(R)-2-(2-Chlorophenyl)pyrrolidine
- CAS No.
- 823188-58-5
- Chemical Name:
- (R)-2-(2-Chlorophenyl)pyrrolidine
- Synonyms
- (R)-2-(2-Chlorophenyl)pyrrolidine;(2R)-2-(2-chlorophenyl)pyrrolidine;Pyrrolidine,2-(2-chlorophenyl)-, (2R)-
- CBNumber:
- CB2875729
- Molecular Formula:
- C10H12ClN
- Molecular Weight:
- 181.66
- MDL Number:
- MFCD06762524
- MOL File:
- 823188-58-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
(R)-2-(2-Chlorophenyl)pyrrolidine price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FC151298 | (R)-2-(2-Chlorophenyl)pyrrolidine | 823188-58-5 | 250mg | $267.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC151298 | (R)-2-(2-Chlorophenyl)pyrrolidine | 823188-58-5 | 500mg | $465 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0038887 | (R)-2-(2-CHLOROPHENYL)PYRROLIDINE 95.00% | 823188-58-5 | 5MG | $505.21 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC151298 | (R)-2-(2-Chlorophenyl)pyrrolidine | 823188-58-5 | 50mg | $77 | 2021-12-16 | Buy |
| Activate Scientific | AS8672 | (R)-2-(2-Chlorophenyl)pyrrolidine 95+% ee | 823188-58-5 | 1g | $729 | 2021-12-16 | Buy |
(R)-2-(2-Chlorophenyl)pyrrolidine Chemical Properties,Uses,Production
Chemical Properties
Flashing point: 107.5 °C . Vapour pressure: 0.0176mmHg at 25°C. (R)-2-(2-Chlorophenyl)pyrrolidine is a chiral molecule whose optical isomer is (S)-2-(2-Chlorophenyl)pyrrolidine.
Physical properties
A colorless crystal
Uses
(R)-2-(2-Chlorophenyl)pyrrolidine can be used as an intermediate for organic synthesis.
Synthesis
To a dry Schlenk flask under nitrogen is added 0.540 g of (R, R)- (+)-ETHYLENE-1, 2- bis (N5-4, 5,6, 7-TETRAHYDRO-L-INDENYL) titanium difluoride and 120 mL of dry THF. To this solution are added under nitrogen in the following order: 2- (2-chlorophenyl)-pyrroline (15 g), phenylsilane (15 g), pyrrolidine (0.48 mL), and MeOH (0.24 mL). The solution is stirred at RT for 48 h, then the mixture is diluted with 350 mL of diethylether and carefully added with vigorous stirring to 1200 mL of 1 M HCI. The aqueous layer is separated and extracted with three portions of diethyl ether (300 mL each). The aqueous layer is made basic with 3M NAOH and extracted with 5 portions of diethyl ether (200 mL each). The combined ether layers are dried over magnesium sulfate and concentrated in vacuo. The residue is purified by vacuum transfer to give (R)-2-(2-Chlorophenyl)pyrrolidine (15 g, 93%) as a colorless oil.
(R)-2-(2-Chlorophenyl)pyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-2-(2-Chlorophenyl)pyrrolidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Xinghan Biotechnology Co., Ltd | +8618698089028 | 1725517238@qq.com | China | 2479 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5905 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Tianjin Xinghan Biotechnology Co., Ltd | 13230698506 18698089028 | 1725517238@qq.com | China | 5009 | 58 |
| LABTER PHARMATECH(BEIJING) CO.,LTD | 010-56330744 18310155299 | sales@labter.com.cn | China | 23339 | 55 |
| Chongqing Acemol Technology Co.,Ltd | 023-86822659 18611316925 | sales@acemol.com | China | 957 | 55 |
| Shanghai CR Corporation Limited | 4006653949 | fred.wen@crcorporation.cn | China | 10108 | 58 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22346 | 58 |
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