Dimethyl fluoromalonate
- CAS No.
- 344-14-9
- Chemical Name:
- Dimethyl fluoromalonate
- Synonyms
- METHYL 2-FL;DIMETHYL FLUOROMALONATE;Dimethyl 2-fluoromalonate;Dimethylfluoromalonate97%;Dimethyl fluoromalonate 97%;fluoro-malonicaciddimethyles;imethyl2-fluoropropanedioate;Dimethyl 2-fluoromalonate 97%;Dimethyl 2-fluoropropanedioate;fluoro-malonicaciddimethylester
- CBNumber:
- CB2216739
- Molecular Formula:
- C5H7FO4
- Molecular Weight:
- 150.11
- MDL Number:
- MFCD00054680
- MOL File:
- 344-14-9.mol
| Boiling point | 76 °C |
|---|---|
| Density | 1.4g/ml |
| refractive index | 1.4032 |
| Flash point | 111-112°C/45mm |
| pka | 10.35±0.46(Predicted) |
| form | solid |
| color | Colourless to off-white / liquid |
| BRN | 1768414 |
| CAS DataBase Reference | 344-14-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H318 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | T,C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45-23 2636/37/3945-20 | |||||||||
| RIDADR | 3265 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29171900 | |||||||||
| NFPA 704 |
|
Dimethyl fluoromalonate price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | L16751 | Dimethyl fluoromalonate, 97% | 344-14-9 | 1g | $67.65 | 2024-03-01 | Buy |
| Alfa Aesar | L16751 | Dimethyl fluoromalonate, 97% | 344-14-9 | 5g | $232.65 | 2024-03-01 | Buy |
| TRC | D465743 | Dimethylfluoromalonate | 344-14-9 | 500mg | $65 | 2021-12-16 | Buy |
| TRC | D465743 | Dimethylfluoromalonate | 344-14-9 | 100mg | $45 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK250144 | Dimethylfluoromalonate 98% | 344-14-9 | 1g | $58 | 2021-12-16 | Buy |
Dimethyl fluoromalonate Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
Dimethyl 2-fluoromalonate is used as an intermediate in organic synthesis.
Preparation
synthesis of dimethyl 2-fluoromalonate: Dimethyl malonate (19.8 g, 0.15 mol) and Cu(NO3)2·2.5H2O (3.50 g, 15 mmol) were dissolved in acetonitrile (85 mL), the mixture was cooled to 0–5 °C and stirred at 650 rpm using an overhead stirrer. After purging the system with N2 for 5 minutes, fluorine gas (20% v/v in N2, 50 mL min-1 , 170 mmol) was introduced into the reaction mixture for 7 h. After purging with nitrogen for 20 minutes, the solvent was removed in vacuo and the residue was partitioned between water (30 mL) and ethyl acetate (20 mL). The aqueous phase was extracted with ethyl acetate (2 × 20 mL) and the combined organic layer was washed with saturated brine (20 mL). After drying over sodium sulphate, the solvent was evaporated under reduced pressure to give dimethyl 2-fluoromalonate (21.8 g, 97% yield, 95% purity) as a colourless oil;
IR (neat, cm-1 ) 2962, 1748, 1438, 1250, 1206, 1112, 1016; δH (CDCl3, 400 MHz) 3.85 (6H, s, CH3), 5.31 (1H, d, 2 JHF 48.0, CHF); δF (CDCl3, 376 MHz): -195.73 (d, 2 JHF 48.0, CH–F); δC (CDCl3, 100 MHz) 53.48 (CH3), 85.19 (d, 1 JCF 197.2, C–F), 164.39 (d, 2 JCF 24.0, CvO); m/z (EI+ ) 150 (3%, [M]+ ), 119 (42%, [M-OMe]+ ), 91 (73%, [M-COOMe]+ ), 59 (100%, [COOMe]+ ).
Dimethyl fluoromalonate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 | sales@allfluoro.com | China | 5791 | 58 |
View Lastest Price from Dimethyl fluoromalonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-10-10 | Dimethyl fluoromalonate
344-14-9
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-07-13 | Dimethyl fluoromalonate
344-14-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-09-05 | Dimethyl fluoromalonate
344-14-9
|
US $1.80-3.60 / KG | 1KG | 99% | 88KG | Career Henan Chemical Co |
-
- Dimethyl fluoromalonate
344-14-9
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Dimethyl fluoromalonate
344-14-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Dimethyl fluoromalonate
344-14-9
- US $1.80-3.60 / KG
- 99%
- Career Henan Chemical Co