醋酸烯诺孕酮
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- CAS号:
- 7759-35-5
- 英文名:
- Nestoron
- 英文别名:
- ST 1435;NESTORON;NESTORONE;Elcometrine;Nestorone Acetate;Nestoron (ST-1435);Norgestone acetate;Segesterone Acetate;ELCOMETRINE;NESTORONE;ST-1435;ST1435;ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435
- 中文名:
- 醋酸烯诺孕酮
- 中文别名:
- 醋酸烯诺孕酮;烯诺孕酮醋酸酯;醋酸烯诺孕酮(ST-1435)
- CBNumber:
- CB31011778
- 分子式:
- C23H30O4
- 分子量:
- 370.48
- MOL File:
- 7759-35-5.mol
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醋酸烯诺孕酮化学性质
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熔点:
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178-179°
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比旋光度:
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D21 -105° (c = 1.2 in chloroform)
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沸点:
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420.37°C (rough estimate)
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密度:
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1.0550 (rough estimate)
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折射率:
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1.4433 (estimate)
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储存条件:
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2-8°C
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溶解度:
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DMSO: soluble5mg/mL, clear
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形态:
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powder
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颜色:
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white to beige
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InChIKey:
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CKFBRGLGTWAVLG-GOMYTPFNSA-N
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醋酸烯诺孕酮性质、用途与生产工艺
Nestoron (ST-1435) 是一种 19-norprogesterone 衍生物，对 progesterone receptors 具有高亲和力和选择性，是一种高度选择性和有效的孕激素，可用作激素避孕药。
Nestoron (400 μCi
3
H Nestoron/kg BW; subcutaneous injection; female Sprague-Dawley rats) treatment results in the C
max
in the blood and plasma are 58.1 and 95.5 ng equiv.
3
H Nestoron/g, with t
1/2
of 15.6 hours. Approximately, 81.4% and 7.62% of the administered dose is excreted via feces and urine, respectively.
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Animal Model:
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27 adult, female, Sprague-Dawley rats (200-225 g; age: 8 weeks)
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Dosage:
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400 μCi
3
H Nestorone/kg BW
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Administration:
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Subcutaneous injection (Pharmacokinetic study)
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Result:
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The mean peak concentrations of radioactivity (C
max
) in the blood and plasma were 58.1 and 95.5 ng equiv./g, with t
1/2
of 15.6 hours. Approximately, 81.4% and 7.62% of the administered dose was excreted via feces and urine, respectively.
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醋酸烯诺孕酮
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-13071 | Nestoron | | 5 mg | 375元 |
| 2024/01/25 | HY-13071 | 醋酸烯诺孕酮
Nestoron | 7759-35-5 | 10mg | 600元 |
7759-35-5, 醋酸烯诺孕酮 相关搜索:
- API
- 原料药
- 生物化工
- 烯诺孕酮醋酸酯
- 醋酸烯诺孕酮(ST-1435)
- 醋酸烯诺孕酮
- 7759-35-5
- Nestorone Acetate
- ST 1435,Inhibitor,Nestoron,ST1435,inhibit,Progesterone Receptor,NR3C3
- Norgestone acetate
- Estr-4-en-3-one,17-acetyl-17-(acetyloxy)-16-methylene-,(17α)-
- 19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene-
- ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435
- (8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylene-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
- Segesterone Acetate
- ELCOMETRINE;NESTORONE;ST-1435;ST1435
- 17-(Acetyloxy)-16-methylene-19-norpregn-4-ene-3,20-dione
- Nestoron (ST-1435)
- 19-Norpregn-4-ene-3,20-dione, 17-hydroxy-16-methylene-, acetate
- 19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene- (9ci)
- 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione
- 16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate
- 17-(ACETYLOXY)-16-METHYLENE-19-NORPREGN-4-ENE-20-DIONE
- Elcometrine
- 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate
- NESTORON
- NESTORONE
- ST 1435