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RAF mutant-IN-1

CAS No.
2340020-82-6
Chemical Name:
RAF mutant-IN-1
Synonyms
RAF MUTANT-IN-1;RAF mutant IN 1,RAF mutantIN1
CBNumber:
CB25540349
Molecular Formula:
C23H17Cl2FN6O2S
Molecular Weight:
531.39
MDL Number:
MFCD32201092
MOL File:
2340020-82-6.mol
Last updated:2023-05-21 10:59:17

RAF mutant-IN-1 Properties

storage temp. Store at -20°C
solubility Soluble in DMSO

RAF mutant-IN-1 Chemical Properties,Uses,Production

Description

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1]. C-RAF 340D/Y341D|21 nM (IC50)|B-RafV600E|30 nM (IC50)|BRAFWT|392 nM (IC50)

References

[1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1.

RAF mutant-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

RAF mutant-IN-1 Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24023 58
RAF MUTANT-IN-1 RAF mutant IN 1,RAF mutantIN1 2340020-82-6