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S-NITROSOGLUTATHIONE

CAS No.
57564-91-7
Chemical Name:
S-NITROSOGLUTATHIONE
Synonyms
SNOG;GSNO;GNSO;RVC 588;GSNO, SNOG;RVC 588 (peptide);nitrosoglutathione;S-NITROSOGLUTATHIONE;S-Nitrosylglutathione;Talabostat Impurity 27
CBNumber:
CB2664125
Molecular Formula:
C10H16N4O7S
Molecular Weight:
336.32
MDL Number:
MFCD00214341
MOL File:
57564-91-7.mol
MSDS File:
SDS
Last updated:2023-09-04 15:51:00

S-NITROSOGLUTATHIONE Properties

Melting point >170°C (dec.)
Density 1.68
refractive index 1.6000 (estimate)
storage temp. -20°C
solubility DMSO (Slightly), Water (Slightly)
form Pink solid
pka 2.21±0.10(Predicted)
color Off-White to Pink
Water Solubility Soluble to 100 mM in water
Stability Hygroscopic
CAS DataBase Reference 57564-91-7(CAS DataBase Reference)
FDA UNII 78RRI89ZTO

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H311-H331
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  MC0558000
NFPA 704
0
2 0

S-NITROSOGLUTATHIONE price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 487920 S-Nitrosoglutathione A utility carrier of nitric oxide. 57564-91-7 10mg $96.7 2024-03-01 Buy
Sigma-Aldrich 487920 S-Nitrosoglutathione A utility carrier of nitric oxide. 57564-91-7 1set $280 2024-03-01 Buy
Cayman Chemical 82240 S-Nitroso-L-glutathione ≥98% 57564-91-7 5mg $26 2024-03-01 Buy
Cayman Chemical 82240 S-Nitroso-L-glutathione ≥98% 57564-91-7 10mg $49 2024-03-01 Buy
Sigma-Aldrich N4148 S-Nitrosoglutathione ≥97% 57564-91-7 25mg $367 2024-03-01 Buy
Product number Packaging Price Buy
487920 10mg $96.7 Buy
487920 1set $280 Buy
82240 5mg $26 Buy
82240 10mg $49 Buy
N4148 25mg $367 Buy

S-NITROSOGLUTATHIONE Chemical Properties,Uses,Production

Description

S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.

Chemical Properties

Pink Powder

Uses

A carrier of nitric oxide, relaxing smooth muscle and inhibiting platelet activation

Uses

S-Nitrosoglutathione (GSNO) has been used:

  • as a standard in reversed phase chromatography coupled to chemical vapour generation and atomic fluorescence detector (RPC-CVGAFS) and reversed phase chromatography fluorimetric (RPC-FD).
  • as a standard in spectrophotometric and high-performance liquid chromatography (HPLC) assay.

Definition

ChEBI: S-nitrosoglutathione is a glutathione derivative that is glutathione in which the hydrogen attached to the sulfur has been replaced by a nitroso group. It has a role as a platelet aggregation inhibitor, a bronchodilator agent, a nitric oxide donor and a signalling molecule. It is a glutathione derivative and a nitrosothio compound. It is a conjugate acid of a S-nitrosoglutathione(2-).

General Description

A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

Biological Activity

A carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation.

Biochem/physiol Actions

Product does not compete with ATP.

storage

Desiccate at -20°C

70-18-8
57564-91-7
Synthesis of S-NITROSOGLUTATHIONE from Glutathione

S-NITROSOGLUTATHIONE Suppliers

Global( 165)Suppliers
Supplier Tel Email Country ProdList Advantage
Chongqing Chemdad Co., Ltd
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career henan chemical co
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TargetMol Chemicals Inc.
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Hubei Ipure Biology Co., Ltd
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Hefei TNJ Chemical Industry Co.,Ltd.
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HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514 ada@ipurechemical.com CHINA 3465 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
CD Chemical Group Limited
+8615986615575 info@codchem.com China 20356 58
Labnetwork lnc.
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View Lastest Price from S-NITROSOGLUTATHIONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
S-NITROSOGLUTATHIONE pictures 2020-01-13 S-NITROSOGLUTATHIONE
57564-91-7
US $1.00 / KG 1KG 98%-99.9% 100kg Career Henan Chemical Co
L-γ-GlutaMyl-S-nitroso-L-cysteinyl-glycine RVC 588 N-(N-L-gama-glutamyl-S-nitroso-L-cysteinyl)glycine RVC 588 (peptide) S-Nitrosylglutathione (S)-2-aMino-5-(((R)-1-((carboxyMethyl)aMino)-3-(nitrosothio)-1-oxopropan-2-yl)aMino)-5-oxopentanoic acid nitrosoglutathione(GSNO) L-γGlu-S-Nitroso-L-Cys-Gly-OH γGlu-S-Nitroso-Cys-Gly-OH S-Nitroso-L-glutathioneGSNO N-(N-L-γ- Glutamyl-S-nitroso -L-cysteinyl)glycine Glycine, L-g-glutamyl-S-nitroso-L-cysteinyl- S-Nitrosoglutathione (GSNO) N-(N-L-GAMMA-GLUTAMYL-S-NITROSO-L-CYSTEINYL)-GLYCINE S-NITROSOGLUTATHIONE S-NITROSO-L-GLUTATHIONE SNOG n-(n-l-gamma-glutamyl-2-nitroso-l-cysteinyl)-glycin nitrosoglutathione N-(N-L-g-Glutamyl-S-nitroso-L-cysteinyl)glycine (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-nitrososulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid N-(N-L-GAMMA-GLUTAMYL-S-NITROSO-L-CYSTEINYL)GLYCINE (S-NITROSOGLUTATHIONE) GSNO GNSO GSNO, SNOG S-NITROSO-L-GLUTATHIONE, 97+% S-Nitrosoglutathione - CAS 57564-91-7 - Calbiochem Glycine, L-γ-glutamyl-S-nitroso-L-cysteinyl- S-Nitrosoglutathione, ≥97% (2S)-2-amino-5-[[(1R)-2-(carboxymethylamino)-1-(nitrososulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid Talabostat Impurity 27 57564-91-7 C10H16N4O7S C10H15N4O7S Application Index Biochemicals and Reagents BioChemical Cell Signaling Enzymes Enzymes, Inhibitors, and Substrates NO Donors Nitric Oxide Metabolism Peptides Sulfur & Selenium Compounds Signalling Nitric Oxide Reagents Nitric Oxide