Ethisteron
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- CAS-Nr.
- 434-03-7
- Bezeichnung:
- Ethisteron
- Englisch Name:
- Ethisterone
- Synonyma:
- Progestoral;17A-ETHYNYLTESTOSTERONE;Prone;Pranone;Pregnin;Gestoral;NSC-9565;Prodoxan;Produxan;Prolutol
- CBNumber:
- CB1207877
- Summenformel:
- C21H28O2
- Molgewicht:
- 312.45
- MOL-Datei:
- 434-03-7.mol
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Ethisteron Eigenschaften
- Schmelzpunkt:
- 263-269 °C (lit.)
- alpha
- D23 +23.8° (dioxane); D25 -32.0° (pyridine)
- Siedepunkt:
- 392.36°C (rough estimate)
- Dichte
- 1.0697 (rough estimate)
- Brechungsindex
- 33 ° (C=1, Pyridine)
- storage temp.
- room temp
- Löslichkeit
- Soluble to 0.05 mg/mL
(0.16 mM) in DMSO
- pka
- 13.10±0.60(Predicted)
- Wasserlöslichkeit
- soluble in chloroform, DMSO (0.05 mg/ml), acetone (slightly ), ethanol (<1 mg/ml at 25°C), and water (<1 mg/ml at 25°C).
- Merck
- 14,3741
- BRN
- 1889895
- InChIKey
- CHNXZKVNWQUJIB-CEGNMAFCSA-N
- CAS Datenbank
- 434-03-7
- NIST chemische Informationen
- Ethisterone(434-03-7)
Ethisteron Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R40:Verdacht auf krebserzeugende Wirkung.
R48:Gefahr ernster Gesundheitsschäden bei längerer Exposition.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Ethisterone is an orally bioavailable synthetic progestin and a derivative of testosterone (Item Nos.
ISO60154 |
15645) that binds to progesterone and androgen receptors (EC
50s = 23 and 23.1 nM, respectively, in yeast). Ethisterone (1 μM) downregulates progesterone receptors in MCF-7 cells.
Chemische Eigenschaften
Off-White Powder
Verwenden
Ethisterone has been used as a component in Dulbecco′s modified eagle medium (DMEM) to culture the transfected COS-7 cell for transient transfection assay and?gene transfection assay.
Definition
ChEBI: A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol.
Allgemeine Beschreibung
Ethisterone is a?progestogen. It is a danazol derivative.
Ethisteron Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
17-ethyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Ethisteron Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 336)Lieferanten
434-03-7(Ethisteron)Verwandte Suche:
Testosteron
4'-Hydroxyacetophenon
3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacy-clotetradecin-1,7(8H)-dion,(S-(E))-
Quinocetone
Androst-4-en-3,17-dion
3,6-Bis[(4-chlor-2-phosphonophenyl)azo]-4,5-dihydroxynaphthalin-2,7-disulfonsure
2'-Hydroxyacetophenone
Clethodim
Gestrinone
Norgestrel
6-Methylhept-5-en-2-on
Norethisteron
Acetylen
Progesteron
Dimethisteron
Ethisteron
- 4,17ALPHA-PREGNEN-17BETA-OL-20-YN-3-ONE
- 4,17a-pregnen-17b-ol-20-yn-3-one
- 4,17A-PREGNEN-17B-OL-20-YNE
- 4-ANDROSTEN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE
- (8R,9S,10R,13S,14S,17R)-17-ETHYNYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
- ANHYDROHYDROXYPROGESTERONE
- ANHYDROXYPROGESTERONE
- 17BETA-HYDROXY-4,17ALPHA-PREGNEN-20-YN-3-ONE
- 17b-hydroxy-4,17a-pregnen-20-yn-3-one
- (8R,9S,10R,13S,14S,17S)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
- 17A-ETHYNYL-4-ANDROSTEN-17B-OL-3-ONE
- 17a-ethynyl-17b-hydroxy-4-androsten-3-one
- 17ALPHA-ETHYNYLTESTOSTERONE
- 17α-Ethynyltestosterone, 17β-Hydroxy-4,17α-pregnen-20-yn-3-one, 4,17α-Pregnen-17β-ol-20-yn-3-one
- (8R,9S,10R,13S,14S,17R)-17-ETHYNYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHY
- ETHISTERONE(RG)
- Ethisterone,17α-Ethynyltestosterone, 17β-Hydroxy-4,17α-pregnen-20-yn-3-one, 4,17α-Pregnen-17β-ol-20-yn-3-one
- ETHISTERONE(RG)(CALL)
- Ethisterone 0
- (17α)-17-hydroxy-pregn-4-en-20-yn-3-one
- ETHINYL TESTOSTERONE
- ETHISTERONE
- ETHYNYLTESTOSTERONE
- ETHYNYLANDROSTENOLONE
- (17-alpha)-pregn-4-en-20-yn-3-on
- Gestoral
- Lucorteum Oral
- lucorteumoral
- Lutidon Oral
- lutidonoral
- Lutocyclin
- Lutocyclol
- Lutocylol
- Nalutoral
- NSC-9565
- Nugestoral
- Ora-Lutin
- Pranone
- Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-
- Pregneninolone
- Pregnin
- Primolut C
- primolutc
- Prodoxan
- Prodroxan
- Produxan
- Progestab
- Progestin P
- progestinp
- Progestolets
- Prolutol
- Proluton C
- 17-alpha-ethinyltestosterone
- 17alpha-Ethynyl-17beta-hydroxyandrost-4-en-3-one
- 17alpha-Pregn-4-en-20-yn-3-one, 17-hydroxy-
- 17-beta-Hydroxy-17-alpha-ethynyl-4-androsten-3-one
- 17-Ethinyltestosterone
- 17-Ethynyl-17beta-hydroxyandrost-4-en-3-one
