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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate structure

CAS No.: 184177-81-9

Chemical Name:: Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

Synonyms: Posaconazole SM2;Posaconazole Impurity 14;Posaconazole Impurity 56;Intermediate of Posaconazole;Phenyl (4-(4-(4-hydroxyphenyl);piperazin-1-yl)phenylcarbamate;Posaconazole Hydroxy Carbamate Impurity;Posaconazole Diastereoisomer 3 (S,R,R,R);4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE;PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE

CBNumber:: CB11476162

Molecular Formula:: C23H23N3O3

Molecular Weight:: 389.45

MDL Number:: MFCD03784249

MOL File:: 184177-81-9.mol

MSDS File:: SDS

Last updated:2024-04-22 13:28:05

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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Properties

Boiling point	603.9±55.0 °C(Predicted)
Density	1.296
storage temp.	Sealed in dry,Room Temperature
pka	12.18±0.30(Predicted)
InChI	InChI=1S/C23H23N3O3/c27-21-12-10-20(11-13-21)26-16-14-25(15-17-26)19-8-6-18(7-9-19)24-23(28)29-22-4-2-1-3-5-22/h1-13,27H,14-17H2,(H,24,28)
InChIKey	IKRKMYDCUZYKHX-UHFFFAOYSA-N
SMILES	C(OC1=CC=CC=C1)(=O)NC1=CC=C(N2CCN(C3=CC=C(O)C=C3)CC2)C=C1
CAS DataBase Reference	184177-81-9

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H410
Precautionary statements	P273-P391-P501

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	H950215	[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamicAcidPhenylEster	184177-81-9	1g	$635	2021-12-16	Buy
Matrix Scientific	090772	Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate 95+%	184177-81-9	1g	$1143	2021-12-16	Buy
AK Scientific	W3988	Phenyl(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate	184177-81-9	1g	$70	2021-12-16	Buy
AK Scientific	W3988	Phenyl(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate	184177-81-9	25g	$163	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0393749	PHENYL-(4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL)CARBAMATE 95.00%	184177-81-9	5MG	$498.82	2021-12-16	Buy

Product number	Packaging	Price	Buy
H950215	1g	$635	Buy
090772	1g	$1143	Buy
W3988	1g	$70	Buy
W3988	25g	$163	Buy
CHM0393749	5MG	$498.82	Buy

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Chemical Properties,Uses,Production

Description

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a piperazine derivative that inhibits the growth of gram-positive bacteria.Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)) carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Human activity on human erythrocytes using the membrane clamp technique is frequent. This active form is metabolised by a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or binding to glucuronic acid.

Uses

[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic Acid Phenyl Ester is an impurity of Posaconazole (P689600), which is orally active antifungal triazole.

Uses

PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE is a carboxylic acid ester organic substance and can be used as a pharmaceutical intermediate.

Definition

ChEBI: N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester is a member of piperazines.

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate synthesis

Synthesis of Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate from Phenyl chloroformate and 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Preparation Products And Raw materials

Raw materials

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Phenyl chloroformate

Preparation Products

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Suppliers

Global( 195)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi LuyuanBiomedicine Co., LTD	+86-13991827389 +86-13991827389	sxlysw@sxlysw.com.cn	China	50	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
weifang runzhong fine chemical co., ltd	536-7868377 +8618653686003	sq@runzhongchem.com	China	187	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Shaanxi LuyuanBiomedicine Co., LTD	58
CONIER CHEM AND PHARMA LIMITED	58
weifang runzhong fine chemical co., ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-28	PHENYL (4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL)CARBAMATE 184177-81-9	US $0.00 / kg	25kg	98%	Inquiry	PNP Biotech Co. Ltd
2023-11-01	[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester 184177-81-9	US $0.00-0.00 / kg	1kg	99%min	100kg ; 500kg	Hangzhou ICH Biofarm Co., Ltd
2023-11-01	(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 184177-81-9	US $0.00-0.00 / kg	1kg	99%min	100kg ; 500kg	Hangzhou ICH Biofarm Co., Ltd

PHENYL (4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL)CARBAMATE
184177-81-9
US $0.00 / kg
98%
PNP Biotech Co. Ltd

[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester
184177-81-9
US $0.00-0.00 / kg
99%min
Hangzhou ICH Biofarm Co., Ltd

(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
184177-81-9
US $0.00-0.00 / kg
99%min
Hangzhou ICH Biofarm Co., Ltd

184177-81-9(Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate)Related Search:

4-Methoxyphenol Posaconazole Impurity 44 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Posaconazole Impurity 51 D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-

4-([4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-CARBAMIC ACID PHENYL ESTER 1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine Posaconazole Impurity 47 Posaconazole Impurity 42 1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole

1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- 1-(4-Methoxyphenyl)piperazine Posaconazole Impurity 50 Hydrazine, [1-ethyl-2-(phenylmethoxy)propyl]-,[S-(R*,R*)]-(9CI) [(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazine

2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine 4-Chloro-benzenesulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl ester

1of4

CarbaMic acid, [4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester (9CI) Posaconazole Impurity 14 PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester Phenyl (4-(4-(4-hydroxyphenyl) phenyl N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]carbamate 4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE Phenyl {4-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Phenyl}Carbamat... Posaconazole SM2 Carbamic acid, N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester Posaconazole Hydroxy Carbamate Impurity Posaconazole Impurity 56 piperazin-1-yl)phenylcarbamate Posaconazole Diastereoisomer 3 (S,R,R,R) Intermediate of Posaconazole Phenyl {4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl}carbamate 184177-81-9