ChemicalBook >> CAS DataBase List >>D-Proline
D-Proline
- CAS No.
- 344-25-2
- Chemical Name:
- D-Proline
- Synonyms
- Proline;H-D-PRO-OH;D-PRO;D-Pro-OH;(R)-PYRROLIDINE-2-CARBOXYLIC ACID;(2R)-Pyrrolidine-2-carboxylic acid;D-PYRROLIDINE-2-CARBOXYLIC ACID;D-PyrroL;D-PROLINE;D(+)-PROLINE
- CBNumber:
- CB2754303
- Molecular Formula:
- C5H9NO2
- Molecular Weight:
- 115.13
- MDL Number:
- MFCD00064317
- MOL File:
- 344-25-2.mol
- MSDS File:
- SDS
Last updated:2024-04-22 15:59:48
| Melting point | 223 °C (dec.) (lit.) |
|---|---|
| Boiling point | 215.41°C (rough estimate) |
| alpha | 84.75 º (c=4, H2O) |
| Density | 1.36 |
| refractive index | 85 ° (C=4, H2O) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Methanol (Slightly), Water (Sparingly) |
| pka | 1.952(at 25℃) |
| form | Powder |
| color | White to yellow to pale brown |
| optical activity | [α]22/D +85.0°, c = 4 in H2O |
| Water Solubility | soluble >1000 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| BRN | 80811 |
| InChIKey | ONIBWKKTOPOVIA-SCSAIBSYSA-N |
| LogP | -0.060 (est) |
| CAS DataBase Reference | 344-25-2(CAS DataBase Reference) |
| FDA 21 CFR | 582.5650 |
| EWG's Food Scores | 1 |
| FDA UNII | L01Q4LGZ5L |
| EPA Substance Registry System | D-Proline (344-25-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36/37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
D-Proline price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 858919 | D-Proline ReagentPlus , ≥99% | 344-25-2 | 500mg | $46.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 858919 | D-Proline ReagentPlus , ≥99% | 344-25-2 | 5g | $114 | 2024-03-01 | Buy |
| TCI Chemical | P0994 | D-Proline >98.0%(T) | 344-25-2 | 5g | $76 | 2024-03-01 | Buy |
| TCI Chemical | P0994 | D-Proline >98.0%(T) | 344-25-2 | 25g | $242 | 2024-03-01 | Buy |
| Alfa Aesar | A10682 | D-Proline, 99% | 344-25-2 | 1g | $42.65 | 2024-03-01 | Buy |
D-Proline Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Occurrence
D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity.
Uses
proline is a skin-conditioning agent. An amino acid found in the collagen molecule.
Uses
Used in the synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(-)-Coniine, (S)-(+)-Pelletierine, (+)-.beta.-Conhydrine, and (S)-(-)-Ropivacaine and formal synthesis of (-)-Lasubine II and (+)-Cermizine C.
Uses
Labelled D-Proline Lasubine II and (+)-Cermizine C.
Definition
ChEBI: D-proline is the D-enantiomer of proline. It has a role as a mouse metabolite. It is a D-alpha-amino acid and a proline. It is a conjugate base of a D-prolinium. It is a conjugate acid of a D-prolinate. It is an enantiomer of a L-proline. It is a tautomer of a D-proline zwitterion.
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065
Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4
D-Proline Preparation Products And Raw materials
Raw materials
Preparation Products
N-Boc-D-proline
(1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID
Fmoc-Pro-OH
(S)-3-Amino-1-N-Boc-piperidine
2-Pyrrolidinecarbonitrile,(2R)-
1of3
Global( 700)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Maanshan Tiantai Biotechnology Co., Ltd. | +86-0555-8889890 +86-17356584060 | GM@tiantaibio-tech.com | China | 72 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5994 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 | sales@zhswyy.com | China | 278 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 16801 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
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- Dec 21，2023
- D-proline：A member of the D-amino acid family
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View Lastest Price from D-Proline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-26 | D-Proline
344-25-2
|
US $0.00-0.00 / kg | 0.10000000149011612kg | 99 | 20tons | Chongqing Zhihe Biopharmaceutical Co., Ltd. | |
 |
2024-04-22 | D-Proline
344-25-2
|
US $32.00-1.10 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-11-15 | D-Proline
344-25-2
|
US $0.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
D-Proline≥ 99% (Assay)
D-Proline,99%e.e.
(R)-(+)-PROLINE
D-2-PYRROLIDINECARBOXYLIC ACID
D(+)-PROLINE
D-PROLINE
H-D-PYRD(2)-OH
D-Proline,99%
H-D-PRO-OH UPS24 (IN BULK QUANTITY)
D-(+)-Prolin
Glycinate Fumasuan Salt
D-PROLINE, 99+% (98% EE/GLC)
D-(+)-PROLINE ((R)-(+)-PROLINE)
D-PROLINE extrapure
D-Proline-d3
D-Proline, (2R)-2-Carboxypyrrolidine
D-Proline ReagentPlus(R), >=99%
D-Proline Vetec(TM) reagent grade, 98%
D-PyrroL
idine-2-carboxyL
Captopril Impurity 32
D-Proline>
D-Proline，98%
D-Proline USP/EP/BP
dextro-(+)-proline
D-Proline CAS No. 344-25-2
D-Proline extrapure CHR, 99%
D-Pro-OH
(R)-PYRROLIDINE-2-CARBOXYLIC ACID
D-PYRROLIDINE-2-CARBOXYLIC ACID
D-PRO
H-D-PRO-OH
Proline
(2R)-Pyrrolidine-2-carboxylic acid
D-Proline (9CI, ACI)
Captopril Impurity 38
344-25-2
24344-25-2
145-85-3
344-25-5
C5H9NO2
CARBOXYLIC ACID
Amino Acid Derivatives
Proline
Peptide Synthesis
Specialty Synthesis
Amino Acids and Derivatives
Proline [Pro, P]
Amino Acids and Derivatives
alpha-Amino Acids
Amino Acids
Biochemistry
Amino Acids & Derivatives
Heterocycles
Isotope Labelled Compounds
Amino ACIDS SERIES
Miscellaneous Biochemicals
206-452-7