ABP688

924298-51-1

CAS-Nr.: 924298-51-1

Englisch Name:: ABP688

Synonyma:: ABP688;ABP 924298-51-1;3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime;3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime;2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime

CBNumber:: CB92669578

Summenformel:: C15H16N2O

Molgewicht:: 240.3

MOL-Datei:: 924298-51-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 16

ABP688 Eigenschaften

Siedepunkt:: 361.4±52.0 °C(Predicted)

Dichte: 1.03±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMSO: 100 mM

Aggregatzustand: A solid

pka: 2.78±0.19(Predicted)

Sicherheit

ABP688 Chemische Eigenschaften,Einsatz,Produktion Methoden

Enzyminhibitor

This high-affinity mGluR antagonist (FW = 240.31 g/mol; CAS 924298- 51-1; Soluble to 100 mM in DMSO; 50 mM in 1 eq. HCl), also named 3- [2-(6-methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime, targets the human metabolotrophic glutamate receptor-5 (mGluR5) (Ki = 1.7 nM) and inhibits glutamate-induced calcium release from Ltk-cells expressing human mGlu5 receptors (IC50 = 2.3 nM). Indeed, [11C]- ABP688 is a useful PET tracer for in vivo imaging of the mGluR5 in rodents.

ABP688 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ABP688 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 16)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3501	55
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	63720	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	market@aladdin-e.com	China	48467	58
United States Biological	--	sales@advtechind.com	United States	6106	58

ABP688
ABP 924298-51-1
3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime
2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime
3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime
924298-51-1