ChemicalBook >> CAS DataBase List >>RETRORSINE
RETRORSINE
- CAS No.
- 480-54-6
- Chemical Name:
- RETRORSINE
- Synonyms
- RETRORSIN;Retrosine;RETRORSINE;Retrorcine;β-Longilobine;RETRORSINE(AS);BETA-LONGILOBINE;cis-retronecicacidesterofretronecine;16-dione,12,18-dihydroxy-senecionan-1;12,18-DIHYDROXYSENECIONAN-11,16-DIONE
- CBNumber:
- CB1256406
- Molecular Formula:
- C18H25NO6
- Molecular Weight:
- 351.39
- MDL Number:
- MFCD00870195
- MOL File:
- 480-54-6.mol
Last updated:2023-05-15 10:43:14
| Melting point | 208-211 °C (lit.) |
|---|---|
| alpha | D18 -17.6° (c = 1.99 in ethanol) |
| Boiling point | 485.2°C (rough estimate) |
| Density | 1.32±0.1 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5100 (estimate) |
| storage temp. | 2-8°C |
| pka | 12.00±0.40(Predicted) |
| Merck | 13,8253 |
| InChIKey | BCJMNZRQJAVDLD-VMOBWIEOSA-N |
| CAS DataBase Reference | 480-54-6 |
| EWG's Food Scores | 1 |
| FDA UNII | XJ86XWL8IY |
| IARC | 3 (Vol. 10, Sup 7) 1987 |
| EPA Substance Registry System | Retrorsine (480-54-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300+H310+H330 |
| Precautionary statements | P260-P262-P264-P280-P302+P352+P310-P304+P340+P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 22-36/37/39-45 |
| RIDADR | 1544 |
| WGK Germany | 3 |
| RTECS | VH7525000 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
RETRORSINE price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R0382 | Retrorsine ≥90% (HPLC) | 480-54-6 | 100mg | $261 | 2024-03-01 | Buy |
| Sigma-Aldrich | R0382 | Retrorsine ≥90% (HPLC) | 480-54-6 | 500mg | $898 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL89775 | Retrorsine phyproof Reference Substance | 480-54-6 | 10mg | $342 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0009902 | RETRORSINE 95.00% | 480-54-6 | 10MG | $573.3 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 48570 | Retrorsine | 480-54-6 | 10mg | $585 | 2021-12-16 | Buy |
RETRORSINE Chemical Properties,Uses,Production
Uses
Retrorsine-D4 is a labelled analogue of Retrorsine (R279000). Retrorsine is a pyrrolizidine alkaloid that blocks the hepatocyte cell cycle, ultimately affecting hepatocyte proliferative capacity.
Definition
ChEBI: Retrorsine is a macrolide.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Safety Profile
Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. hhtation data reported. When heated to decomposition it emits toxic fumes of NOx.
Synthesis of RETRORSINE from PUTRESCINE-1,4-14C DIHYDROCHLORIDE and Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-
RETRORSINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 87)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9116 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
480-54-6(RETRORSINE)Related Search:
ALLYL ISOVALERATE
3-METHOXYPYRROLIDINE
(2-Propenyloxy)propanol
Butyl hydroxyacetate
3-ALLYLOXY-1,2-PROPANEDIOL
2-Dimethylaminoethyl acetate
DIMETHYL 2-METHYLADIPATE
3-Butoxypropanamine
2-HYDROXY-3-METHYLBUTYRIC ACID
3-Pyrrolidinol
1of4
BETA-LONGILOBINE
12,18-DIHYDROXYSENECIONAN-11,16-DIONE
RETRORSINE
16-dione,12,18-dihydroxy-senecionan-1
5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-hydroxymethyl-5-3-ethylidene-4
cis-retronecicacidesterofretronecine
methyl(1,6)dioxacyclododeca(2,3,4-gh)pyrrolizidine-2,7-dione
trans-15-ethylidene-12beta-hydroxy-12alpha-hydroxymethyl-13beta-methylsenec-1-
RETRORSINE(AS)
β-Longilobine, 12,18-Dihydroxysenecionan-11,16-dione
β-Longilobine
Retrorcine
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, (3Z,5R,6S,14aR,14bR)-
RETRORSIN
Retrosine
480-54-6
C18H23O5N