methyl orsellinate
- CAS No.
- 3187-58-4
- Chemical Name:
- methyl orsellinate
- Synonyms
- Methyl;METHYL ORSELLINATE;Methyl o-orsellinate;Orsellinic acid methyl;o-Orsellinic acid methyl;6-Methyl-β-resorcylicacidmethyl;6-Methyl-β-resorcylic acid methyl;BENZOIC ACID,2,4-DIHYDROXY-6-METHYL-, METHYL ESTER
- CBNumber:
- CB31484897
- Molecular Formula:
- C9H10O4
- Molecular Weight:
- 182.17
- MDL Number:
- MFCD00184668
- MOL File:
- 3187-58-4.mol
| Melting point | 141-142℃ |
|---|---|
| Boiling point | 339℃ |
| Density | 1.296 |
| Flash point | 138℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.27±0.23(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3 |
| InChIKey | NCCWCZLEACWJIN-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=C(C)C=C(O)C=C1O |
| LogP | 2.380 (est) |
| EPA Substance Registry System | Benzoic acid, 2,4-dihydroxy-6-methyl-, methyl ester (3187-58-4) |
methyl orsellinate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M302230 | Methyl2,4-Dihydroxy-6-methylbenzoate | 3187-58-4 | 50mg | $70 | 2021-12-16 | Buy |
| TRC | M302230 | Methyl2,4-Dihydroxy-6-methylbenzoate | 3187-58-4 | 500mg | $205 | 2021-12-16 | Buy |
| TRC | M302230 | Methyl2,4-Dihydroxy-6-methylbenzoate | 3187-58-4 | 2.5g | $870 | 2021-12-16 | Buy |
| Matrix Scientific | 149616 | Methyl 2,4-dihydroxy-6-methylbenzoate 95% | 3187-58-4 | 5g | $1292 | 2021-12-16 | Buy |
| AK Scientific | W1988 | Methylorsellinate | 3187-58-4 | 5g | $1794 | 2021-12-16 | Buy |
methyl orsellinate Chemical Properties,Uses,Production
Uses
Methyl 2,4-Dihydroxy-6-methylbenzoate (methyl orsellinate) is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.
Definition
ChEBI: Orsellinic acid methyl ester is a hydroxybenzoic acid. It has a role as a metabolite.
Biochem/physiol Actions
Methyl orsellinate, an antifungal compound, is produced during submerged culture from Sparassis crispa. Methyl orsellinate have appeared to have higher antifungal activity than sparassol. Methyl orsellinate is a phytotoxic compound; it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. It could inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM; the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity; methyl orsellinate may treat the type 2 diabetes and obesity.
methyl orsellinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3000 | 58 |
| Xiamen Work-For-World Medicine Co.,Ltd. | +undefined15921822462 | keqingyong@wfwmed.com | China | 203 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| PNP Biotech Co. Ltd | +8618516098983 | sales@pnpbiotech.com | China | 1001 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
View Lastest Price from methyl orsellinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-28 | Methyl 2,4-dihydroxy-6-methylbenzoate
3187-58-4
|
US $0.00 / kg | 25kg | 98% | Inquiry | PNP Biotech Co. Ltd | |
 |
2024-03-27 | Methyl orsellinate
3187-58-4
|
US $1.00-1.00 / kg | 1kg | 99%HPLC | kg | Xiamen Work-For-World Medicine Co.,Ltd. | |
 |
2023-10-26 | METHYL ORSELLINATE
3187-58-4
|
US $0.00 / KG | 0.1KG | 98% | 1000KGS | Zhengzhou Anbu Chem Co.,Ltd |
-
- Methyl 2,4-dihydroxy-6-methylbenzoate
3187-58-4
- US $0.00 / kg
- 98%
- PNP Biotech Co. Ltd
-
- Methyl orsellinate
3187-58-4
- US $1.00-1.00 / kg
- 99%HPLC
- Xiamen Work-For-World Medicine Co.,Ltd.
-
- METHYL ORSELLINATE
3187-58-4
- US $0.00 / KG
- 98%
- Zhengzhou Anbu Chem Co.,Ltd