1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

This alkaloid has recently been shown to exhibit a marked antineoplastic activity. Administration of 25 or 50 mg/kg intraperitoneally on alternate days or daily until death to mice which had been inoculated with a single intraperitoneal dose of 106 -102 LI2l0 leukemia cells increased the survival time by 89-229 per cent compared with control animals.
Japanese workers have recently reported the synthesis of olivacine by heating indole with 4(1-hydroxyethyl)-3-methoxymethyl-2-methylpyridine in 47 per cent HBr.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 27, p. 1751, 1990 DOI: 10.1002/jhet.5570270645

Einzelnachweise

Regina et al., Cienc. Cult. (Sao Paulo), 26, 517 (1974)
Synthesis: Kametani et al., J. Chern. Soc., Perkin I, 2102 (1975)

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3421	58

484-49-1()Verwandte Suche:

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• 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE
• OLIVACINE
• Olivacin
• 6H-Pyrido[4,3-B]carbazole, 1,5-dimethyl-
• Inchi=1/C17H14N2/C1-10-12-7-8-18-11(2)14(12)9-15-13-5-3-4-6-16(13)19-17(10)15/H3-9,19H,1-2h
• 484-49-1
• Indoles and derivatives