2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)-
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- CAS-Nr.
- 11024-24-1
- Bezeichnung:
- 2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)-
- Englisch Name:
- DIGITONIN
- Synonyma:
- itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONIN TECH
- CBNumber:
- CB3331307
- Summenformel:
- C56H92O29
- Molgewicht:
- 1229.31
- MOL-Datei:
- 11024-24-1.mol
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2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Eigenschaften
- Schmelzpunkt:
- 230-240 °C (dec.)(lit.)
- Siedepunkt:
- 788.4°C (rough estimate)
- alpha
- D20 -54° (0.45 g in 15.8 ml methanol)
- Dichte
- 1.1421 (rough estimate)
- Brechungsindex
- -52 ° (C=1, EtOH)
- storage temp.
- Sealed in dry,Room Temperature
- Löslichkeit
- H2O: 10 mg/mL at 95 °C hot, clear, colorless
- Aggregatzustand
- White powder
- pka
- 12.68±0.70(Predicted)
- Farbe
- white
- Optische Aktivität
- [α]20/D 54°, c = 2.8 in methanol(lit.)
- Merck
- 14,3161
- BRN
- 78654
- Stabilität:
- Hygroscopic
- InChIKey
- FAAZZWIYYDUONB-JYIJKGCVSA-N
- EPA chemische Informationen
- Digitonin (11024-24-1)
2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
white crystalline powder
Verwenden
Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.
Allgemeine Beschreibung
Crystals or white powder.
Air & Water Reaktionen
Forms soapy aqueous suspension .
Reaktivität anzeigen
DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992
Brandgefahr
Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.
Sicherheitsprofil
Poison by ingestion,
intravenous, intraperitoneal, and
subcutaneous routes. Mutation data
reported. See also DIGITALIS. When
heated to decomposition it emits acrid
smoke and irritating fumes.
läuterung methode
This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]
2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 293)Lieferanten
11024-24-1(2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)-)Verwandte Suche:
2-Octyldodecan-1-ol
2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)-
(5α,25R)-Spirostan-3β-ol
1-[2-(2-Methoxy-1-methylethoxy)-1-methylethoxy]propan-2-ol
1,1-Dimethoxy-2-methylundecan
1,1-Dimethoxydecan
1,1-Dimethoxydodecan
1,1-Diethoxyisooctan
1,1-Diethoxyheptan
5-α-Cholestan
5-α-Cholestan-3-β-ol
1,1-Diethoxyisononan
Undecanal-dimethylacetal
- 25R,5ALPHA-SPIROSTAN-2ALPHA,3BETA,15BETA-TRIOL 3BETA-O-BETA-D-GALACTOPYRANOSYL-(1->3)-O-BETA-D-GALACTYOPYRANOSYL-(1->2)-O-BETA-D-[3-O-BETA-D-XYLOPYRANOSYL]-(1->4)-O-BETA-D-GALACTOPYRANOSIDE
- DIGITONIN CRYSTALLINE
- Digitonin, High Purity
- DIGITONIN (DIGITIN) HIGH PURITY RECEPTOR SOLUBILIZING
- DigitoninGr
- Digitonin, AR
- DIGITONIN, USED AS NON-IONIC DETERGE
- beta.-D-Galactopyranoside, (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1?3)-O-.beta.-D-galactopyranosyl-(1?2)-O-.beta.-D-xylopyranosyl-(1?3)-O-.beta.-D-glucopyranosyl-(1?4)-
- (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1 .beta.-D-Galactopyranoside
- DIGITONIN TECH
- DIGITONIN,CRYSTAL,REAGENT
- DIGITONIN(RG)
- (1→3)]-O-β-D-glucopyranosyl-(1→4)- β-D-
- (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-ylO-.beta.-D-glucopyranosyl-(1.beta.-D-Galactopyranoside
- beta-d-galactopyranoside,(2alpha,3beta,5alpha,15beta,25theta)-2,15-dihyd
- osyl-(1.fwdarw.2)-o-[beta-d-xylopyranosyl-(1.fwdarw.3)]-o-beta-d-glucopyranos
- roxyspirostan-3-ylo-beta-d-glucopyranosyl-(1.fwdarw.3)-o-beta-d-galactopyran
- yl-(1.fwdarw.4)-
- Digitonin ,50%
- 2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl-O-β-D-glucopyranosyl-1β-D-Galactopyranoside
- DIGITIN
- DIGITONIN
- DIGITONIN, ALCOHOL-SOLUBLE
- DIGITONIN WATER SOLUBLE
- Digitogenin,3-[O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-
- galactopyranoside]
- Digitonin, approx. 50% (TLC)
- [(25R)-2α,15β-Dihydroxy-5α-spirostan-3β-yl]4-O-[2-O-[3-O-(β-D-glucopyranosyl)-β-D-galactopyranosyl]-3-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]-β-D-galactopyranoside
- Digitonin, approx. 50% (TLC) 500MG
- Digitonin, approx. 50% (TLC) 5GR
- DIGITONINANALYTICAL GRADE
- DIGITONIN WATER SOLUBLERESEARCH GRADE
- Digitonin,Digitin
- Digitonin, approx. 50%, water soluble
- 5% Digitonin
- Digitonin USP
- itonin
- β-D-Galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-
- Digitonin (Digitin) extrapure, 50%
- 3-Benzoxazole-6-carboxylic acid
- igitonin
- Digitonin (8CI)
- 11024-24-1
- C56H92O29
- C56H92O28
- Sterols
- Lipids
- Non-Ionic
- Detergents
- Conjugates
- Biochemicals and Reagents
- BioChemical
- Surfactants (for Biochemistry)
- Sugars
- Nonionic Surfactants (for Biochemistry)
- Glycosides
- Steroids
- Steroidglycosides
