HEXOPRENALINE SULPHATE
- CAS No.
- 3215-70-1
- Chemical Name:
- HEXOPRENALINE SULPHATE
- Synonyms
- ST 1512;Ipradol;Byk 1512;Hyssonarin;Hexoprenaline;HEXOPRENALINE SULFATE;HEXOPRENALINE SULPHATE;Hexoprenaline (10mM in DMSO);HEXOPRENALINE SULPHATE USP/EP/BP;N,N'-Bis[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]hexamethylenediamine
- CBNumber:
- CB0144463
- Molecular Formula:
- C22H34N2O10S
- Molecular Weight:
- 518.58
- MDL Number:
- MFCD00867050
- MOL File:
- 3215-70-1.mol
- MSDS File:
- SDS
| Melting point | 162-165° (hemihydrate) |
|---|---|
| storage temp. | Refrigerator |
| solubility | Aqueous Base (Slightly), DMSO (Slightly) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | G9L6B3W684 |
| ATC code | R03AC06,R03CC05 |
HEXOPRENALINE SULPHATE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | H295460 | Hexoprenaline | 3215-70-1 | 2.5mg | $180 | 2021-12-16 | Buy |
| TRC | H295460 | Hexoprenaline | 3215-70-1 | 25mg | $1390 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0011618 | HEXOPRENALINE 95.00% | 3215-70-1 | 10MG | $329.7 | 2021-12-16 | Buy |
HEXOPRENALINE SULPHATE Chemical Properties,Uses,Production
Originator
Etoscol,Byk Gulden,W. Germany,1973
Uses
Hexoprenaline acts as a β2-adrenoreceptor agonist/betamimetic and a vasoactive agent.
Manufacturing Process
The N,N'-dibenzyl-N,N'-bis-[2-(3',4'-dihydroxyphenyl)-2-oxoethyl]-
hexamethylene-diamine dichlorohydrate-monohydrate used as the starting
material was prepared as follows: 2 mols of chloroaceto pyrocatechin were
dissolved in 2,000 cc of acetone and heated to boiling with 2 mols of N,N'-
dibenzylhexamethylene-diamine for 12 hours, almost the theoretical quantity
of N,N'-dibenzylhexamethylene-diamine dichlorohydrate being precipitated and
removed by suction after cooling. Excess HCl was added to the filtrate,
approximately 66% of the theoretically possible quantity of crude
dichlorohydrate of the N,N'-dibenzyl-N,N'-bis-[2-(3',4'-dihydroxyphenyl)-2-oxoethyll-hexamethylene-diamine being precipitated. The product was cleaned
by recrystallization from water with the addition of animal charcoal. After
drying the substance contained water of crystallization at ambient
temperature, MP 206° to 209.5°C.
Five grams of N,N'-dibenzyl-N,N'-bis[2-(3',4'-dihydroxyphenyl)-2-oxoethyl]-
hexamethylenediamine dichlorohydrate as a monohydrate were hydrogenated
under considerable agitation by means of 2.0 grams of 10% palladium-carbon,
with hydrogen in a mixture of 270 cc of methanol and 50 cc of water at 45°C
and normal pressure. After about 4 hours the theoretical quantity of hydrogen
(4 mols of hydrogen per 1 mol of substance) was absorbed for the splitting off
of the two benzyl radicals and the reduction of the two carbonyl groups to
carbinol groups, and the hydrogenation came to a stop.
After separation of the catalyst the product was concentrated until dry, the
residue was triturated with acetone, the resulting crystallizate was removed
by suction and washed with acetone. The yield of N,N'-bis-2-(3',4'-
dihydroxyphenyl)-2-hydroxyethyll-hexamethylene-diamine dichlorohydrate was
3.3 grams, i.e., 92% of the theoretical value. A quantity of 2.8 grams having
a melting point of 197.5° to 198°C was obtained by precipitation from a
mixture of methanol-ether.
Free N,N'-bis-[2-(3',4'-dihydroxyphenyl)-2-hydroxyethyl]-hexamethylenediamine can be separated from these salts by the addition of the equivalent
quantity of caustic alkali solution. It has a melting point of 162° to 165°C and
contains half a mol of water of crystallization.
N,N'-bis-[2-(3',4'-dihydroxyphenyl)-2-hydroxyethyl]-hexamethylenediaminesulfate (MP 222° to 228°C) can be obtained by reacting the base with
the equivalent quantity of sulfuric acid in an alcohol solution, followed by
concentration and precipitation from water-alcohol solution.
brand name
Delaprem (Savage).
Therapeutic Function
Bronchodilator
HEXOPRENALINE SULPHATE Preparation Products And Raw materials
HEXOPRENALINE SULPHATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3218 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29016 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55827 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
View Lastest Price from HEXOPRENALINE SULPHATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | Ipradol
3215-70-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-05-29 | HEXOPRENALINE SULPHATE USP/EP/BP
3215-70-1
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-04-25 | Hexoprenaline
3215-70-1
|
US $0.01-1.00 / KG | 1KG | 99% | 50 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Ipradol
3215-70-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- HEXOPRENALINE SULPHATE USP/EP/BP
3215-70-1
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Hexoprenaline
3215-70-1
- US $0.01-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd