N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin
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- CAS-Nr.
- 458-24-2
- Bezeichnung:
- N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin
- Englisch Name:
- FENFLURAMINE
- Synonyma:
- EQUINE;Acino;Pesos;S-768;C06996;Obedrex;Adipomin;Ponderex;Pondimin;Rotondin
- CBNumber:
- CB1325500
- Summenformel:
- C12H16F3N
- Molgewicht:
- 231.26
- MOL-Datei:
- 458-24-2.mol
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N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Eigenschaften
- Schmelzpunkt:
- 170°C
- Siedepunkt:
- bp12 108-112°
- Dichte
- 1.0950 (estimate)
- storage temp.
- -20°C
- Löslichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Oil
- pka
- pKa 9.10 (Uncertain)
- Farbe
- Colourless to Pale Yellow
- Stabilität:
- Hygroscopic
- CAS Datenbank
- 458-24-2
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P321 |
Besondere Behandlung |
| P330 |
Mund ausspülen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anorexic.
Definition
ChEBI: A secondary amino compound that is 1-phenyl-propan-2-amine in which one of the meta-hydrogens is substituted by trifluoromethyl, and one of the hydrogens attached to the nitrogen is substituted by an ethyl group. It binds to the serotonin reu
take pump, causing inhbition of serotonin uptake and release of serotonin. The resulting increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding
ehavior located in the hypothalamus. This suppresses the appetite for carbohydrates. Fenfluramine was used as the hydrochloride for treatment of diabetes and obesity. It was withdrawn worldwide after reports of heart valve disease and pulmonary hypertensio
.
Weltgesundheitsorganisation (WHO)
Fenfluramine, dexfenfluramine and phentermine were approved
individually more than 20 years ago in the USA for single-drug, short-term
treatment of obesity. The manufacturers of fenfluramine and dexfenfluramine have
since voluntarily withdrawn both products from the market worldwide.
Phentermine remains available.
N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
458-24-2(N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin)Verwandte Suche:
- FENFLURAMINE
- AURORA KA-7683
- AURORA KA-7684
- 1-(meta-Trifluoromethyl-phenyl)-2 ethylaminopropane
- 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine
- Acino
- Adipomin
- N-Ethyl-1-[3-(trifluoromethyl)phenyl]-2-propanamine
- N-Ethyl-alpha-methyl-3-trifluoromethylphenethylamine
- Obedrex
- Pesos
- Phenethylamine, N-ethyl-alpha-methyl-m-(trifluoromethyl)-
- Ponderax PA
- Ponderex
- Pondimin
- Rotondin
- ethyl(alpha-methyl-3-trifluoromethylphenethyl)amine
- FENCLORIN
- N-Ethyl-α-methyl-3-(tfifluoromethyl)benzeneethanamine
- Phenfluoramine
- n-ethyl-alpha-methyl-m-(trifluoromethyl)-phenethylamin
- n-ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine
- Fenfluramin
- N-Ethyl-3-trifluoromethyl-α-methylbenzeneethanamine
- N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine
- N-Ethyl-α-methyl-m-(trifluoromethyl)benzeneethanamine
- dl-Fenfluramine
- C06996
- Methanol(Test Fenfluramine, 1.0 mg/mL)
- Ponderal：Pon-derax
- S-768
- FenfluraMine API
- Fenfluramine solution
- Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-
- FENFLURAMINE USP/EP/BP
- Fenfluramine D6
- EQUINE
- 458-24-2
