5-Bromnicotinsaeure
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- CAS-Nr.
- 20826-04-4
- Bezeichnung:
- 5-Bromnicotinsaeure
- Englisch Name:
- 5-Bromonicotinic acid
- Synonyma:
- 5-BROMOPYRIDINE-3-CARBOXYLIC ACID;Nicergoline impurity D CRS;5-BROMO-3-PYRIDINECARBOXYLIC ACID;DF97;AURORA KA-3027;CAS:20826-04-4;AKOS BBS-00007710;5 - broMine niacin;TIMTEC-BB SBB003524;RARECHEM AL BO 0841
- CBNumber:
- CB3375701
- Summenformel:
- C6H4BrNO2
- Molgewicht:
- 202.01
- MOL-Datei:
- 20826-04-4.mol
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5-Bromnicotinsaeure Eigenschaften
- Schmelzpunkt:
- 178-180 °C(lit.)
- Siedepunkt:
- 259.67°C (rough estimate)
- Dichte
- 1.7477 (rough estimate)
- Dampfdruck
- 0.01Pa at 25℃
- Brechungsindex
- 1.6120 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.08±0.10(Predicted)
- Aggregatzustand
- Powder
- Farbe
- White to yellow-gray or light brown
- BRN
- 115854
- InChI
- InChI=1S/C6H4BrNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3H,(H,9,10)
- InChIKey
- FQIUCPGDKPXSLL-UHFFFAOYSA-N
- SMILES
- C1=NC=C(Br)C=C1C(O)=O
- LogP
- 1.17-1.29 at 23.5℃ and pH6.4
- CAS Datenbank
- 20826-04-4(CAS DataBase Reference)
5-Bromnicotinsaeure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Light yellow Cryst
Verwenden
5-Bromopyridine-3-carboxylic acid (5-bromonicotinic acid) was used in the synthesis of 3-guanidinomethyl-5-iodopyridine.
Reaktionen
5-Bromonicotinic acid could used as starting material to synthesize 3-guanidinomethyl-5-iodopyridine. It is also used to prepare four novel multifunctional coordination compounds with different lanthanide(III) ions (Dy, Tb, Yb, and Nd). These materials possess different structures and dimensionalities and show interesting magnetic and luminescence properties, as well as a complete absence of cytotoxicity both in cancer and non-cancer Caco-2 cells[1-2].
läuterung methode
The acid is recrystallised from H2O and then from EtOH using charcoal. The amide has m 219-219.5o (from aqueous EtOH), and the methyl ester, prepared by addition of ethereal diazomethane, can be purified by sublimation in a vacuum and has m 98-99o. The acid chloride also can be sublimed in vacuo and has m 74-75o and gives the methyl ester in MeOH. [Graf J Prakt Chem 138 244 1933, Bachman & Micucci J Am Chem Soc 70 2381 1948, Garcia et al. J Am Chem Soc 82 4430 1960, Misic-Vokovic et al. J Chem Soc 34 1978, Beilstein 22/2 V 181.]
5-Bromnicotinsaeure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Bromnicotinsaeure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 649)Lieferanten
20826-04-4(5-Bromnicotinsaeure)Verwandte Suche:
- RARECHEM AL BO 0841
- TIMTEC-BB SBB003524
- AKOS BBS-00007710
- 3-PYRIDINECARBOXYLIC ACID, 5-BROMO-
- 3-BROMO-5-PYRIDINE CARBOXYLIC ACID
- 3-BROMO PYRIDINE-5-CARBOXYLIC ACID
- 5-BROMONICOTINC ACID
- 5-BROMONICOTINIC ACID
- 5-bromo-3-pyridinecarboxylicaci
- 5-bromo-nicotinicaci
- AURORA KA-3027
- IFLAB-BB F3095-3197
- 5-BromonicotinicAcid98%
- 5-Bromo-3-pyridinecarboxylic
- 5-Bromonicotic acid
- 5-BROMOPYRIDINE-3-CARBOXYLIC ACID / 5-BROMONICOTINIC ACID
- 5-Bromonicotinic acid, 5-Bromopyridine-3-carboxylic acid
- 3-Carboxy-5-bromopyridine
- 5-BROMO NICOTINIC ACID 5-BROMO NICOTINIC ACID
- Nicotinic acid, 5-bromo-
- 5- broMinenicotinic acid
- 5 - broMine niacin
- Nicergoline impurity D
- 5-Bromopyridine-3-carboxylic acid, 3-Bromo-5-carboxypyridine
- 5-Bromopyridine-3-carboxylic acid 98%
- CAS:20826-04-4
- DF97
- 5-Bromonicotinic acid USP/EP/BP
- Nicergoline Impurity 4
- Nicergoline EP Impurity D (5-Bromonicotinic acid)
- 5-Bromonicotinic Acid >
- Nicergoline Impurity 4(Nicergoline EP Impurity D)
- 5-BROMO-3-PYRIDINECARBOXYLIC ACID
- 5-BROMOPYRIDINE-3-CARBOXYLIC ACID
- Nicergoline impurity D CRS
- 5-Bromopyridin-3-carboxylic acid
- 20826-04-4
- Bromopyridines
- Halopyridines
- Building Blocks
- Heterocyclic Building Blocks
- Halogenated Heterocycles
- Pyridines
- Pyridines, Pyrimidines, Purines and Pteredines
- pharmacetical
- Heterocycles
- alkyl bromide|carboxylic acid
- Bromopyridines
- Halopyridines
- Carboxylic Acids
- Pyridine series
- Carboxylic Acids
- Organic acids
- Pyridines derivates
- PROTECTED AMINO ACID & PEPTIDES
- blocks
- Bromides
- Carboxes
