ChemicalBook >> CAS DataBase List >>GSK2110183

GSK2110183

GSK2110183 structure

CAS No.: 1047634-63-8

Chemical Name:: GSK2110183

Synonyms: CS-1729;GSK2110183;Afuresertib-F free base;Afuresertib (GSK2110183);GSK2110183;GSK 2110183;GSK-2110183;N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide;N-((S)-1-Amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide;(S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide;N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide;2-Thiophenecarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-

CBNumber:: CB32715633

Molecular Formula:: C18H16Cl2F2N4OS

Molecular Weight:: 445.31

MDL Number:

MOL File:: 1047634-63-8.mol

Last updated:2023-07-14 17:34:38

Request For Quotation

GSK2110183 Properties

Boiling point	539.7±50.0 °C(Predicted)
Density	1.54±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	12.92±0.46(Predicted)

GSK2110183 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	FG103755	GSK 2110183	1047634-63-8	10mg	$175	2021-12-16	Buy
AK Scientific	7590DN	N-[(2S)-1-Amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide	1047634-63-8	10mg	$286	2021-12-16	Buy
Biosynth Carbosynth	FG103755	GSK 2110183	1047634-63-8	50mg	$612.5	2021-12-16	Buy
Crysdot	CD31004719	GSK2110183 98+%	1047634-63-8	50mg	$1042	2021-12-16	Buy
Chemenu	CM188229	(S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide 98%	1047634-63-8	100mg	$1374	2021-12-16	Buy

Product number	Packaging	Price	Buy
FG103755	10mg	$175	Buy
7590DN	10mg	$286	Buy
FG103755	50mg	$612.5	Buy
CD31004719	50mg	$1042	Buy
CM188229	100mg	$1374	Buy

GSK2110183 Chemical Properties,Uses,Production

Description

Afuresertib-F is an analogue of Afuresertib with one more flurorine-atom compared to its parent drug Afuresertib. Afuresertib-F is an ATK inhibitor. Afuresertib, also known as GSK-2110183 or GSK-2110183C, is an cancer drug candidate under clinical trial.

Uses

An ATK inhibitorAfuresertib-F is used in methods of treating myeloproliferative neoplasms using a combination of a MDM2 inhibitor and a therapeutic agent.

GSK2110183 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK2110183 Suppliers

Global( 34)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Amadis Chemical Company Limited	58
Shanghai Boyle Chemical Co., Ltd.	55
MedChemexpress LLC	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56

1047634-63-8(GSK2110183)Related Search:

N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide GSK-2126458 ABT 702 Dihydrochloride Danirixin daprodustat,GSK1278863

GSK1940029 GSK 189254A gsk2200150a 4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%

1of2

N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide GSK2110183 Afuresertib (GSK2110183) CS-1729 N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide GSK2110183;GSK 2110183;GSK-2110183 2-Thiophenecarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)- Afuresertib-F free base (S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide N-((S)-1-Amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide 1047634-63-8 C18H16Cl2F2N4OS