N6-benzoyl-Cyclic AMP (sodium salt)

N6-benzoyl-Cyclic AMP (sodium salt) Struktur
1135306-29-4
CAS-Nr.
1135306-29-4
Englisch Name:
N6-benzoyl-Cyclic AMP (sodium salt)
Synonyma:
N6-benzoyl-Cyclic AMP (sodium salt);6BnzcAMP sodium salt,6 Bnz cAMP sodium salt
CBNumber:
CB63152696
Summenformel:
C17H15N5NaO7P
Molgewicht:
457.31
MOL-Datei:
1135306-29-4.mol

N6-benzoyl-Cyclic AMP (sodium salt) Eigenschaften

storage temp. 
Store at -20°C
Löslichkeit
Soluble in H2O
Aggregatzustand
crystalline solid
Wasserlöslichkeit
Soluble to 100 mM in water

Sicherheit

N6-benzoyl-Cyclic AMP (sodium salt) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

N6-benzoyl-Cyclic AMP (6-Bnz-cAMP) is a cell permeable cAMP analog that selectively activates PKA over exchange proteins activated by cAMP (Epac1 and 2, also known as RAPGEF3 and 4). It binds the AI and AII subunits of PKA with pKi values of 4.0 and 3.8, respectively, whereas it binds Epac1 with a pKi value of 1.3. 6-Bnz-cAMP stimulates the phosphorylation of the PKA substrate CREB but does not activate the Epac target Rap1. It can act synergistically with Epac-selective activators, such as 8-pCPT-2’-O-Me-cAMP .

N6-benzoyl-Cyclic AMP (sodium salt) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N6-benzoyl-Cyclic AMP (sodium salt) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • N6-benzoyl-Cyclic AMP (sodium salt)
  • 6BnzcAMP sodium salt,6 Bnz cAMP sodium salt
  • 1135306-29-4
  • C17H15N5NaO7P
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