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METHOXAMINE HYDROCHLORIDE

METHOXAMINE HYDROCHLORIDE Structure
METHOXAMINE HYDROCHLORIDE structure
CAS No.
61-16-5
Chemical Name:
METHOXAMINE HYDROCHLORIDE
Synonyms
vasoxyl;Mexan;Vasylox;vasoxine;METHOXAMINE HCL;vasoxylhydrochloride;Naproxen Impurity 47;vasoxinehydrochloride;pressominhydrochloride;Methoxamine hydrochlorid
CBNumber:
CB1380846
Molecular Formula:
C11H18ClNO3
Molecular Weight:
247.72
MDL Number:
MFCD00058607
MOL File:
61-16-5.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:07
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METHOXAMINE HYDROCHLORIDE Properties

Melting point 215℃
refractive index 1.5204
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 9.2(at 25℃)
CAS DataBase Reference 61-16-5(CAS DataBase Reference)
FDA UNII 8MB4MJ9R7L

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  DN4025000

METHOXAMINE HYDROCHLORIDE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M6524 Methoxamine hydrochloride 61-16-5 500mg $187 2024-03-01 Buy
Sigma-Aldrich M6524 Methoxamine hydrochloride 61-16-5 1g $336 2024-03-01 Buy
TRC M260740 MethoxamineHydrochloride(MixtureofDiastereomers) 61-16-5 250mg $160 2021-12-16 Buy
American Custom Chemicals Corporation API0003335 METHOXAMINE HYDROCHLORIDE 95.00% 61-16-5 0.5G $538 2021-12-16 Buy
Medical Isotopes, Inc. 41303 MethoxamineHCl(MixtureofDiastereomers) 61-16-5 250mg $650 2021-12-16 Buy
Product number Packaging Price Buy
M6524 500mg $187 Buy
M6524 1g $336 Buy
M260740 250mg $160 Buy
API0003335 0.5G $538 Buy
41303 250mg $650 Buy

METHOXAMINE HYDROCHLORIDE Chemical Properties,Uses,Production

Originator

Vasoxyl ,Burroughs-Wellcome,US,1949

Uses

Methoxamine is an α1-adrenergic receptor agonist. It induces vasoconstriction of skin and splanchnic blood vessels, thereby increasing peripheral vascular resistance and raising mean arterial blood pressure.

Uses

Antihypotensive;Alpha adrenergic agonist

Uses

anti-fungal

Definition

ChEBI: Methoxamine hydrochloride is a dimethoxybenzene.

Manufacturing Process

2,5-Dimethoxypropiophenone is treated in absolute ether with methyl nitrite and hydrogen chloride. The hydrochloride of 2,5-dimethoxy-αisonitrosopropiophenone crystallizes out of the solution. It is removed, the base is liberated and crystallized from benzene-heptane forming yellow leaflets that melt at about 97° to 98°C. This isonitrosoketone is dissolved in absolute alcohol containing an excess of hydrogen chloride and is hydrogenated with palladized charcoal, yielding β-(2,5-dimethoxyphenyl)-βketoisopropylamine hydrochloride, a salt that melts at about 176°C with decomposition.
12.3 g (1/20 mol) of β-(2,5-dimethoxyphenyl)-β-ketoisopropylamine hydrochloride (MP 176°C) is dissolved in 50 cc of water and hydrogenated with platinum oxide platinum black in the customary Adams-Burgess Parr apparatus. About 1/20 mol of hydrogen is absorbed, after which the solution is filtered off from the catalyst, evaporated to dryness in vacuo and recrystallized from absolute alcohol, absolute ether being added to decrease solubility. The hydrochloride is thus obtained in substantially theoretical yield. It crystallizes in plates and melts at 215°C.

Therapeutic Function

Hypertensive

Biochem/physiol Actions

α1-adrenoceptor agonist.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. An FDA proprietary drug. When heated to decomposition it emits very toxic fumes of HCl and NOx.

METHOXAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Hydrogen Nitrous acid methyl ester

Preparation Products

METHOXAMINE HYDROCHLORIDE Suppliers

Global( 107)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Xiamen AmoyChem Co., Ltd 		+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569265 +86-18612256290 1056@dideu.com China 3581 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418671 sales@tnjchem.com China 34572 58
Unipharm pharmaceutical industry Co., Ltd 		536-8266195 +8613953676784 lee@unipharm-sd.com China 1206 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 9320 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Xiamen AmoyChem Co., Ltd 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Shaanxi Dideu Medichem Co. Ltd 		58
TargetMol Chemicals Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Unipharm pharmaceutical industry Co., Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58

View Lastest Price from METHOXAMINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHOXAMINE HYDROCHLORIDE USP/EP/BP pictures 2021-08-13 METHOXAMINE HYDROCHLORIDE USP/EP/BP
61-16-5
 US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
MethoxaMine Hydrochloride pictures 2021-07-20 MethoxaMine Hydrochloride
61-16-5
 US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
METHOXAMINE HYDROCHLORIDE pictures 2019-08-05 METHOXAMINE HYDROCHLORIDE
61-16-5
 US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co

61-16-5(METHOXAMINE HYDROCHLORIDE)Related Search:

2,5-Dimethoxyphenethylamine hydrochloride 2,5-DIMETHOXYBENZYL ALCOHOL 2-Methoxyphenethylamine Norfenefrine hydrochloride methoxamine
2-Amino-1-(2,5-dimethoxyphenyl)ethanol N-desmethylmethoxyphenamine Butoxamine hydrochloride METHOXAMINE HYDROCHLORIDE ISOPROPYLAMINE HYDROCHLORIDE
2-AMINO-1-(3-METHOXY-PHENYL)-ETHANOL HCL 2-(2-aminopropyl)phenol 2-amino-1-(3-methoxyphenyl)ethanol 2-AMINO-1-(2-METHOXY-PHENYL)-ETHANOL HCL 2-AMINO-1-(2-METHOXYPHENYL)ETHANOL
2-HYDROXY-5-METHOXYBENZYL ALCOHOL 1-(2,5-DIMETHOXYPHENYL)-2-AMINOPROPANEHYDROCHLORIDE 2-(2-aminoethyl)phenol

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vasoxylhydrochloride Methoxamine Hydrochloride (200 mg) 2-aMino-1-(2,5-diMethoxyphenyl)propan-1-ol hydrochloride MethoxaMine Hydrochloride (Mixture of DiastereoMers) BenzeneMethanol,a-(1-aMinoethyl)-2,5-diMethoxy-,hydrochloride (1:1) α-[1-Aminoethyl]-2,5-dimethoxybenzenemethanol hydrochloride α-(1-aminoethyl)-2,5-dimethoxybenzyl alcohol hydrochloride 2-Amino-1-hydroxy-1-(2,5-dimethoxyphenyl)propane hydrochloride a-(a-Aminoethyl)-2,5-dimethoxybenzyl alcohol hydrochloride Benzenemethanol, a-(1-aminoethyl)-2,5-dimethoxy-, hydrochloride (9CI) Benzyl alcohol, a-(1-aminoethyl)-2,5-dimethoxy-, hydrochloride (8CI) Beta-hydroxy-beta-(2,5-dimethoxyphenol)-isopropylamine hydrochloride b-Hydroxy-b-(2,5-dimethoxyphenyl)isopropylamine hydrochloride Vasylox Mexan ALPHA-[1-AMINOETHYL]-2,5-DIMETHOXYBENZYL ALCOHOL HYDROCHLORIDE 1-(2,5-dimethoxyphenyl)-2-aminopropanol 2-amino-1-(2,5-dimethoxyphenyl)-1-propanolhydrochloride alpha-(1-aminoethyl)-2,5-dimethoxy-benzenemethanohydrochloride alpha-(1-aminoethyl)-2,5-dimethoxybenzenemethanolhydrochloride alpha-(1-aminoethyl)-2,5-dimethoxy-benzylalcohohydrochloride Methoxamine hydrochlorid alpha-(alpha-aminoethyl)-2,5-dimethoxybenzylalcoholhydrochloride beta-(2,5-dimethoxyphenyl)-beta-hydroxyisopropylaminehydrochloride beta-hydroxy-beta-(2,5-dimethoxyphenyl)isopropylaminehydrochloride beta-hydroxy-beta-(2,5-dimethoxyphenyl)-isopropylaminehydrochloride pressominhydrochloride vasoxine vasoxinehydrochloride METHOXAMINE HCL METHOXAMINE HYDROCHLORIDE Benzenemethanol,α-(1-aminoethyl)-2,5-dimethoxy-,hydrochloride(1:1) METHOXAMINE HYDROCHLORIDE USP/EP/BP Methoxamine hydrochloride salt vasoxyl Naproxen Impurity 47 61-16-5 C11H19Cl2NO3 alpha1-adrenoceptor agonist. A type adrenergic receptor stimulants