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4-(3'-Methylphenyl)amino-3-pyridinesulfonamide

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide Structure
4-(3'-Methylphenyl)amino-3-pyridinesulfonamide structure
CAS No.
72811-73-5
Chemical Name:
4-(3'-Methylphenyl)amino-3-pyridinesulfonamide
Synonyms
BM 960102;Torsemide Imp B;TORSEMIDE EP IMP B;4-(3'-Methylphenyl)a;TorseMide IMpurity B;SPECS AJ-333/25006115;Torasemide intermediate;Torsemide EP Impurity B;Torasemide EP Impurity B;Torasemide impurity B (EP)
CBNumber:
CB0486466
Molecular Formula:
C12H13N3O2S
Molecular Weight:
263.32
MDL Number:
MFCD00661332
MOL File:
72811-73-5.mol
Last updated:2024-04-07 09:05:03
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4-(3'-Methylphenyl)amino-3-pyridinesulfonamide Properties

Melting point 162-164?C
Boiling point 475.8±55.0 °C(Predicted)
Density 1.357±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.53±0.60(Predicted)
color White to Off-White
BRN 5438165
InChIKey ZXPCUGWAKUIOOF-UHFFFAOYSA-N
CAS DataBase Reference 72811-73-5(CAS DataBase Reference)
FDA UNII 7GN70NEN27

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
HS Code  2935909550

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1672315 Torsemide Related Compound A United States Pharmacopeia (USP) Reference Standard 72811-73-5 75mg $1630 2024-03-01 Buy
Sigma-Aldrich PHR3145 Torsemide Related Compound A pharmaceutical secondary standard, certified reference material 72811-73-5 150MG $466 2022-05-15 Buy
TCI Chemical T3007 4-(m-Tolylamino)pyridine-3-sulfonamide >98.0%(HPLC)(T) 72811-73-5 5g $169 2024-03-01 Buy
TCI Chemical T3007 4-(m-Tolylamino)pyridine-3-sulfonamide >98.0%(HPLC)(T) 72811-73-5 25g $834 2021-12-16 Buy
TRC M320675 4-[(3-Methylphenyl)amino]-3-pyridinesulfonamide 72811-73-5 5g $300 2021-12-16 Buy
Product number Packaging Price Buy
1672315 75mg $1630 Buy
PHR3145 150MG $466 Buy
T3007 5g $169 Buy
T3007 25g $834 Buy
M320675 5g $300 Buy

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

Torasemide intermediate.

Synthesis

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide is prepared by the reaction of 4-Chloropyridine-3-sulfonamide hydrochloride and 3-Methylaniline. The specific synthesis steps are as follows:
EXAMPLE 1; Preparation of 4-(3-methylphenyl)aminopyridine-sulfonamide; 2L three-neck flask, equipped with a mechanical stirrer, thermometer and condenser, was charged with water (500 ml) and 4-chloro-3- pyridinesulfonamide hydrochloride (100g, 0.44 mol). To this suspension was added m-toluidine (49.2 ml, 0.46 mol) at room temperature. The reaction mixture was heated to 90°C for a minimum period of 3 h. The progress of the reaction was followed by HPLC. After completion, the mixture was cooled to room temperature. The pH of the reaction was then adjusted carefully to pH 7-8 with sat. NaHC03 (ca. 1.1 l). The product was precipitated out and isolated by vacuum filtration as beige solid (126.2 g wet weight). The product was then dissolved in MeOH (1.0 l) at room temperature and charged with Darco KB (25g). The solution was refluxed for 0.5 h and then filtered through a patch of celite to remove Darco KB, while still hot, and rinsed with hot MeOH (200 ML). The filtrate was then charged with water (1.2 l) and stirred for a minimum of 1 h at room temperature. The product, which had precipitated out, was isolated by vacuum filtration to obtain a solid 106.3 g (92percent wet weight =>99.8percent purity a/a). 1H NMR (d6-DMSO) ; 2.30 (s, 3H), 7.00-7. 15 (m. 5H), 7.32 (m, 1H), 7.75 (brs, 1.5H), 8.05 (brs, 0.5H), 8.25 (d, 1H), 8.68 (s, 1H).
4-(3'-Methylphenyl)amino-3-pyridinesulfonamide synthesis

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide synthesis

777854-85-0
108-44-1
72811-73-5
Synthesis of 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide from 4-Chloro-3-pyridinesulfonamide hydrochloride,98% and m-Toluidine

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide Preparation Products And Raw materials

Raw materials

4-Amino-3-pyridinesulfonamide 4-Chloro-3-pyridinesulfonamide hydrochloride,98% 4-Chloro-3-pyridinesulfonamide 3-Iodotoluene m-Toluidine

Preparation Products

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide Suppliers

Global( 312)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Xiamen AmoyChem Co., Ltd 		+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Xiamen AmoyChem Co., Ltd 		58
Standardpharm Co. Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
SIMAGCHEM CORP 		58

View Lastest Price from 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(3'-Methylphenyl)amino-3-pyridinesulfonamide pictures 2024-04-17 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide
72811-73-5
 US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
4-(3'-Methylphenyl)amino-3-pyridinesulfonamide pictures 2023-03-11 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide
72811-73-5
 US $45.00 / kg 1kg 99% 5000 tons Hebei Duling International Trade Co. LTD
4-(3'-Methylphenyl)amino-3-pyridinesulfonamide pictures 2021-11-19 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide
72811-73-5
 US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd

72811-73-5(4-(3'-Methylphenyl)amino-3-pyridinesulfonamide)Related Search:

Torasemide Impurity 4-CHLORO-3-PYRIDINESULFONIC ACID 2-Pyridinesulfonamide,4-chloro-(9CI) 4-Hydroxypyridine-3-sulfonic acid 4-Chloro-3-Pyridine-sulfonyl-chloride
Torsemide Related Compound 1 [[4-[(3-Methylphenyl)aMino]-3-pyridinyl]sulfonyl]carbaMic Acid Ethyl Ester Torsemide Impurity E 1-Ethyl-3-[[4-(m-toluidino)-3-pyridyl]sulfonyl]urea N-[(n-butylaMino)carbonyl]-4-[(3-Methylphenyl)aMino]-3-pyridinesulfonaMide
Torasemide 4-(3-Methylphenyl)-2H-pyrido[4,3-e]-1,2,4-thiadiazin-3(4H)-one 1,1-Dioxide N-[[(1-Methylethyl-d7)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide 3-Pyridinesulfonamide Sulfamide
4-(3'-Methylphenyl)amino-3-pyridinesulfonamide Galosemide TORSEMIDE RELATED COMPOUND A (75 MG) (4-[(3-METHYLPHENYL)AMINO]-3-PYRIDINESULFONAMIDE)

1of4

4-(-3-METHYLPHENYL)AMINO-3-PYRIDINESULFONAMIDE 4-(3'-METHYLPHENYL)AMINO-3-PYRIDINESULFONAMIDE 3-SULFONAMIDO-4-(3-METHYLANILINO)-PYRIDINE SPECS AJ-333/25006115 4-(3-METHYLPHENYL)AMINO-3-PYRIDINESULFONAMIDE (SMPAP) 4-[3-Methyl phenyl] amino-3-pyridine sulphonamide Torasemide intermediate [4-(3-Methylphenyl)amino]pyrid 4-(3-methylphenyl)amino-3-pyridine sulfonamide (intermediate of torasemide) 4-(3-methylphenylamino) Pyridine-3-sulfonamide [4-3-Methylphenyl)amino]pyridine-3-sulphonamide 4-(3-METHYLPHENYL)AMINO-3-PYRIDINESULFONAMIDE 98% 4-(3'-Methylphenyl)a TorseMide Related CoMpound A BM 960102 4-(M-TolylaMino)pyridine-3-sulfonaMide TorseMide IMpurity B Standard for Torasemide Impurity Torasemide Impurity 2（Torasemide EP Impurity B） Torasemide EP Impurity B Torasemide impurity B (EP) 4-[(3-Methylphenyl)amino]-pyridin-3-sulfonamide Torsemide USP Related Compound A Torasemi Impurity B Standard 4[(3-Methyl Phenyl) amino] 3-Pyridine Sulfonamide (Torsamide Intermediate) (72811-73-5) 4-[(3-Methylphenyl)amino]pyridine-3 3-Pyridinesulfonamide, 4-[(3-methylphenyl)amino]- Torsemide EP Impurity B 4-(3-Methylphenyl)amino-3-sulfamoylpyridine 4-(m-Tolylamino)-3-sulfamoylpyridine 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide ISO 9001：2015 REACH Torsemide EP Impurity B/ Torsemide Related Compound A TIANFU-CHEM_high purity of 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide Torsemide Impurity BQ: What is Torsemide Impurity B Q: What is the CAS Number of Torsemide Impurity B Q: What is the storage condition of Torsemide Impurity B Q: What are the applications of Torsemide Impurity B 4-(3-methylanilinopyridine)-3-sulfonamide Torasemide, Anhydrous Impurity B Torasemide, Anhydrous EP Impurity B 4-(3-Methylphenyl)Amino-3-Pyridinesulfonamide (Torsemide Intermediate) Torsemide Imp B 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide TORSEMIDE EP IMP B 72811-73-5 C12H13N3O2S Aromatics Intermediates & Fine Chemicals Pharmaceuticals INTERMEDIATESOFTORASEMIDE Pyridines derivates (intermediate of torasemide) Pyridines Torsemide 72811-73-5