CFI-400945

1338806-73-7

CAS-Nr.: 1338806-73-7

Englisch Name:: CFI-400945

Synonyma:: CFI-400945;ocifisertib;CFI-400945 (CFI400945;CFI-400945 (free base);CFI400945 free base,CFI 400945 free base;(1R,2S)-2-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methoxy-spiro[cyclopropane-1,3'-indoline]-2'-one;(1R,2S)-2-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methoxy-spiro[cyclopropane-1,3'-indoline]-2'-one;Spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one, 2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5'-methoxy-, (1R,2S)-

CBNumber:: CB92716177

Summenformel:: C33H34N4O3

Molgewicht:: 534.65

MOL-Datei:: 1338806-73-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 60

CFI-400945 Eigenschaften

Siedepunkt:: 751.5±60.0 °C(Predicted)

Dichte: 1.32±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: insoluble in H2O; ≥109.8 mg/mL in DMSO; ≥93 mg/mL in EtOH

Aggregatzustand: crystalline solid

pka: 13.09±0.40(Predicted)

Sicherheit

CFI-400945 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(1R,?2S)?-2-?[3-?[(1E)?-?2-?[4-?[[(2R,?6S)?-?2,?6-?Dimethyl-?4-?morpholinyl]?methyl]?phenyl]?ethenyl]?-?1H-?indazol-?6-?yl]?-?5''-?methoxy-?spiro[cyclopropane-?1,?3''-?[3H]?indol]?-?2''(1''H)?-?one selectively inhibits polo-like kinase 4 (PLK4), which is a serine/threonine protein kinase that regulates centriole duplication during the cell cycle. PLK4 is a therapeutic target for various cancers.

CFI-400945 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CFI-400945 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 60)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32715	60
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323967 +86-18015559028	sales1@artkmedchem.com	China	39009	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
Shanghai Jian Chao Chemical Technology Co., Ltd.	18017383231 18017383231	lyh_antaeus@163.com	China	9352	55
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3423	58

CFI-400945
CFI-400945 (free base)
CFI-400945 (CFI400945
Spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one, 2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5'-methoxy-, (1R,2S)-
ocifisertib
CFI400945 free base,CFI 400945 free base
(1R,2S)-2-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methoxy-spiro[cyclopropane-1,3'-indoline]-2'-one
(1R,2S)-2-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methoxy-spiro[cyclopropane-1,3'-indoline]-2'-one
1338806-73-7
338806-73-7
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