| Identification | More | [Name]
Fotemustine | [CAS]
92118-27-9 | [Synonyms]
1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea
FOTEMUSTINE
Fotemustin
Phosphonic acid, P-[1-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-, diethyl ester
[1-[[[(2-Chloroethyl)nitlx~amino]carbonyl]amino]ethyl]phosphonic acid diethyl ester
Muphoran
S-10036
[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]phosphonic acid diethyl ester | [Molecular Formula]
C9H19ClN3O5P | [MDL Number]
MFCD00866278 | [Molecular Weight]
315.69 | [MOL File]
92118-27-9.mol |
| Hazard Information | Back Directory | [Description]
Fotemustine is a new nitrosourea reportedly effective in the treatment of disseminated
malignant melanoma, with only mild hematological toxicity. Response rate is generally
lower in patients with colonic, breast, head and neck cancer. | [Originator]
Servier (France) | [Uses]
Fotemustine is used in patients malignant gliomas to improve the efficacy of radiotherapy. Used in the treatment of glioblastomas. | [Definition]
ChEBI: Diethyl (1-{[(2-chloroethyl)(nitroso)carbamoyl]amino}ethyl)phosphonate is a member of the class of N-nitrosoureas that is ethyl diethylphosphonate in the hydrogen at position 1 of the ethyl group attached to the phosphorus has been replaced by a [(2-chloroethyl)(nitroso)carbamoyl]amino group. It is an organic phosphonate, a member of N-nitrosoureas and an organochlorine compound. | [Brand name]
Muphoran |
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| Company Name: |
LGM Pharma
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| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
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