINEQUINONE
6-ANILINOQUINOLINE-5,8-QUINONE
6-(anilino)quinoline-5,8-dione
6-(phenylamino)quinoline-5,8-dione
6-(PHENYLAMINO)-5,8-QUINOLINEDIONE
LY 83583 - CAS 91300-60-6 - Calbiochem
5,8-Dihydro-5,8-dioxo-6-(phenylaMino)quinoline
6-(Phenylamino)-5,8-quinolinedione, LY-83,583
(4-methyl-2-oxo-1-benzopyran-7-yl)oxy-phenylphosphinic acid
5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline, [(5,8-Dihydro-5,8-dioxoquinolin-6-yl)amino]benzene, 6-Anilinoquinoline-5,8-dione | [Molecular Formula]
C15H10N2O2 | [MDL Number]
MFCD00210756 | [Molecular Weight]
250.25 | [MOL File]
91300-60-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Red-Brown Solid | [Melting point ]
184-185°C | [storage temp. ]
2-8°C
| [solubility ]
0.1 M HCl: 1 mg/mL
| [form ]
solid
| [color ]
violet
| [Usage]
Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release | [CAS DataBase Reference]
91300-60-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
2
| [HS Code ]
2933499090 |
| Hazard Information | Back Directory | [Chemical Properties]
Red-Brown Solid | [Uses]
Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release | [Uses]
Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2μM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release. | [Uses]
LY83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC50 value of 2 μM. LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 μM and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki value of 3 μM.[Cayman Chemical] | [Definition]
ChEBI: A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group. |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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