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BAFILOMYCIN C1

CAS No.
88979-61-7
Chemical Name:
BAFILOMYCIN C1
Synonyms
L-681110A1;BAFILOMYCIN C1;Antibiotic L-681110A1;Bafilomycin C-1,Bafilomycin C1;2-Demethyl-2-methoxy-24-methylhygrolidin;Bafilomycin C1, from Streptomyces griseus;2-Butenedioic acid (2E)-, 1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester
CBNumber:
CB0320023
Molecular Formula:
C39H60O12
Molecular Weight:
720.89
MDL Number:
MFCD00904461
MOL File:
88979-61-7.mol
Last updated:2023-06-30 15:45:59

BAFILOMYCIN C1 Properties

storage temp. Store at -20°C
solubility DMSO: 5 mg/ml; Methanol: 5 mg/ml
form White to light-brown solid.
color Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
NFPA 704
0
4 0

BAFILOMYCIN C1 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19625 Bafilomycin C1 ≥95% 88979-61-7 1mg $81 2024-03-01 Buy
Cayman Chemical 19625 Bafilomycin C1 ≥95% 88979-61-7 5mg $383 2024-03-01 Buy
Usbiological 207085 Bafilomycin C1 88979-61-7 1mg $402 2021-12-16 Buy
Usbiological B0003-72 Bafilomycin C1 88979-61-7 1mg $426 2021-12-16 Buy
TRC B110003 BafilomycinC1 88979-61-7 0.5mg $435 2021-12-16 Buy
Product number Packaging Price Buy
19625 1mg $81 Buy
19625 5mg $383 Buy
207085 1mg $402 Buy
B0003-72 1mg $426 Buy
B110003 0.5mg $435 Buy

BAFILOMYCIN C1 Chemical Properties,Uses,Production

Uses

Bafilomycin C1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases). It blocks these pumps in mammalian, plant, or fungal cells, preventing proton transport and compartment acidification. Bafilomycin C1 has been shown to have angiostatic activity in the chick chorioallantoic membrane assay. It has also been used, when coupled to cellulose, to purify V-ATPases.[Cayman Chemical]

Uses

Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 shares a similar mode of action and activity as its more accessible A1 analogue. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.

storage

+4°C

BAFILOMYCIN C1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
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BOC Sciences
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Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55827 58
Hefei fuya biotechnology co. LTD 18096409024 sales02@foreversyn.com China 1941 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
2-Demethyl-2-methoxy-24-methylhygrolidin Antibiotic L-681110A1 L-681110A1 BAFILOMYCIN C1 Bafilomycin C1, from Streptomyces griseus 2-Butenedioic acid (2E)-, 1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester Bafilomycin C-1,Bafilomycin C1 88979-61-7 C39H60O12