88150-62-3
中文名称
邻苯二甲酰基氨氯地平
英文名称
Phthaloyl amlodipine
CAS
88150-62-3
EINECS 编号
413-410-3
分子式
C34H33ClN2O10S
MDL 编号
MFCD07782096
分子量
697.15
MOL 文件
88150-62-3.mol
更新日期
2024/04/16 11:06:54
88150-62-3 结构式
基本信息
中文别名
安氯地平中间体4-(2-氯苯基)-3-乙氧羰基-5-甲氧羰基-6-甲基-2-(酞酰亚氨基乙氧基)甲基-1,4-二氢吡啶
邻苯二甲酰基氨氯地平
英文别名
3-ETHYL-5-METHYL-4-(2-CHLOROPHENYL)-2-(2-PHTHALIMIDOETHOXY)METHYL-6-METHYL-1,4-DIHYDRO-PYRIDINE-3,5-DICARBOXYLATEAMLODIPINE INTERMEDIATE
PHTHALOYL AMLODIPINE
3-Ethyl-5-methyl-4-(2-Chlorophenyl)-2-(2-phthalimidoethoxl)-methyl-6-methyl-1,4-dihydropyridine-3,5-Dicarboxylate
3-Ethyl-5-Methyl-4-(2-Chlorophenyl)-2-(2-Phthalimidoethoxy)Methyl-6-Methyl-1,4-Dihydro-Pyridine-3,5-Didarboxylate
3-Ethyl-5-Methyl-4-(2-Chlorophenyl)-2-(2-Phthalimidoethoxy)Methyl-6-Methyl-1,4-Dihydro-Pyridine-3,5-Dicarboxylate
3-Ethyl-5-methyl-4-(2-chlorophenyl)-2-(2-phthalimidoethoxyl)methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-(phthalimidoethoxy)methyl-1,4-dihydropyridine
Phthalimidoamlodipine
3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
熔点140-145°C
沸点654.1±55.0 °C(Predicted)
密度1.321±0.06 g/cm3(Predicted)
储存条件Sealed in dry,Room Temperature
溶解度可溶于DMSO（轻微）、甲醇（轻微、加热和超声处理）
酸度系数(pKa)2.06±0.70(Predicted)
形态neat
颜色淡黄色至淡黄色
PH值6.78 at 20.4℃ and 10g/L
LogP4.9 at 30℃ and pH6.79