9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat
|
|
|
- CAS-Nr.
- 2152-44-5
- Bezeichnung:
- 9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat
- Englisch Name:
- Betamethasone 17-valerate
- Synonyma:
- BETAMETHASONE VALERATE;VALISONE;Betaderm;BETNOVATE;BETHAMETASONE VALERATE;Luxiq;Betoid;Valison;9α-Fluo;Deviphos
- CBNumber:
- CB1317879
- Summenformel:
- C27H37FO6
- Molgewicht:
- 476.58
- MOL-Datei:
- 2152-44-5.mol
|
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Eigenschaften
- Schmelzpunkt:
- 183-184°
- alpha
- D +77° (dioxane)
- Siedepunkt:
- 598.9±50.0 °C(Predicted)
- Dichte
- 1.1174 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- Practically insoluble in water, freely soluble in acetone and in methylene chloride, soluble in ethanol (96 per cent).
- pka
- 12.90±0.70(Predicted)
- Farbe
- White
- Merck
- 13,1183
- BRN
- 4240001
- InChIKey
- SNHRLVCMMWUAJD-SUYDQAKGSA-N
- SMILES
- [C@]12(C)C[C@@H]([C@]3(F)[C@@]4(C)C=CC(=O)C=C4CC[C@@]3([H])[C@]1([H])C[C@H](C)[C@@]2(C(=O)CO)OC(=O)CCCC)O |&1:0,3,4,6,16,18,21,23,r|
- CAS Datenbank
- 2152-44-5(CAS DataBase Reference)
- EPA chemische Informationen
- .beta.-Methasone 17-valerate (2152-44-5)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
|
|
| R-Sätze: |
48 |
|
|
| S-Sätze: |
22-24/25 |
|
|
| RTECS-Nr. |
TU3835000 |
|
|
| HS Code |
2937229000 |
|
|
| Toxizität |
mouse,LD50,intraperitoneal,632mg/kg (632mg/kg),Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H373 |
Kann die Organe schädigen bei längerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizität (wiederholte Exposition) |
Kategorie 2 |
Warnung |
|
P260, P314, P501 |
|
| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
|
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R48:Gefahr ernster Gesundheitsschäden bei längerer Exposition.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White Solid
Definition
ChEBI: Betamethasone valerate is a steroid ester that is betamethasone in which the hydroxy group at the 17alpha position has been converted to the corresponding pentanoate ester. It has a role as an anti-inflammatory drug. It is a steroid ester, a 20-oxo steroid, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a primary alpha-hydroxy ketone. It is functionally related to a betamethasone.
Indications
Betamethasone valerate (Psorion, Beta-Val, Luxiq) is a synthetic fluorinated corticosteroid.
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 535)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Nanjing Shizhou Biotechnology Co., Ltd
|
+86-15850508050 +86-15850508050
|
sean.lv@synzest.com |
China |
323 |
58 |
|
Hebei Kangcang new material Technology Co., LTD
|
+8619133911216
|
fanfan@kangcang.com.cn |
China |
340 |
58 |
|
Hebei Mojin Biotechnology Co., Ltd
|
+8613288715578
|
sales@hbmojin.com |
China |
12456 |
58 |
|
Wuhan Haorong Biotechnology Co.,ltd
|
+8618565342920
|
sales@chembj.net |
China |
269 |
58 |
|
Henan Fengda Chemical Co., Ltd
|
+86-371-86557731 +86-13613820652
|
info@fdachem.com |
China |
7845 |
58 |
|
Shaanxi TNJONE Pharmaceutical Co., Ltd
|
+8618740459177
|
sarah@tnjone.com |
China |
893 |
58 |
|
Frapp's ChemicalNFTZ Co., Ltd.
|
+86 (576) 8169-6106
|
sales@frappschem.com |
China |
885 |
50 |
|
Beijing Cooperate Pharmaceutical Co.,Ltd
|
010-60279497
|
sales01@cooperate-pharm.com |
CHINA |
1811 |
55 |
|
Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
|
info@tianfuchem.com |
China |
21691 |
55 |
|
Hubei XinRunde Chemical Co., Ltd.
|
+8615102730682
|
bruce@xrdchem.cn |
CHINA |
566 |
55 |
2152-44-5(9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat)Verwandte Suche:
Dimagnesiumtrisiliciumoctaoxid
Beclometason
Trichlorethylen
Thiophanat-methyl
Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, Dinatriumsalz, (11β,16β)-
HT-2 TOXIN
Betamethason
Methyl
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
9-Chlor-11β-hydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-dipropionat
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-21-(hydrogenphosphonat)
17,21-Dihydroxy-16β-methylpregna-1,4,9(11)-trien-3,20-dion
Brommethan
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(valerat)
Fluor
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat
- pregna-1,4-diene-3,20-dione,9-fluoro-11,21-dihydroxy-16-methyl-17-((1-oxopenty
- 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-valerate
- 9ALPHA-FLUORO-16BETA-METHYLPREDNISOLONE 17-VALERATE
- 9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 17-VALERATE
- 1,4-PREGNADIENE-11BETA,17ALPHA,21-TRIOL-9ALPHA-FLUORO-16BETA-METHYL-3,20-DIONE 17-VALERATE
- 1,4-pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate
- 9α-Fluoro-16β-methylprednisolone 17-valerate, Betnovate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17-valerate, 1,4-Pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate
- BetaMethasone valerate (Betnovate)
- BetaMethasone Valerate, Micronized USP
- Deviphos
- Phosphanylidenezinc zinc
- Valison
- [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
- [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyethanoyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
- valeric acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-17-glycoloyl-11-hydroxy-3-keto-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester
- Betamethasone 17-valerate,1,4-Pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17-valerate, 9α-Fluoro-16β
- Betamethasone Valerate (200 mg)
- Betamethasone Valerate (200 mg)K0C3300.997mg/mg(ai)
- Betamethasone 17-val
- BetaMethasone valerate (Betnovate, Celestone)
- (11β,16β)-9-Fluoro-11,21-dihydroxy-16-Methyl-17-[(1-oxopentyl)oxy]pregna-1,4-diene-3,20-dione
- 9α-Fluo
- 9α-Fluoro-16β-Methylprednisolone 17-Valerate
- (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-triMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate
- BetaMethasone valerate 17-
- betnovateat
- celestoderm
- 1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17-VALERATE
- BEDERMIN
- BETNESOL-V
- BETNEVAL
- BETAMETHASONE 17ALPHA-VALERATE
- BETAMETHASONE 17A-VALERATE
- BETAMETHASONE 17-VALERATE
- BETAMETHASONEVALERATE,MICRONIZEDPOWDER,USP
- 9α-Fluoro-11β,21-dihydroxy-16β-methyl-17α-valeryloxypregna-1,4-diene-3,20-dione
- Beta-Val
- Betoid
- Bextasol
- Celestan V
- Celestane V
- Celestoderm V
- Celeston valerate
- Dermosol
- Dermovaleas
- Ecoval 70
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17-valerate (7CI, 8CI)
- Rinderon V
- Stanoval
- Tokuderm
- Valeric acid, 17-ester with 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (8CI)
- betamethasone pentanoate
- 1,4-pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate
- BETAMETHASONE 17-VALERATE VETRANAL, 250
- BETAMETHASONE 17-VALERATE BP USP
- BETAMETHASONE VALERATE BP STANDARD(CRM STANDARD)
- BETAMETHASONE VALERATE USP(CRM STANDARD)
- BETAMETHASONE VALERATE WHO(CRM STANDARD)
