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ECHIMIDINE

CAS No.
520-68-3
Chemical Name:
ECHIMIDINE
Synonyms
C10299;ECHIMIDINE;(+)-ECHIMIDINE;7-Angelyl-9-echimidinylretronecine;(7aR)-7-[(Ξ)-2,3-dihydroxy-2-((Ξ)-1-hydroxy-ethyl)-3-methyl-butyryloximethyl]-1c-(2-methyl-cis-crotonoyloxy)-(7ar)-2,3,5,7a-tetrahydro-1H-pyrrolizin;L-threo-Pentitol, 1,5-dideoxy-2-C-methyl-3-C-[[[(1R,7aR)-2,3,5,7a-tetrahydro-1-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-1H-pyrrolizin-7-yl]methoxy]carbonyl]-
CBNumber:
CB21444797
Molecular Formula:
C20H31NO7
Molecular Weight:
397.46
MDL Number:
MFCD02656389
MOL File:
520-68-3.mol
Last updated:2023-05-04 17:34:39

ECHIMIDINE Properties

Melting point >133°C (dec.)
Boiling point 520.9°C (rough estimate)
Density 1.26±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 1.5614 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 12.45±0.29(Predicted)
form Solid
color Light Beige
FDA UNII 31NEL09379

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H310
Precautionary statements  P262-P280-P301+P330+P331+P310-P302+P352+P310-P361+P364
RIDADR  1544
HazardClass  6.1(b)
PackingGroup  III

ECHIMIDINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89553 Echimidine phyproof? Reference Substance 520-68-3 10MG $636 2022-05-15 Buy
TRC E325580 (+)-Echimidine 520-68-3 0.25mg $360 2021-12-16 Buy
American Custom Chemicals Corporation PXT0001740 ECHIMIDINE 95.00% 520-68-3 5MG $499.09 2021-12-16 Buy
Arctom CFN00254 Echimidine 520-68-3 5mg $498 2021-12-16 Buy
Product number Packaging Price Buy
PHL89553 10MG $636 Buy
E325580 0.25mg $360 Buy
PXT0001740 5MG $499.09 Buy
CFN00254 5mg $498 Buy

ECHIMIDINE Chemical Properties,Uses,Production

Uses

(+)-Echimidine, is a a hepatotoxic pyrrolizidine alkaloid. It is found to be present in comfrey, inducing genotoxicity and carcinogenicity.

Definition

ChEBI: Echimidine is a member of pyrrolizines.

ECHIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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ECHIMIDINE 7-Angelyl-9-echimidinylretronecine C10299 (+)-ECHIMIDINE L-threo-Pentitol, 1,5-dideoxy-2-C-methyl-3-C-[[[(1R,7aR)-2,3,5,7a-tetrahydro-1-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-1H-pyrrolizin-7-yl]methoxy]carbonyl]- (7aR)-7-[(Ξ)-2,3-dihydroxy-2-((Ξ)-1-hydroxy-ethyl)-3-methyl-butyryloximethyl]-1c-(2-methyl-cis-crotonoyloxy)-(7ar)-2,3,5,7a-tetrahydro-1H-pyrrolizin 520-68-3 C20H31NO7