ChemicalBook >> CAS DataBase List >>N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
- CAS No.
- 88519-57-7
- Chemical Name:
- N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
- Synonyms
- W-13;W-13 HYDROCHLORIDE;OMEGA-13 HYDROCHLORIDE;W-13 HYDROCHLORIDE CALMODULIN ANTAGONIST;N-(4-AMINOBUTYL)-5-CHLORO-2- &;N-(4-aminobutyl)-5-chloro-2-*naphthalenesulfonami;W-13, Hydrochloride - CAS 88519-57-7 - Calbiochem;N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HCL;4-[(5-chloro-2-naphthalenyl)sulfonylamino]butylammonium;N-(4-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride
- CBNumber:
- CB0466031
- Molecular Formula:
- C14H18Cl2N2O2S
- Molecular Weight:
- 349.28
- MDL Number:
- MFCD00058030
- MOL File:
- 88519-57-7.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
| Melting point | 241-243°C |
|---|---|
| storage temp. | room temp |
| solubility | H2O: Stock solutions of 5 mM are recommended. These stocks should be stable for up to 6 months when stored at 4°C.soluble |
| form | powder |
| color | white |
| CAS DataBase Reference | 88519-57-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2935.90.9500 | |||||||||
| NFPA 704 |
|
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0717 | W-13 ≥98% (HPLC) | 88519-57-7 | 5mg | $93.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 681636-M | W-13, Hydrochloride | 88519-57-7 | 1mg-m | $114 | 2021-12-16 | Buy |
| Sigma-Aldrich | 681636-M | W-13, Hydrochloride - CAS 88519-57-7 - Calbiochem A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC?? = 58 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC?? = 68 μM). | 88519-57-7 | 1mg | $114 | 2021-12-16 | Buy |
| TCI Chemical | A2416 | N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride >98.0%(HPLC)(N) | 88519-57-7 | 25mg | $48 | 2023-06-20 | Buy |
| TCI Chemical | A2416 | N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride >98.0%(HPLC)(N) | 88519-57-7 | 500mg | $379 | 2024-03-01 | Buy |
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Chemical Properties,Uses,Production
Description
W-
Chemical Properties
Beige Solid
Uses
Calmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin- regulated activities, including phosphodiesterase activation and myosin light chain kinase127, it is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
Uses
W-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmodulin (IC50 = 22 μM) and is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
Definition
ChEBI: N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide hydrochloride is a hydrochloride salt prepared from equimolar amounts of N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide and hydrogen chloride. It contains a N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide(1+).
Biological Activity
Calmodulin antagonist (inhibits calmodulin activated PDE activity with an IC 50 of 68 μ M). Inhibits growth of tamoxifen-resistant breast cancer cells.
Biochem/physiol Actions
W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells.
storage
Store at RT
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 82)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 | market03@meryer.com | China | 40241 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
View Lastest Price from N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
88519-57-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
88519-57-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
88519-57-7(N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE)Related Search:
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N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENE SULPHONAMIDE, HYDROCHLORIDE
OMEGA-13 HYDROCHLORIDE
W-13
W-13 HYDROCHLORIDE
N-(4-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride
(+)-5-Hydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
N-(4-Aminobutyl)-5-chloronaphthalene-2-sulphonamide hydrochloride
N-(4-aminobutyl)-5-chloro-2-*naphthalenesulfonami
N-(4-AMINOBUTYL)-5-CHLORO-2- &
W-13 HYDROCHLORIDE CALMODULIN ANTAGONIST
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HCL
N-(4-AMinobutyl)-5-chloro-2-naphthalenesulfonaMide Monohydrochloride
2-NaphthalenesulfonaMide, N-(4-aMinobutyl)-5-chloro-, Monohydrochloride
N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride
N-(4-AMinobutyl)-5-chloronaphthalene-2-sulfonaMide Hydrochloride
W-13, Hydrochloride - CAS 88519-57-7 - Calbiochem
4-[(5-chloro-2-naphthalenyl)sulfonylamino]butylammonium
N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride >
88519-57-7
C14H18Cl2N2O2S
C14H17ClN2O2SHCl
Intracellular Calcium Signaling
Cell Biology
Calcium Antagonists
Cell Signaling and Neuroscience
BioChemical
All Inhibitors
Inhibitors
Protein Kinase Inhibitors and Activators
Calcium signaling
Amines
Aromatics
Sulfur & Selenium Compounds