Sojabohnenoel Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Soybean oil is a clear, pale-yellow colored, odorless or almost odorless liquid, with a bland taste that solidifies between -10 and 16℃. This oil can dissolve in alcohol, ether, chloroform, and carbon disulfide. It is also flammable.
The USP 32 describes soybean oil as the refined fixed oil obtained from the seeds of the soya plant Glycine max Merr. (Fabaceae); if an antoxidant is added, the name and quantity must be specified on the label. The PhEur 6.2 defines refined soybean oil as the fatty oil obtained from the seeds of Glycine soja Sieb. and Zucc. and Glycine max (L.) Merr. (G. hispida (Moench) Maxim.) by extraction and subsequent refining; it may contain a suitable antioxidant. The PhEur 6.2 also includes a monograph for hydrogenated soybean oil. See Vegetable Oil, hydrogenated, type 1.
Verwenden
Soybean Oil is the oil obtained from the seed of the soybean legume. it consists of approximately 86% unsaturated fatty acids with linoleic and oleic being the principal two fatty acids. it exists in hydro- genated and unhydrogenated forms. it is used in shortenings and margarine in the hydrogenated form. it has some use in salad and cooking oils in the unhydrogenated form, but is limited by its tendency to develop undesirable odor and flavor when in contact with air or when heated to frying temperatures. it is also termed soy oil.
Vorbereitung Methode
Obtained by solvent extraction using petroleum hydrocarbons, or
to a lesser extent by expression using continuous screw-press
operations, of the seeds of either Glycine max (Leguminosae) or
Glycine soja (Leguminosae). The oil is refined, deodorized, and
clarified by filtration at about 0℃. Any phospholipids or sterols
present are removed by refining with alkali.
Allgemeine Beschreibung
Pale yellow oily liquid with a weak odor. Floats on water. Contains principally glycerides of oleic and linoleic acids.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
SOYBEAN OIL react with acids to liberate heat. Heat is also generated by interaction with caustic solutions. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Flammable hydrogen is generated by mixing with alkali metals and hydrides. React slowly with oxygen in the air to become rancid.
Health Hazard
None-is a food.
Pharmazeutische Anwendungen
In pharmaceutical preparations, soybean oil emulsions are primarily
used as a fat source in total parenteral nutrition (TPN)
regimens. Although other oils, such as peanut oil, have been
used for this purpose, soybean oil is now preferred because it is
associated with fewer adverse reactions. Emulsions containing
soybean oil have also been used as vehicles for the oral and
intravenous administration of drugs; drug substances that have
been incorporated into such emulsions include amphotericin,
diazepam, retinoids, vitamins, poorly water-soluble steroids, fluorocarbons, ibuprofen, and insulin. In
addition, soybean oil has been used in the formulation of many drug
delivery systems such as liposomes, microspheres, dry
emulsions, self-emulsifying systems, microemulsions,nanoemulsions and nanocapsules, solid-in-oil suspensions, and multiple emulsions.
Soybean oil may also be used in cosmetics and is consumed as an
edible oil. As soybean oil has emollient properties, it is used as a
bath additive in the treatment of dry skin conditions.
Sicherheit(Safety)
Soybean oil is widely used intramuscularly as a drug vehicle or as a
component of emulsions used in parenteral nutrition regimens; it is
also consumed as an edible oil. Generally, soybean oil is regarded as
an essentially nontoxic and nonirritant material. However, serious
adverse reactions to soybean oil emulsions administered parenterally
have been reported. These include cases of hypersensitivity, CNS reactions, and fat embolism. Interference with the
anticoagulant effect of warfarin has also been reported.
Anaphylactic reactions have also been reported following the
consumption of foods derived from, or containing, soybeans.
Recently there has been concern at the concentration of phytoestrogens
in some soy-derived products. Administration of soy protein to
humans has resulted in significantly decreased serum lipid
concentrations.
In 1999, the UK Medical Devices Agency announced the
voluntary withdrawal of a breast implant that contained soybean
oil. The decision was taken because not enough was known at that time about the long-term safety and the rate of breakdown of the
soybean oil in the filling and its possible effects on the body.
LD50 (mouse, IV): 22.1 g/kg
LD50 (rat, IV): 16.5 g/kg
Lager
Soybean oil is a stable material if protected from atmospheric
oxygen.
The formation of undesirable flavors in soybean oil is
accelerated by the presence of 0.01 ppm copper and 0.1 ppm iron,
which act as catalysts for oxidation; this can be minimized by the
addition of chelating agents.
Prolonged storage of soybean oil emulsions, particularly at
elevated temperatures, can result in the formation of free fatty acids,
with a consequent reduction in the pH of the emulsion; degradation
is minimized at pH 6–7. However, soybean oil emulsions are stable
at room temperature if stored under nitrogen in a light-resistant
glass container. Plastic containers are permeable to oxygen and
should not be used for long-term storage since oxidative degradation
can occur.
The stability of soybean oil emulsions is considerably influenced
by other additives in a formulation.
Soybean oil should be stored in a well-filled, airtight, lightresistant
container at a temperature not exceeding 25℃.
Inkompatibilitäten
Soybean oil emulsions have been reported to be incompatible at
25°C with a number of materials including calcium chloride,
calcium gluconate, magnesium chloride, phenytoin sodium, and
tetracycline hydrochloride. Lower concentrations of these
materials, or lower storage temperatures, may result in improved
compatibility. The source of the material may also affect compatibility;
for example, while one injection from a particular
manufacturer might be incompatible with a fat emulsion, an
injection with the same amount of active drug substance from
another manufacturer might be compatible.
Amphotericin B has been reported to be incompatible with
soybean oil containing fat emulsions under certain conditions.
Soybean oil emulsions are also incompatible with many other
drug substances, IV infusion solutions, and ions (above certain
concentrations).
When plastic syringes are used to store soybean oil emulsion,
silicone oil may be extracted into the emulsion; swelling of the
syringe pump also occurs, resulting in the necessity for increased
forces to maintain the motion of the plunger.
Regulatory Status
Included in the FDA Inactive Ingredients Database (IV injections,
oral capsules, and topical preparations). Included in nonparenteral
(chewable tablets; oral capsules; oral lozenges; topical bath
additives) and parenteral (emulsions for IV injection or infusion)
medicines licensed in the UK. Included in the Canadian List of
Acceptable Non-medicinal Ingredients.
Sojabohnenoel Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Lecithins
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ylacetat
Lecithine
le, Pflanzen-, bromiert
Shikonin
SPINOSAD
4-Aminobuttersure
Alkyd enamel
5-(2-Amino-5-O-carbamoyl-2-desoxy-L-xylonamido-1,5-didesoxy-1-(3,4-dihydro-5-hydroxymethyl-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-allofuranuronsure
Stearinsure
C36 Dimer acid
beanaminium trimethyl chloride
Linolsure
Spinosad D
Sojabohnenoel, epoxidiert
Oleic acid
Ethyllinoleat
ETHYL LINOLEATE
Cycloserin
POLYOXIN A
