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548-77-6

中文名称 鸢尾苷
英文名称 Tectorigenin
CAS 548-77-6
分子式 C16H12O6
分子量 300.26
MOL 文件 548-77-6.mol
更新日期 2024/04/22 10:34:58
548-77-6 结构式 548-77-6 结构式

基本信息

中文别名
射干苷元
鸢尾黄酮
鸢尾苷元磺酸钠
鸢尾黄素对照品,
鸢尾黄素(鸢尾黄酮
鸢尾黄素(标准品)
鸢尾黄酮,鸢尾苷元,射干苷元
TECTORIGENIN 鸢尾黄素
HEPA1-6[HEPA1-6]说明书
鸢尾黄素(鸢尾黄酮,鸢尾苷元,射干苷元)
英文别名
Tectrigenin
Tectorigenine
4',5,7-Trihydroxy-6-methoxyisoflavone
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromone
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-
Tectorigenin 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
所属类别
生物化工:提取物

物理化学性质

外观性状淡黄色结晶,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于植物射干的根茎。
熔点225-226°
沸点361.5°C (rough estimate)
密度1.512
折射率1.4600 (estimate)
储存条件2-8°C
溶解度DMSO : 150 mg/mL (499.57 mM; Need ultrasonic and warming)
酸度系数(pKa)6.49±0.20(Predicted)
形态粉末晶体
颜色白色至橙色再至绿色
BRN305601
CAS 数据库548-77-6

安全数据

危险性符号(GHS)
GHS07
警示词警告
危险性描述H302
WGK Germany3
RTECS号NR2400000
海关编码2932.99.6100

应用领域

用途1
射干苷元具有抗病毒、抗炎、解热和镇痛的作用。

图谱信息

鸢尾苷价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/01/16T3729鸢尾苷
Tectorigenin
548-77-610mg270元
2024/01/16T3729鸢尾苷
Tectorigenin
548-77-650mg990元

常见问题列表

生物活性
Tectorigenin 是一种植物异黄酮,最初是从葛根汤干燥的花中分离出来的。
体外研究

Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth. Palmitic acid (PA)-stimulated ROS production is abolished by treatment with Tectorigenin for HUVECs in a dose-dependent manner (0.1, 1, 10 μM). Treatment with Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. Tectorigenin treatment also effectively inhibits PA-augmented TNF-α and IL-6 production in a concentration dependent manner. The number of viable HepG2 cells treated by Tectorigenin decreases in a concentration- and time-dependent manner. When HepG2 cells are treated with Tectorigenin at 5, 10 and 20 mg/L for 24 h, the viability rate is 91%, 79% and 62%, respectively.

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