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11(12)-EpETE

CAS No.
504435-15-8
Chemical Name:
11(12)-EpETE
Synonyms
11(12)-EpETE;11(12)-EpETE Exclusive;11,12-epoxy-5(Z),8(Z),14(Z),17(Z)- eicosatetraenoic acid;5,8-Decadienoic acid, 10-[3-(2Z,5Z)-2,5-octadien-1-yl-2-oxiranyl]-, (5Z,8Z)-
CBNumber:
CB02589840
Molecular Formula:
C20H30O3
Molecular Weight:
318.45
MDL Number:
MOL File:
504435-15-8.mol
Last updated:2023-05-21 10:59:17

11(12)-EpETE Properties

storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

11(12)-EpETE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10462 (±)11(12)-EpETE ≥98% 504435-15-8 25μg $48 2024-03-01 Buy
Cayman Chemical 10462 (±)11(12)-EpETE ≥98% 504435-15-8 50μg $89 2024-03-01 Buy
Cayman Chemical 10462 (±)11(12)-EpETE ≥98% 504435-15-8 100μg $168 2024-03-01 Buy
Cayman Chemical 10462 (±)11(12)-EpETE ≥98% 504435-15-8 500μg $739 2024-03-01 Buy
American Custom Chemicals Corporation LIP0000621 (+/-)11(12)-EPOXY-5Z,8Z,14Z,17Z- EICOSATETRAENOIC ACID 95.00% 504435-15-8 5MG $505.47 2021-12-16 Buy
Product number Packaging Price Buy
10462 25μg $48 Buy
10462 50μg $89 Buy
10462 100μg $168 Buy
10462 500μg $739 Buy
LIP0000621 5MG $505.47 Buy

11(12)-EpETE Chemical Properties,Uses,Production

Uses

Eicosapentaenoic acid (EPA; ) is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by binding large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)11(12)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.[Cayman Chemical]

Definition

ChEBI: (5Z,8Z,14Z,17Z)-11,12-epoxyicosatetraenoic acid is an EpETE obtained by formal epoxidation of the 11,12-double bond of all-cis-5,8,11,14,17-icosapentaenoic acid. It is functionally related to an all-cis-5,8,11,14,17-icosapentaenoic acid. It is a conjugate acid of a (5Z,8Z,14Z,17Z)-11,12-epoxyicosatetraenoate.

11(12)-EpETE Preparation Products And Raw materials

Raw materials

Preparation Products

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Alfa Chemistry
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Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
11(12)-EpETE 11,12-epoxy-5(Z),8(Z),14(Z),17(Z)- eicosatetraenoic acid 5,8-Decadienoic acid, 10-[3-(2Z,5Z)-2,5-octadien-1-yl-2-oxiranyl]-, (5Z,8Z)- 11(12)-EpETE Exclusive 504435-15-8