ChemicalBook >> CAS DataBase List >>2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, structure

CAS No.: 184177-83-1

Chemical Name:: 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

Synonyms: ChemicalBook;2-((2S,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one;1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one;2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one;BSKZ-2;Posaconazole B;4-Triazol-3-one;Posaconazole POB;Posaconazole int2

CBNumber:: CB11553210

Molecular Formula:: C30H35N5O3

Molecular Weight:: 513.63

MDL Number:: MFCD18374617

MOL File:: 184177-83-1.mol

MSDS File:: SDS

Last updated:2023-04-27 16:27:43

Request For Quotation

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, Properties

Melting point	195-197oC
Boiling point	685.4±65.0 °C(Predicted)
Density	1.22
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	12.18±0.30(Predicted)
form	Solid
color	White
CAS DataBase Reference	184177-83-1(CAS DataBase Reference)
FDA UNII	AH978V32DS

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	E925535	2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one	184177-83-1	1g	$1040	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0068924	2-[(1S,2S)-1-ETHYL-2-BENZYLOXYPROPYL]-2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE 95.00%	184177-83-1	10MG	$1963.5	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0068924	2-[(1S,2S)-1-ETHYL-2-BENZYLOXYPROPYL]-2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE 95.00%	184177-83-1	1MG	$750.75	2021-12-16	Buy
Matrix Scientific	089902	1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)-piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 95+%	184177-83-1	5g	$788	2021-12-16	Buy
Ark Pharm	AK-89728	1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 98+%	184177-83-1	1g	$43	2021-12-16	Buy

Product number	Packaging	Price	Buy
E925535	1g	$1040	Buy
CHM0068924	10MG	$1963.5	Buy
CHM0068924	1MG	$750.75	Buy
089902	5g	$788	Buy
AK-89728	1g	$43	Buy

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, Chemical Properties,Uses,Production

Chemical Properties

Grey Solid

Uses

Intermediate in the preparation of Posaconazole (P689600).

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, synthesis

Synthesis of 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, from Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate and 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, Preparation Products And Raw materials

Raw materials

Preparation Products

O-Benzyl Posaconazole

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, Suppliers

Global( 321)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd	+86-010-83386758 +86-18810831598	jennifer@lianben.com	China	85	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	925	58
Hangzhou Cyanochem Co., Ltd.	+86 17788583750	sales@cyanochem.com	CHINA	283	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58
Hangzhou Cyanochem Co., Ltd.	58

View Lastest Price from 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-11-24	Posaconazole intermediate 184177-83-1	US $0.00-0.00 / g	1g	≥99%	1-10000g	Changzhou Rokechem Technology Co., Ltd.
2022-09-30	2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]... 184177-83-1	US $0.00-0.00 / KG	1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.
2022-09-21	Posaconazole synthetic intermediate 184177-83-1	US $200.00-182.00 / KG	1KG	99%	9000kg/per week	Hebei Lingding Biotechnology Co., Ltd.

Posaconazole intermediate
184177-83-1
US $0.00-0.00 / g
≥99%
Changzhou Rokechem Technology Co., Ltd.

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]...
184177-83-1
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

Posaconazole synthetic intermediate
184177-83-1
US $200.00-182.00 / KG
99%
Hebei Lingding Biotechnology Co., Ltd.

184177-83-1(2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,)Related Search:

Lercanidipine Butenafine hydrochloride Posaconazole (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Trimethoxyphenylsilane

3-Chloropropyltrimethoxysilane 3-Aminopropyltriethoxysilane Ethanol Ethyl formate Ethyl acetate

Ethyl acrylate ISOXADIFEN-ETHYL Ethyl pyruvate N,N-Diisopropylethylamine N-Aminoethylpiperazine

Ethylparaben Posaconazole Impurity 44 1-(4-Methoxyphenyl)piperazine

1of4

2-[(1S,2S)-2-benzyloxy-1-ethyl-propyl]-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Posaconazole int2 Posaconazole Intermediate2 1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)-piperazin-1-yl)phenyl)-1H-1,2,4 Posa-O 1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 2-(2(S)-Benzyloxy-1(S)-ethyl-propyl)-4-{4-[4-(4-hydroxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]triazol-3-one 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one Posaconazole side chain [S-(R*,R*)]-2-[1-Ethyl-2-(phenylMethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, 2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]- 3H-1,2,4-triazol-3-one 2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2H-1,2,4-triazol-3(4H)-one 1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)-piperazin-1-yl)phenyl)-1H-1,2,4-tr 2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4- 2-((1S,2S)-1-ethyl-2-benzyloxyl-propyl-1-yl)-2,4-diH-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-3H-1,2,4-triazol-3-one 3H-1,2,4-Triazol-3-one, 2-[(1S,2S)-1-ethyl-2-(phenylMethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 2-(2(S)-Bezyloxy-1(S)-ethyl-propyl)-4-{4-[4-(4-hydroxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]triazol-3-one Posaconazole inter-2 3H-1,2,4-Triazol-3-one,2-[(1S,2S)-1-ethyl-2-(phenylMethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- US-DMF No.: 033194 2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-... Posaconazole POB Posaconazole Impurity 92 2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperozinyl]phenyl]-3H-1,2,4-triazol-3-one BSKZ-2 POSACONAZOLE CAS 171228-49-2 INTERMEDIATES 2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2H-1,2,4-triazol-3(4H)-one (Posaconazole intermediate) 2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl] Posaconazole Hydroxy O-Benzyl Impurity 2-[(1S,2S)-2-benzyloxy-1-ethyl-propyl]-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol Posazonazole intermediate POB 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-[(2S,3S)-2-phenylmethoxypentan-3-yl]-1,2,4-triazol-3-one Posaconazole Process Related Impurity Posacozole Diastereoisomer Related Compound 6 Posaconazole Impurity 87 Posaconazole Diastereoisomer Related Compound 7 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-oneChemicalBook 4-Triazol-3-one 4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1 2S)-1-ethyl-2-bezyloxypropyl]-2 Posaconazole Diastereoisomer Related Compound 6 ChemicalBook 1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one 2-((2S,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one Posaconazole synthetic intermediate Posaconazole Intermediate 3 :2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-Chemicalbook(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-Triazol-3-one Side chain of Posaconazole side chain of Posaconazole Posaconazole B Best price and High purity supply of Posaconazole Intermediate (cas 184177-83-1) (S),(S)2-(2-benzyloxy-1-ethyl propyl)-4-{4-[4–(4 hydroxy-phenyl)-piperzine-1-yl]-phenyl}-2,4-dihydro-[1,2,4]triazole 3 one Posaconazole Intermediate-B 184177-83-1 149809-43-3 184177-93-1 C30H35N5O3 Posaconazole