illudin M

illudin M Struktur
1146-04-9
CAS-Nr.
1146-04-9
Englisch Name:
illudin M
Synonyma:
illudin M;(3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one;(3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one;Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)-
CBNumber:
CB21385676
Summenformel:
C15H20O3
Molgewicht:
248.32
MOL-Datei:
1146-04-9.mol

illudin M Eigenschaften

Schmelzpunkt:
120-122.5° (Matsumoto); mp 128-130° (McMorris)
Siedepunkt:
452.4±45.0 °C(Predicted)
Dichte
1.24±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
Aggregatzustand
A solid
pka
12.57±0.70(Predicted)

Sicherheit

illudin M Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies.

Verwenden

Illudin M is a cytotoxic sesquiterpene from Omphalotus illudens and Granulobasidium vellereum. It acts as an alkylating agent that can cause inhibition of cell growth or replication.

illudin M Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


illudin M Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 36)Lieferanten
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1146-04-9()Verwandte Suche:


  • illudin M
  • (3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one
  • (3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one
  • Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)-
  • 1146-04-9
  • ADC
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