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1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE structure

CAS No.: 484-49-1

Chemical Name:: 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE

Synonyms: Olivacin;OLIVACINE;1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;6H-Pyrido[4,3-B]carbazole, 1,5-dimethyl-;Inchi=1/C17H14N2/C1-10-12-7-8-18-11(2)14(12)9-15-13-5-3-4-6-16(13)19-17(10)15/H3-9,19H,1-2h

CBNumber:: CB0434720

Molecular Formula:: C17H14N2

Molecular Weight:: 246.31

MDL Number:: MFCD00189403

MOL File:: 484-49-1.mol

Last updated:2023-05-13 08:28:58

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1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Properties

Melting point	317-325°
FDA UNII	5WSL5LL2C3

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	PXT0001308	1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE 98.00%	484-49-1	25MG	$1372.14	2021-12-16	Buy
AHH	MT-11009	1,5-Dimethyl-6H-pyrido[4,3-b]carbazole 99%	484-49-1	1000g	$495	2021-12-16	Buy

Product number	Packaging	Price	Buy
PXT0001308	25MG	$1372.14	Buy
MT-11009	1000g	$495	Buy

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Chemical Properties,Uses,Production

Description

This alkaloid has recently been shown to exhibit a marked antineoplastic activity. Administration of 25 or 50 mg/kg intraperitoneally on alternate days or daily until death to mice which had been inoculated with a single intraperitoneal dose of 106 -102 LI2l0 leukemia cells increased the survival time by 89-229 per cent compared with control animals.
Japanese workers have recently reported the synthesis of olivacine by heating indole with 4(1-hydroxyethyl)-3-methoxymethyl-2-methylpyridine in 47 per cent HBr.

Definition

ChEBI: Olivacine is a member of carbazoles.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 27, p. 1751, 1990 DOI: 10.1002/jhet.5570270645

References

Regina et al., Cienc. Cult. (Sao Paulo), 26, 517 (1974)
Synthesis: Kametani et al., J. Chern. Soc., Perkin I, 2102 (1975)

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE synthesis

Synthesis of 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE from 1H-Pyrido[4,3-b]carbazole, 2,6-dihydro-1,5-dimethyl-2-[(4-methylphenyl)sulfonyl]-

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Preparation Products And Raw materials

Raw materials

1H-Pyrido[4,3-b]carbazole, 2,6-dihydro-1,5-dimethyl-2-[(4-methylphenyl)sulfonyl]- Acetamide,N-[2-(1-methyl-9H-carbazol-2-yl)ethyl]-

Preparation Products

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3421	58

Supplier	Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd.	58

484-49-1(1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE)Related Search:

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1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE OLIVACINE Olivacin 6H-Pyrido[4,3-B]carbazole, 1,5-dimethyl- Inchi=1/C17H14N2/C1-10-12-7-8-18-11(2)14(12)9-15-13-5-3-4-6-16(13)19-17(10)15/H3-9,19H,1-2h 484-49-1 Indoles and derivatives