SR3335

293753-05-6

CAS-Nr.: 293753-05-6

Englisch Name:: SR3335

Synonyma:: ML-176;SR3335;SR3335;ML176;ML-176;SR-3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR 3335 (This product is only available in Japan.);N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide;N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide;2-Thiophenesulfonamide, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-

CBNumber:: CB12628427

Summenformel:: C13H9F6NO3S2

Molgewicht:: 405.3358792

MOL-Datei:: 293753-05-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 74

SR3335 Eigenschaften

storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Löslichkeit: insoluble in H2O; ≥87.4 mg/mL in EtOH; ≥88.8 mg/mL in DMSO

Aggregatzustand: solid

Sicherheit

SR3335 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (K_i = 220 nM) and inhibiting constitutive transactivation activity (IC₅₀ = 480 nM). It is without effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis.

SR3335 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE 2-Thiophenesulfonyl chloride Anilin

Downstream Produkte

SR3335 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 74)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	sales@meilune.com	China	4654	58

SR3335
SR3335,Thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide
ML-176
N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide
hiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide
ML-176;SR-3335
SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176
SR3335;ML176
SR 3335 (This product is only available in Japan.)
Thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide
ML-176;SR 3335;SR-3335;ML176;ML 176
2-Thiophenesulfonamide, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-
N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide
293753-05-6
C13H9F6NO3S2