N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE

148672-13-3

CAS-Nr.: 148672-13-3

Englisch Name:: N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE

Synonyma:: CS-2903;GR 127935;GR127935HCl;GR 127935 HYDROCHLORIDE;GR 127935 HYDROCHLORIDE HYDRATE;N-[4-Methoxy-3-(4-methylpiperazin-1-yl)-phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phen;N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE;N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide;N-(4-Methoxy-3-(4-Methylpiperazin-1-yl)phenyl)-2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxaMide;2'-Methyl-4'-(5-methyl-(1,2,4)-oxadiazol-3-yl)biphenyl-4-carboxylic acid (4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)amide

CBNumber:: CB4260019

Summenformel:: C29H31N5O3

Molgewicht:: 497.59

MOL-Datei:: 148672-13-3.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 31

N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE Eigenschaften

Dichte: 1.219±0.06 g/cm3(Predicted)

storage temp.: Sealed in dry,2-8°C

Löslichkeit: H₂O: 14 mg/mL, soluble

pka: 12.55±0.70(Predicted)

Aggregatzustand: solid

Farbe: white

Sicherheit

WGK Germany	3

N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

GR 127935 Hydrochloride Hydrate is a 5-HT1B/1D antagonist used in the treatment of depression and anxiety affecting serotonin levels.

Biologische Aktivität

Potent and selective 5-HT 1B/1D receptor antagonist (pK i values are 8.5 for both guinea pig 5-HT 1D and rat 5-HT 1B receptors). Displays > 100-fold selectivity over 5HT 1A , 5-HT 2A , 5-HT 2C receptors and other receptor types. Centrally active following oral administration.

N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 31)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Chengdu NoVi Biotechnology Co., Ltd.	028-81458053	novibiotech@163.com sales@novi-biotech.com	China	226	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4182	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60

GR 127935 HYDROCHLORIDE
N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride
N-[4-Methoxy-3-(4-methylpiperazin-1-yl)-phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phen
(1,1'-Biphenyl)-4-carboxamide, N-(4-methoxy-3-(4-methyl-1-piperazinyl)phenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-
2'-Methyl-4'-(5-methyl-(1,2,4)-oxadiazol-3-yl)biphenyl-4-carboxylic acid (4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)amide
N-(4-Methoxy-3-(4-Methylpiperazin-1-yl)phenyl)-2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxaMide
N-[4-METHOXY-3-(4-METHYL-1-PIPERAZINYL)PHENYL]-2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)-1,1'-BIPHENYL-4-CARBOXAMIDE HYDROCHLORIDE
N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE
GR 127935 HYDROCHLORIDE HYDRATE
GR127935HCl
N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide
GR 127935
CS-2903
148672-13-3