NSC5844

140926-75-6

CAS-Nr.: 140926-75-6

Englisch Name:: NSC5844

Synonyma:: RE640;RE 640;RE-640;NSC5844;NSC5844 (RE640);NSC 5844; NSC-5844; RE 640; RE-640; RE640;N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine;1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-;NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844

CBNumber:: CB53121123

Summenformel:: C20H16Cl2N4

Molgewicht:: 383.27

MOL-Datei:: 140926-75-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 69

NSC5844 Eigenschaften

Siedepunkt:: 632.6±55.0 °C(Predicted)

Dichte: 1.431±0.06 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMF: 0.33 mg/ml; DMSO: 0.25 mg/ml; Ethanol: slightly soluble

Aggregatzustand: A crystalline solid

pka: 6.61±0.50(Predicted)

Sicherheit

NSC5844 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

NSC 5844 is a bis-quinoline with diverse biological activities. It inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine in vitro (IC₅₀s = 17 and 27 nM, respectively) but lacks activity against P. berghei in vivo. NSC 5844 inhibits the growth of MDA-MB-468 and MCF-7 breast cancer cells with GI₅₀ values of 7.35 and 14.80 μM, respectively. It also inhibits 24% of botulinum neurotoxin serotype A light chain (BoNT/A LC) metalloprotease activity at a concentration of 20 μM.

NSC5844 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

NSC5844 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 69)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	18223	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4604	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2993	58
Grader reagent	18221735425	sales@xinpingchem.com	China	9951	58

140926-75-6()Verwandte Suche:

Chlorbenzol alpha-Cyan-3-phenoxybenzyl-3-(2-chlor-3,3,3-trifluorprop-1-enyl)-2,2-dimethylcyclopropan-carboxylat, 1:1 Gemisch der(Z)-(1R,3R), S-ester und(Z)-(1S,3S), R-ester

NSC5844
N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine
1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-
RE-640
RE640
RE 640
NSC 5844; NSC-5844; RE 640; RE-640; RE640
NSC5844 (RE640)
NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844
140926-75-6