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[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride

[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride Struktur
16777-42-7
CAS-Nr.
16777-42-7
Englisch Name:
[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride
Synonyma:
D 563;Modacor;Ildamen;FDA 1576;OXYFEDRINE HCL;L-OXYFEDRINE HCL;Ildamen USP/EP/BP;L-Form hydrochloride;Oxyfedrine L-form HCl;OXYFEDRINEHYROCHLORIDE
CBNumber:
CB7882175
Summenformel:
C19H24ClNO3
Molgewicht:
349.85176
MOL-Datei:
16777-42-7.mol
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[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride Eigenschaften

Schmelzpunkt:
192-194℃

Sicherheit

Toxizität LD50 in mice (mg/kg): 29 i.v. (Hueller)

[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Ildamen,Homburg,W. Germany ,1966

Manufacturing Process

45 grams of m-methoxy acetophenone, 8 grams of paraformaldehyde and 30.2 grams of 1 norephedrine were mixed with about 135 cc of isopropanol HCl solution to provide a pH of 4 and the mixture refluxed for 4 hours. The reaction mixture was cooled and the crystals filtered off on a suction filter. 3[1-phenyl-1-hydroxypropyl-(2)-amino]-1-(m-methoxyphenyl)-propanone-(1) HCl was obtained which after recrystallization from methanol had a MP of 190° to 193°C.

Therapeutic Function

Coronary vasodilator

[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

L-Norephedrin 3-Methoxyacetophenon Paraformaldehyde

Downstream Produkte

[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 31)Lieferanten
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Amadis Chemical Company Limited 		571-89925085
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16777-42-7()Verwandte Suche:

p-Methoxypropiophenon 3-((2-Hydroxy-1-methyl-2-phenyl-ethyl)amino)-1-(3-methoxyphenyl)-1-propanon-hydrochlorid
  • [R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride
  • OXYFEDRINE HCL
  • OXYFEDRINEHYROCHLORIDE
  • L-OXYFEDRINE HCL
  • D 563
  • FDA 1576
  • Ildamen
  • l-Oxyfedrine hydrochloride
  • Modacor
  • L-Form hydrochloride
  • (3R)-3-(((1S)-1-Hydroxy-1-phenylpropan-2-yl)amino)-3-methoxy-1-phenylpropan-1-one hydrochloride
  • 3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)-1-propanone hydrochloride
  • Ildamen USP/EP/BP
  • [R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride USP/EP/BP
  • 3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one,hydrochloride
  • Oxyfedrine L-form HCl
  • Oxyfedrine L-form hydrochloride
  • [R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride
  • 16777-42-7
  • C19H23NO3ClH
  • C19H23NO3HCl
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