DFMO

DFMO Struktur
70052-12-9
CAS-Nr.
70052-12-9
Englisch Name:
DFMO
Synonyma:
DIFLUOROMETHYLORNITHINE;DFMO;RFI 71782;Ccris 3295;Brn 2250529;EFLORNITINE;DL-EFLORNITHINE;H-DL-(F2ME)ORN-OH;α-Difluoromethylornitine;α-difluoromethylornithine
CBNumber:
CB8373227
Summenformel:
C6H12F2N2O2
Molgewicht:
182.17
MOL-Datei:
70052-12-9.mol

DFMO Eigenschaften

Schmelzpunkt:
138 °C
Siedepunkt:
347.0±42.0 °C(Predicted)
Dichte
1.1800 (estimate)
storage temp. 
Store at 0°C
Löslichkeit
H2O: >10 mg/mL, soluble
pka
1.22±0.44(Predicted)
Aggregatzustand
solid
Farbe
white

Sicherheit

WGK Germany  3
Giftige Stoffe Daten 70052-12-9(Hazardous Substances Data)

DFMO Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Off-white powder

Verwenden

DL-α-Difluoromethylornithine hydrochloride hydrate has been used to reduce the effects of arginine on cell proliferation. It has also been used to investigate the effect of bisphenol A (BPA) on the migration of an established ovine trophectoderm (oTr1) cell line.

Allgemeine Beschreibung

Difluoromethylornithine is a?fluorinated ornithine analog, which acts as a rate-limiting enzyme of polyamine biosynthesis. It is used to treat female facial hirsutism and human African trypanosomiasis. Difluoromethylornithine functions as a chemopreventive and chemotherapeutic agent against neuroblastoma and colorectal cancer. It exhibits cytostatic?effects on mammalian cells and tissues.

Biologische Aktivität

Inhibitor of ornithine decarboxylase that inhibits polyamine biosynthesis. Displays antiapoptotic, antiangiogenic and antiparasitic activity.

DFMO Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


DFMO Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 64)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
+16314854226
inquiry@bocsci.com United States 19743 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763
sales@tnjchem.com China 25363 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131981 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2127 70
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
China 1494 55

70052-12-9()Verwandte Suche:


  • 96020-91-6 (Mono-hydrochloride, monohydrate)
  • alpha,delta-Diamino-alpha-(difluoromethyl)valeric acid
  • Brn 2250529
  • Ccris 3295
  • DL-2-(Difluoromethyl)-ornithinehydrochloride
  • DL-α-Difluoromethylornithine hydrochloride hydrate,2-(Difluoromethyl)ornithine hydrochloride hydrate, DFMO hydrochloride hydrate, Eflornithine hydrochloride hydrate
  • DIFLUOROMETHYLORNITHINE(RG)
  • α-Difluoromethyl-DL-ornithine
  • DFMO hydrochloride hydrate
  • DL-α-Difluoromethylornithine hydrochloride hydrate
  • RFI 71782
  • DL-2-(DIFLUORO-METHYL)-ORNITHINE HCL
  • DL-(α-difluoromethyl)Orn-OH
  • α-Difluoromethyl-DL-ornithine≥ 98% (NMR)
  • 2-(difluoromethyl)-ornithin
  • alpha-difluoromethylornithine
  • alpha-difluromethylornithine
  • ALPHA-DIFLUORO-ME-DL-ORNITHINE
  • ALPHA-DIFLUOROMETHYL-DL-ORNITHINE
  • 2-(Difluoromethyl)ornithine hydrate hydrochloride, DFMO hydrate hydrochloride
  • DL-α-Difluoromethylornithine hydrate hydrochloride
  • 2-(Difluoromethyl)-2,5-diaminovaleric acid
  • α-Difluoromethylornitine
  • DL-α-Difluoromethylornithine hydrochloride
  • H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH
  • H-DL-(F2ME)ORN-OH
  • H-ALPHA-DIFLUORO-ME-DL-ORN-OH
  • EFLORNITINE
  • DL-ALPHA-DIFLUOROMETHYLORNITHINE
  • DFMO
  • DL-ALPHA-DIFLUOROMETHYLORNITHINE HYDROCHLORIDE HYDRATE
  • Ornithine, 2-(difluoromethyl)-
  • Eflornithine base (racemic)
  • DL-EFLORNITHINE
  • EflornithineQ: What is Eflornithine Q: What is the CAS Number of Eflornithine Q: What is the storage condition of Eflornithine Q: What are the applications of Eflornithine
  • α-difluoromethylornithine
  • DIFLUOROMETHYLORNITHINE
  • MFCD00221766 Eflornithine
  • 70052-12-9
  • C6H12N2O2F2
  • Angiogenesis Inhibitors
  • Angiogenesis
  • BioChemical
  • Cancer Research
  • facial hair remover
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