5-Bromouridine
- CAS No.
- 957-75-5
- Chemical Name:
- 5-Bromouridine
- Synonyms
- 5-BrU;5-Br-rU;5-Br-Ur;5-Br-Uridine;5-bromo-uridin;5-BROMOURIDINE;5'-BROMOURIDINE;5-Bromo-D-uridine;Uridine, 5-bromo-;5-Bromouridine,98%
- CBNumber:
- CB1683763
- Molecular Formula:
- C9H11BrN2O6
- Molecular Weight:
- 323.1
- MDL Number:
- MFCD00006528
- MOL File:
- 957-75-5.mol
- MSDS File:
- SDS
Melting point | 180-182 °C (dec.) (lit.) |
---|---|
alpha | -11 º (c=2 in H2O) |
Density | 1.9322 (rough estimate) |
refractive index | 1.6520 (estimate) |
storage temp. | -20°C |
solubility | Water (Sonicated) |
form | Solid |
pka | 7.73±0.10(Predicted) |
color | Off-White |
optical activity | [α]22/D 11°, c = 2 in H2O |
Water Solubility | Insoluble in water. |
BRN | 33664 |
CAS DataBase Reference | 957-75-5(CAS DataBase Reference) |
FDA UNII | KEY8PG1BRC |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H225 | |||||||||
Precautionary statements | P210-P403+P235 | |||||||||
Safety Statements | 22-24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | YU7300000 | |||||||||
F | 10 | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
5-Bromouridine price More Price(38)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 850187 | 5-Bromouridine 98% | 957-75-5 | 250mg | $45.3 | 2024-03-01 | Buy |
Sigma-Aldrich | 850187 | 5-Bromouridine 98% | 957-75-5 | 1g | $112 | 2024-03-01 | Buy |
TCI Chemical | B0666 | 5-Bromouridine >99.0%(HPLC) | 957-75-5 | 1g | $89 | 2024-03-01 | Buy |
TCI Chemical | B0666 | 5-Bromouridine >99.0%(HPLC) | 957-75-5 | 100mg | $25 | 2024-03-01 | Buy |
Alfa Aesar | A18507 | 5-Bromouridine, 98% | 957-75-5 | 0.25g | $24.65 | 2024-03-01 | Buy |
5-Bromouridine Chemical Properties,Uses,Production
Description
5-Bromouridine is an energy-related metabolite that is a precursor of uridine. 5-Bromouridine binds to the nuclear DNA in cells, where it can act as a transcriptional regulator. 5-Bromouridine is used in the treatment of malignant brain tumors, where it can inhibit tumor growth by binding to the dna of cancer cells and preventing the synthesis of proteins required for cell division.
Chemical Properties
WHITE FINE POWDER
Uses
5-Bromouridine is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry. It possesses anti-viral activity and inhibits the activity of viruses such as human immunodeficiency virus.
Uses
5-Bromouridine is a uridine (U829910) derivative and is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry.
Definition
ChEBI: A uridine having a bromo substituent at the 5-position.
Purification Methods
Recrystallise it from 96% EtOH. UV max 279nm (log 3.95)in 2O pH 1.9. RF in n -BuOH/AcOH/H2O (4:4:1) is 0.49; in n-BuOH/EtOH/H2O (40:11:9) it is 0.46 and in isoPrOH/25%NH3/H2O (7:1:2) it is 0.53 using Whatman No 1 paper. [Pryst.s & Sorm Collect Czech Chem Commmun 29 2956 1964, Beilstein 31 H 24.]
5-Bromouridine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
View Lastest Price from 5-Bromouridine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-18 | 5-Bromouridine
957-75-5
|
US $0.00 / KG | 1KG | 99.0% | 500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-04-28 | 5-Bromouridine
957-75-5
|
US $50.00 / kg | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd | ||
2023-08-11 | 5-Bromouridine
957-75-5
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
- 5-Bromouridine
957-75-5
- US $0.00 / KG
- 99.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
- 5-Bromouridine
957-75-5
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
- 5-Bromouridine
957-75-5
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd